718 research outputs found

    Networked Families

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    Presents survey results on the use of the Internet and ownership of cell phones and computers, by household type. Examines how technology ownership affects the frequency, form, purpose, and quality of communications among family members and friends

    A transdisciplinary approach to a conservation crisis: a case study of the Eurasian curlew (Numenius arquata) in Ireland

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    In this article, we build on a growing literature of examples of transdisciplinary approaches to illustrate the catalysts and outcomes of a stakeholder‐driven process to conservation practice. We illustrate this using the case of one of Europe's most rapidly declining bird species, the Eurasian curlew (Numenius arquata ). As part of the response to its continuing decline, a stakeholder‐driven workshop was held in Ireland in November 2016, bringing together over 80 stakeholders from a range of governmental, non‐governmental, and private organizations responsible for or interested in curlew conservation and management. This innovative workshop sought to formulate ideas and support the implementation of actions from stakeholders themselves on how to halt further losses of curlews, within the current legislative framework. Four years on, many of the short‐ and medium‐term actions identified during the workshop have been implemented jointly by stakeholders. However, curlew recovery will require continued communication and meaningful engagement with all relevant stakeholders together with increased government support underpinned by increased public awareness and ownership of the curlew's plight. Ultimately, many stakeholders will measure the success of curlew conservation in Ireland by the long‐term viability of the breeding population

    Lab-On-A-Chip for Oral Cancer Screening and Diagnosis

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    Oral squamous cell carcinoma (OSCC) is a disfiguring and deadly cancer. Despite advances in therapy, many patients continue to face a poor prognosis. Early detection is an important factor in determining the survival of patients with OSCC. No accurate, cost-efficient, and reproducible method exists to screen patients for OSCC. As a result, many patients are diagnosed at advanced stages of the disease. Early detection would identify patients, facilitating timely treatment and close monitoring. Mass screening requires a rapid oral cancer diagnostic test that can be used in a clinical setting. Current diagnostic techniques for OSCC require modern laboratory facilities, sophisticated equipment, and elaborate and lengthy processing by skilled personnel. The lab-on-chip technology holds the promise of replacing these techniques with miniaturized, integrated, automated, inexpensive diagnostic devices. This article describes lab-on-chip devices for biomarker-based identification of oral cancer. Similar methods can be employed for the screening of other types of cancers

    Particulate methane monooxygenase contains only mononuclear copper centers

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    Bacteria that oxidize methane to methanol are central to mitigating emissions of methane, a potent greenhouse gas. The nature of the copper active site in the primary metabolic enzyme of these bacteria, particulate methane monooxygenase (pMMO), has been controversial owing to seemingly contradictory biochemical, spectroscopic, and crystallographic results. We present biochemical and electron paramagnetic resonance spectroscopic characterization most consistent with two monocopper sites within pMMO: one in the soluble PmoB subunit at the previously assigned active site (CuB) and one ~2 nanometers away in the membrane-bound PmoC subunit (CuC). On the basis of these results, we propose that a monocopper site is able to catalyze methane oxidation in pMMO

    Aligning Retrograde Nuclear Cluster Orbits with an Active Galactic Nucleus Accretion Disc

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    Stars and stellar remnants orbiting a supermassive black hole (SMBH) can interact with an active galactic nucleus (AGN) disc. Over time, prograde orbiters (inclination i<90∘i<90^{\circ}) decrease inclination, as well as semi-major axis (aa) and eccentricity (ee) until orbital alignment with the gas disc ("disc capture"). Captured stellar-origin black holes (sBH) add to the embedded AGN population which drives sBH-sBH mergers detectable in gravitational waves using LIGO-Virgo-KAGRA (LVK) or sBH-SMBH mergers detectable with LISA (Laser Interferometer Space Antenna). Captured stars can be tidally disrupted by sBH or the SMBH or rapidly grow into massive 'immortal' stars. Here, we investigate the behaviour of polar and retrograde orbiters (i≄90∘i \geq 90^{\circ}) interacting with the disc. We show that retrograde stars are captured faster than prograde stars, flip to prograde (i<90∘i<90^{\circ}) during capture and decrease aa dramatically towards the SMBH. For sBH, we find a critical angle iret∌113∘i_{\rm ret} \sim 113^{\circ}, below which retrograde sBH decay towards embedded prograde orbits (i→0∘i \rightarrow 0^{\circ}), while for io>ireti_{\rm o}>i_{\rm ret} sBH decay towards embedded retrograde orbits (i→180∘i \rightarrow 180^{\circ}). sBH near polar orbits (i∌90∘i \sim 90^{\circ}) and stars on nearly embedded retrograde orbits (i∌180∘i \sim 180^{\circ}) show the greatest decreases in aa. Whether a star is captured by the disc within an AGN lifetime depends primarily on disc density, and secondarily on stellar type and initial aa. For sBH, disc capture time is longest for polar orbits, low mass sBH and lower density discs. Larger mass sBH should typically spend more time in AGN discs, with implications for the embedded sBH spin distribution.Comment: 10 pages, 7 figures, 1 table; submitted to MNRA

    EFFECTS OF MANAGEMENT PRACTICES ON GRASSLAND BIRDS: HORNED LARK

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    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 4,000 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species’ nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species’ response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species’ breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management is posted at the Web site mentioned below

    Longitudinal associations of away-from-home eating, snacking, screen time, and physical activity behaviors with cardiometabolic risk factors among Chinese children and their parents

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    Background: Little is known about intergenerational differences in associations of urbanization-related lifestyle behaviors with cardiometabolic risk factors in children and their parents in rapidly urbanizing China

    Associations between age, cohort, and urbanization with SBP and DBP in China: a population-based study across 18 years

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    Little is known about whether large-scale environmental changes, such as those seen with urbanization, are differentially associated with systolic versus diastolic blood pressure, and whether those changes vary by birth cohort
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