1,150 research outputs found

    Review of the twelfth West Coast retrovirus meeting

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    Every year the Cancer Research Institute from University of California at Irvine organizes the West Coast Retrovirus Meeting where participants have a chance to discuss the latest progress in understanding the pathology of retroviruses. The 12(th )meeting was held at the Hyatt Regency Suites in Palm Springs, California from October 6(th )to October 9(th )2005, with the major focus on human immunodeficiency virus (HIV) pathogenesis. Philippe Gallay from The Scripps Research Institute and Thomas J. Hope from Northwestern University organized the meeting, which covered all the steps involved in the lifecycle of retroviruses with an emphasis on virus:host interactions. The trend in research appeared to be on the restriction of viral infection, both by the endogenous, cellular restriction factors, as well as by the potential antimicrobial compounds of known or unknown mechanisms. Additionally, new stories on the inevitable feedback from the host immune system were presented as well. HIV still represents a challenge that an army of motivated people has been working on for over 20 years. And yet, the field has not reached the plateau in knowledge nor enthusiasm, which was proven again in October 2005 in Palm Springs

    Railing Systems for Use on Timber Deck Bridges

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    Bridge railing systems in the United States have historically been designed based on static load criteria given in the AASHTO Standard Specifications for Highway Bridges. In the past decade, full-scale vehicle crash testing has been recognized as a more appropriate and reliable method of evaluating bridge railing acceptability. In 1989, AASHTO published the Guide Specifications for Bridge Railings, which gave the recommendations and procedures to evaluate bridge rails by full-scale vehicle crash testing. In 1993, the National Cooperative Highway Research Program (NCHRP) published Report 350: Recommended Procedures for the Safety Performance Evaluation of Highway Features, which provided criteria for evaluating longitudinal barriers. Based on these specifications, a cooperative research program was initiated between the University of Nebraska-Lincoln and the Forest Products Laboratory, and later the FHWA, to develop and crash test 11 bridge rails for wood deck bridges. The research that resulted in successful development and testing of 11 bridge railing systems for longitudinally and transversely laminated wood bridge decks in accordance with AASHTO Performance Level 1 and 2 (PL-1 and PL-2) requirements and Test Levels 1, 2, and 4 (TL-1, TL-2, and TL-4) requirements of NCHRP Report 350 are described here

    Our Conversations - Where Are We Now In Our Lives?

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    This article is about a series of conversations between three colleagues, previously significantly involved in community education practice and is the influences of their experiences, values and beliefs when encountering leaving full-time employment.  The paper, which has been developed from transcripts of these dialogue sessions, contains some extracts and views from each of the participants about life and work, and suggests a re-visioning of retirement

    Unlikely Alliances and Their Implications for Resource Management in the American West

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    Collaborative, or participatory governance is an increasingly common means of addressing natural resource issues, especially in the American West where patchworks of public, private, and tribal interests characterize the region’s resources. In this context, unlikely alliances, or partnerships among diverse actors who have historically been at odds, have a growing potential to shape social and ecological outcomes, for better or worse. While these unlikely alliances have received greater attention in recent years, relatively little research has worked to synthesize the concept across diverse contexts and disciplines. Based on a review of the literature on unlikely alliances in natural resource governance, we develop a framework that synthesizes the individual motivations and contextual factors that influence their formation, as well as the social and ecological outcomes that they create. We use this framework to analyze six illustrative cases of unlikely alliances. Our analysis of these cases suggests that unlikely alliances in the American West are likely to arise in the presence of a crisis, when appropriate leadership is present, when some of the actors have interacted effectively in the past, and when actors need to pool resources. The cases also illustrate some common outcomes, including environmental improvement, transformation of social networks, policy change, and shifts in power relationships. We discuss the implications of unlikely alliances for the social-ecological future of the American West. Our paper highlights the role of unlikely alliances in shaping patterns of natural resource governance, and provides a focus for further research in this realm

    Longitudinal analysis of sleep in relation to BMI and body fat in children: the FLAME study

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    Objectives To determine whether reduced sleep is associated with differences in body composition and the risk of becoming overweight in young children
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