4 research outputs found
An Analysis of C-Reactive Protein, Procalcitonin, and D-Dimer in Pre-Eclamptic Patients
PubMedID: 22783989Problem: The aim of this study was to evaluate serum procalcitonin (PCT), C-reactive protein (CRP), and plasma D-Dimer levels in mild and severe pre-eclampsia. Method of study: Serum PCT, CRP, and D-Dimer levels were analyzed in 64 cases with pre-eclampsia as the study group and 33 healthy pregnant women in the third trimester as the control group. Pre-eclamptic group consisted of mild (n = 31) and severe pre-eclamptic subgroup (n = 33). Laboratory results were compared between the groups and diagnostic usefulness of these parameters were evaluated. Results: PCT, CRP, and D-Dimer levels were significantly higher in study group than the control group (P = 0.001). PCT, CRP, and D-Dimer were significantly higher in the patients with severe pre-eclampsia than mild pre-eclampsia. There were significant positive correlations between these markers and mean arterial pressure (MAP). Logistic regression analysis using the control and pre-eclampsia group showed that higher PCT (OR, 15.68; 95%-CI, 3.15-78.10), CRP (OR, 14.29; 95%-CI, 3.08-66.34), and D-Dimer levels (OR, 4.97; 95%-CI, 1.22-20.29) were found to be risk factors significantly associated with pre-eclampsia. Conclusions: This study results confirm that evidence of a possible exaggerated systemic inflammatory response in pre-eclampsia especially in severe pre-eclampsia. © 2012 John Wiley & Sons A/S
Immunization status in chronic obstructive pulmonary disease: A multicenter study from Turkey
OBJECTIVE: The purpose of this study is to detect the prevalence and the factors associated with influenza and pneumococcal vaccination and outcomes of vaccination during 2013-2014 season in patients with chronic obstructive pulmonary disease (COPD) in Turkey
Immunization status in chronic obstructive pulmonary disease: A multicenter study from Turkey
OBJECTIVE: The purpose of this study is to detect the prevalence and the
factors associated with influenza and pneumococcal vaccination and
outcomes of vaccination during 2013-2014 season in patients with chronic
obstructive pulmonary disease (COPD) in Turkey.
METHODS: This was a multicenter retrospective cohort study performed in
53 different centers in Turkey.
RESULTS: During the study period, 4968 patients were included. COPD was
staged as GOLD 1-2-3-4 in 9.0\%, 42.8\%, 35.0\%, and 13.2\% of the
patients, respectively. Influenza vaccination rate in the previous year
was 37.9\%; and pneumococcus vaccination rate, at least once during in a
life time, was 13.3\%. Patients with older age, higher level of
education, more severe COPD, and comorbidities, ex-smokers, and patients
residing in urban areas had higher rates of influenza vaccination.
Multivariate logistic regression analysis showed that advanced age,
higher education levels, presence of comorbidities, higher COPD stages,
and exacerbation rates were associated with both influenza and
pneumococcal vaccination. The number of annual physician/outpatient
visits and hospitalizations due to COPD exacerbation was 2.73 +/- 2.85
and 0.92 +/- 1.58 per year, respectively. Patients with older age, lower
education levels, more severe COPD, comorbid diseases, and lower body
mass index and patients who are male and are residing in rural areas and
vaccinated for influenza had significantly higher rates of COPD
exacerbation.
CONCLUSIONS: The rates of influenza and pneumococcal vaccination in COPD
patients were quite low, and the number of annual physician/outpatient
visits and hospitalizations due to COPD exacerbation was high in Turkey.
Advanced age, higher education levels, comorbidities, and higher COPD
stages were associated with both influenza and pneumococcal vaccination