Stigma salience increases loneliness among ethnic minorities

This is the final version. Available on open access from Wiley via the DOI in this recordData availability statement: The datasets generated during the current study are available from the corresponding author upon reasonable request.Research shows that ethnic minorities are at increased risk of loneliness compared to the general population of the United Kingdom. We hypothesized that stigma salience increases loneliness among ethnic minorities, conducting two experimental studies with ethnic minorities (Study 1: N = 134, Study 2: N = 267) in which participants were randomly assigned to a stigma salience (recalling a personal experience of discrimination based upon ethnicity) or control condition (recalling a past meal in Study 1 and the experience of reading a book in Study 2). Across these two studies, we demonstrated that stigma salience consistently increased selfreported loneliness relative to the control conditions. Study 1 additionally showed evidence for an indirect effect of stigma salience on loneliness through feelings of anxiety. Study 2 replicated the effect of self-relevant (but not non-self-relevant) stigma salience on loneliness and provided suggestive evidence for a more specific indirect effect through identity-related social anxiety.European Unio

Toward a more relational model of sexual minority identity concealment

This is the final version. Available from Springer via the DOI in this record.

Social relationship experiences of transgender people and their relational partners: A meta-synthesis

This is the final version. Available on open access from Elsevier via the DOI in this recordRationale: Social relationships are important in bolstering health and well-being for everyone in the general population. For transgender people, strong supportive social relationships may be paramount to their overall health and well-being due to their marginalised status in society. Objective: This review aimed to investigate what is currently known about social relationship experiences of transgender people and their relational partners (e.g., family members, romantic partners). Method: Thirty-nine qualitative papers were extracted from Web of Science, Scopus, Cochrane, and PubMed that related to social relationships of transgender people. These papers were analysed via a qualitative meta-synthesis. Results: Forty-nine second order themes were identified, initially organised into relational partner clusters (e.g., family, friends, work colleagues) for specific phenomena, then these were synthesized into five overarching conceptual themes: (1) Development of relationships through transition and beyond, (2) Coping strategies of transgender people and their relational partners, (3) Reciprocal support in social relationships, (4) Stigma enacted and ameliorated interpersonally, and (5) Influence of stigma on social health and well-being. Discussion and conclusions: These overarching themes show the potential characteristics that assist in the health-buffering role of social relationships for transgender people and their relational partners. Of particular note, stigma was reported as a common negative experience by transgender people and their relational partners, and open communicative social relationships had positive effects on self-conceptualisations of identity, which were inferred to protect against the damaging effects of stigma. We discuss the various implications and applications of this meta-synthesis to future research and clinical settings as well as how it can inform healthcare policy to support transgender people.Devon Partnership NHS Trus

Identity-Related Factors Protect Well-Being against Stigma for Transgender and Gender Non-Conforming People

This is the final version. Available on open access from Springer via the DOI in this recordAvailability of data and material: The materials and anonymized data for this study are available upon request to the corresponding author.Code availability: The code for analyses conducted in this work are available upon request to the corresponding author.Relatively little is known about identity-related resilience factors associated with well-being among transgender and gender non-conforming (TGNC) people. Drawing upon theory on stigma-related stress and resilience and work examining group identification as a buffer against discrimination, the aim of the current study was to model perceived discrimination, transgender identification, and gender identity affirmation as predictors of well-being for TGNC people. We also tested whether the positive association between gender identity affirmation and well-being might be explained by the benefits affirmation has for individual self-concept clarity. Participants were 105 TGNC individuals (42% transgender male, 39% transgender female, 19% other gender non-conforming [e.g., non-binary]) recruited through online forums and support groups in the United Kingdom and North America who completed an online survey including self-report measures of key constructs. Results from structural equation models demonstrated that: (1) experiences of discrimination were associated with lower well-being overall, but having a stronger transgender identity moderated this association; (2) after adjustment for discrimination and transgender identification, experiences of gender identity affirmation were independently associated with greater well-being for TGNC people. Secondary analyses demonstrated that gender identity affirmation was linked to well-being through reinforcing a strong, internalized sense of clarity about individual self-concept. Results are discussed in terms of the implications for TGNC health and well-being, particularly with regards to the need for supportive, identity-affirming social environments.University of Exete

Frequency and Mental Health Consequences of Microaggressions Experienced in the Day-to-Day Lives of Transgender and Gender Diverse People

This is the author accepted manuscript.Method. The current daily diary study investigated the frequency and types of microaggressions experienced by TGD people as well as their concurrent and prospective associations with mental health and well-being. Daily surveys measuring microaggressions, gender dysphoria, depressive and anxious symptoms, and self-esteem over the last 24 hours were completed by TGD participants (N = 39) across 10 consecutive days (total of 351 diary entries). Results. Seventy-four percent of participants experienced some form of microaggression within the 10-day study period, reporting an average of 1 microaggression approximately every other day. Microaggressions were associated with greater feelings of gender dysphoria, depressive and anxious symptoms, and lower self-esteem at the between-person level, while evidence for within-person effects was mixed (with some evidence for significant associations with gender dysphoria and self-esteem for specific microaggression domains). No evidence for prospective associations between microaggressions and mental health were found in the current study. Discussion. Given the frequency of experiences of microaggressions in TGD people’s daily lives, particularly misuse of pronouns, it is critical that healthcare providers are aware of potential effects on mental health and well-being.European Research Council (ERC

Associations of vitamin D pathway genes with circulating 25-hydroxyvitamin-D, 1,25-dihydroxyvitamin-D, and prostate cancer:a nested case-control study

Vitamin D pathway single nucleotide polymorphisms (SNPs) are potentially useful proxies for investigating whether circulating vitamin D metabolites [total 25-hydroxyvitamin-D, 25(OH)D; 1,25-dihydroxyvitamin, 1,25(OH)2D] are causally related to prostate cancer. We investigated associations of sixteen SNPs across seven genes with prostate-specific antigen-detected prostate cancer

Extended Tower Number Field Sieve with Application to Finite Fields of Arbitrary Composite Extension Degree

We propose a generalization of exTNFS algorithm recently introduced by Kim and Barbulescu (CRYPTO 2016). The algorithm, exTNFS, is a state-of-the-art algorithm for discrete logarithm in $\mathbb{F}_{p^n}$ in the medium prime case, but it only applies when $n=\eta\kappa$ is a composite with nontrivial factors $\eta$ and $\kappa$ such that $\gcd(\eta,\kappa)=1$. Our generalization, however, shows that exTNFS algorithm can be also adapted to the setting with an arbitrary composite $n$ maintaining its best asymptotic complexity. We show that one can solve discrete logarithm in medium case in the running time of $L_{p^n}(1/3, \sqrt[3]{48/9})$ (resp. $L_{p^n}(1/3, 1.71)$ if multiple number fields are used), where $n$ is an \textit{arbitrary composite}. This should be compared with a recent variant by Sarkar and Singh (Asiacrypt 2016) that has the fastest running time of $L_{p^n}(1/3, \sqrt[3]{64/9})$ (resp. $L_{p^n}(1/3, 1.88)$) when $n$ is a power of prime 2. When $p$ is of special form, the complexity is further reduced to $L_{p^n}(1/3, \sqrt[3]{32/9})$. On the practical side, we emphasize that the keysize of pairing-based cryptosystems should be updated following to our algorithm if the embedding degree $n$ remains composite

A Community Study of Factors Related to Poorly Controlled Asthma among Brazilian Urban Children

BACKGROUND: Asthma constitutes a serious public health problem in many regions of the world, including the city of Salvador, State of Bahia-Brazil. The purpose of this study was to analyse the factors associated with poor asthma control. METHODOLOGY/PRINCIPAL FINDINGS: Two definitions were used for asthma: 1) wheezing in the last 12 months; 2) wheezing in the last 12 months plus other asthma symptoms or asthma diagnosis ever. The definition of poorly controlled asthma was: at least one reported hospitalisation due to asthma and/or high frequency of symptoms, in the last year. Children with poorly controlled asthma (N = 187/374) were compared with wheezing children with controlled asthma regarding age, gender, atopy, parental asthma, rhinitis, eczema, exposure to second hand tobacco smoke, presence of moulds, pets and pests in the house, helminth infections and body mass index. Crude and logistic regression adjusted odds ratios were used as measures of association. There was a higher proportion of poorly controlled asthma among children with eczema (OR = 1.55; 95% CI 1.02; 2.37). The strength of the association was greater among children with eczema and rhinitis (42.6%, 53.4% and 57.7%, respectively, in children who had no rhinitis nor eczema, had only one of those, and had both (p = 0.02 for trend test). The presence of mould in the houses was inversely associated with poorly controlled asthma (OR = 0.54; 95% CI 0.34; 0.87). CONCLUSIONS/SIGNIFICANCE: Our results indicate an association between eczema and poor asthma control in this environment, but emphasize the role of various other individual and environmental factors as determinants of poor control