REAL OPTION MODELS FOR SIMULATING DIGESTER SYSTEM ADOPTION ON LIVESTOCK FARMS IN EMILIA-ROMAGNA

Innovation and new technology adoption represent two central elements for the enterprise and industry development process in agriculture. The objective of this paper is to develop a farmhousehold model able to simulate the impacts of uncertainty in SFP, the selling price of energy and agricultural product prices parameters on the adoption of methane digester for biogas production. The model implemented is based on a real option approach that includes investment irreversibility and stochasticity in relevant parameters. The results show the relevance of uncertainty in determining the timing of adoption and emphasise the importance of predictability as a major component of policy design

EM Training of Hidden Markov Models for Shape Recognition Using Cyclic Strings

Shape descriptions and the corresponding matching techniques must be robust to noise and invariant to transformations for their use in recognition tasks. Most transformations are relatively easy to handle when contours are represented by strings. However, starting point invariance is difficult to achieve. One interesting possibility is the use of cyclic strings, which are strings with no starting and final points. Here we present the use of Hidden Markov Models for modelling cyclic strings and their training using Expectation Maximization. Experimental results show that our proposal outperforms other methods in the literature

A Framework for Recommending Multimedia Cultural Visiting Paths

In this work, we present a general framework for Cultural Heritage applications able to uniformly manage heterogeneous multimedia data coming from several web repositories and to provide context- Aware recommendation services in order to generate dynamic multimedia visiting paths useful for the users during the exploration of different kinds of cultural sites. A specific application of our system within the cultural heritage domain is proposed together with some experimental results

FAVOR (FAst Variability Optical Registration) -- A Two-telescope Complex for Detection and Investigation of Short Optical Transients

An astronomical complex intended to detect optical transients (OTs) in a wide field and follow them up with high time resolution investigation is described.Comment: 4 pages, 3 figures. To be published in "Il Nuovo Cimento", Proceedings of the 4th Rome Workshop on Gamma-Ray Bursts in the Afterglow Era, eds. L. Piro, L. Amati, S. Covino, B. Gendr

Management of patients with atrial fibrillation: different therapeutic options and role of electrophysiology-guided approaches.

At present the approach to atrial fibrillation treatment is based on the electrophysiological patterns of atrial fibrillation (on the basis of multiple intra-atrial recordings or sophisticated new mapping techniques) only in a restricted minority of patients, those who are candidate to ablation of the substrate and/or of the triggers. Atrial fibrillation has a broad spectrum of clinical presentations and a heterogeneous electrophysiological pattern. The treatment of this arrhythmia, both with drugs and non pharmacological treatments, has been based, classically, on empirical basis and on a clinically-guided staged-approach. The limitations of pharmacological treatment led in recent years to the development of a wide spectrum of non pharmacological treatments. This implies a change in the approach to atrial fibrillation and the need to identify potentially ideal candidates to complex and expensive treatments. In this view it is currently under investigation the possibility to identify potential responders to a definitive treatment or a combination of treatments (both pharmacological and non-pharmacological) on the basis of the electrophysiological pattern

From the dual function lead AP2238 to AP2469, a multi-target-directed ligand for the treatment of Alzheimer\u2019s disease

The development of drugs with different pharmacological properties appears to be an innovative therapeutic approach for Alzheimer\u2019s disease. In this article, we describe a simple structural modification of AP2238, a first dual function lead, in particular the introduction of the catechol moiety performed in order to search for multi-target ligands. The new compound AP2469 retains antiacetylcholinesterase (AChE) and beta-site amyloid precursor protein cleaving enzyme (BACE)1 activities compared to the reference, and is also able to inhibit Ab42 self aggregation, Ab42 oligomer-binding to cell membrane and subsequently reactive oxygen species formation in both neuronal and microglial cells. The ability of AP2469 to interfere with Ab42 oligomer-binding to neuron and microglial cell membrane gives this molecule both neuroprotective and antiinflammatory properties. These findings, together with its strong chain-breaking antioxidant performance, make AP2469 a potential drug able to modify the course of the diseas

Study of the cyclotron feature in MXB 0656-072

We have monitored a type II outburst of the Be/X-ray binary MXB 0656−072 in a series of pointed RXTE observations during October through December 2003. The source spectrum shows a cyclotron resonance scattering feature at 32.8 +0.5 −0.4 keV, corresponding to a magnetic field strength of 3.67 +0.06 −0.04 × 10 12 G and is stable through the outburst and over the pulsar spin phase. The pulsar, with an average pulse period of 160.4 ± 0.4s,shows a spin-up of 0.45 s over the duration of the outburst. From optical data, the source distance is estimated to be 3.9 ± 0.1 kpc and this is used to estimate the X-ray luminosity and a theoretical prediction of the pulsar spin-up during the outburst