5,073 research outputs found
Universal transloader moves delicate equipment without stress
Transloader moves delicate or heavy items over irregular surfaces without transmitting stress to the load. The loader is supported on three pivot points which produce a wrap free base. The base is supported by an artificial four-wheel frame
Interacting vector fields in Relativity without Relativity
Barbour, Foster and \'{O} Murchadha have recently developed a new framework,
called here {\it{the 3-space approach}}, for the formulation of classical
bosonic dynamics. Neither time nor a locally Minkowskian structure of spacetime
are presupposed. Both arise as emergent features of the world from
geodesic-type dynamics on a space of 3-dimensional metric--matter
configurations. In fact gravity, the universal light cone and Abelian gauge
theory minimally coupled to gravity all arise naturally through a single common
mechanism. It yields relativity -- and more -- without presupposing relativity.
This paper completes the recovery of the presently known bosonic sector within
the 3-space approach. We show, for a rather general ansatz, that 3-vector
fields can interact among themselves only as Yang--Mills fields minimally
coupled to gravity.Comment: Replaced with final version accepted by Classical and Quantum Gravity
(14 pages, no figures
The geometry of the Barbour-Bertotti theories I. The reduction process
The dynamics of interacting particles is investigated in the
non-relativistic context of the Barbour-Bertotti theories. The reduction
process on this constrained system yields a Lagrangian in the form of a
Riemannian line element. The involved metric, degenerate in the flat
configuration space, is the first fundamental form of the space of orbits of
translations and rotations (the Leibniz group). The Riemann tensor and the
scalar curvature are computed by a generalized Gauss formula in terms of the
vorticity tensors of generators of the rotations. The curvature scalar is
further given in terms of the principal moments of inertia of the system. Line
configurations are singular for . A comparison with similar methods in
molecular dynamics is traced.Comment: 15 pages, to appear in Classical and Quantum Gravit
The geometry of the Barbour-Bertotti theories II. The three body problem
We present a geometric approach to the three-body problem in the
non-relativistic context of the Barbour-Bertotti theories. The Riemannian
metric characterizing the dynamics is analyzed in detail in terms of the
relative separations. Consequences of a conformal symmetry are exploited and
the sectional curvatures of geometrically preferred surfaces are computed. The
geodesic motions are integrated. Line configurations, which lead to curvature
singularities for , are investigated. None of the independent scalars
formed from the metric and curvature tensor diverges there.Comment: 16 pages, 2 eps figures, to appear in Classical and Quantum Gravit
Leptons, quarks, and their antiparticles from a phase-space perspective
It is argued that antiparticles may be interpreted in macroscopic terms
without explicitly using the concept of time and its reversal. The appropriate
framework is that of nonrelativistic phase space. It is recalled that a quantum
version of this approach leads also, alongside the appearance of antiparticles,
to the emergence of `internal' quantum numbers identifiable with weak isospin,
weak hypercharge and colour, and to the derivation of the Gell-Mann-Nishijima
relation, while simultaneously offering a preonless interpretation of the
Harari-Shupe rishon model. Furthermore, it is shown that - under the assumption
of the additivity of canonical momenta - the approach entails the emergence of
string-like structures resembling mesons and baryons, thus providing a
different starting point for the discussion of quark unobservability.Comment: Talk given at Fifth Int. Workshop DICE2010 Space-Time-Matter,
Castiglioncello, Italy, September 13-17, 201
Towards the Unification of Gravity and other Interactions: What has been Missed?
Faced with the persisting problem of the unification of gravity with other
fundamental interactions we investigate the possibility of a new paradigm,
according to which the basic space of physics is a multidimensional space
associated with matter configurations. We consider general
relativity in . In spacetime, which is a 4-dimensional subspace of
, we have not only the 4-dimensional gravity, but also other
interactions, just as in Kaluza-Klein theories. We then consider a finite
dimensional description of extended objects in terms of the center of mass,
area, and volume degrees of freedom, which altogether form a 16-dimensional
manifold whose tangent space at any point is Clifford algebra Cl(1,3). The
latter algebra is very promising for the unification, and it provides
description of fermions.Comment: 11 pages; Talk presented at "First Mediterranean Conference on
Classical and Quantum Gravity", Kolymbari, Crete, Greece, 14-18 September
200
Scale-invariant gravity: Spacetime recovered
The configuration space of general relativity is superspace - the space of
all Riemannian 3-metrics modulo diffeomorphisms. However, it has been argued
that the configuration space for gravity should be conformal superspace - the
space of all Riemannian 3-metrics modulo diffeomorphisms and conformal
transformations. Recently a manifestly 3-dimensional theory was constructed
with conformal superspace as the configuration space. Here a fully
4-dimensional action is constructed so as to be invariant under conformal
transformations of the 4-metric using general relativity as a guide. This
action is then decomposed to a (3+1)-dimensional form and from this to its
Jacobi form. The surprising thing is that the new theory turns out to be
precisely the original 3-dimensional theory. The physical data is identified
and used to find the physical representation of the theory. In this
representation the theory is extremely similar to general relativity. The
clarity of the 4-dimensional picture should prove very useful for comparing the
theory with those aspects of general relativity which are usually treated in
the 4-dimensional framework.Comment: Replaced with final version: minor changes to tex
Sickness certification system in the United Kingdom: qualitative study of views of general practitioners in Scotland
Objectives: To explore how general practitioners operate the sickness certification system, their views on the system, and suggestions for change.
Design: Qualitative focus group study consisting of 11 focus groups with 67 participants.
Setting: General practitioners in practices in Glasgow, Tayside, and Highland regions, Scotland.
Sample: Purposive sample of general practitioners, with further theoretical sampling of key informant general practitioners to examine emerging themes.
Results: General practitioners believed that the sickness certification system failed to address complex, chronic, or doubtful cases. They seemed to develop various operational strategies for its implementation. There appeared to be important deliberate misuse of the system by general practitioners, possibly related to conflicts about roles and incongruities in the system. The doctor-patient relationship was perceived to conflict with the current role of general practitioners in sickness certification. When making decisions about certification, the general practitioners considered a wide variety of factors. They experienced contradictory demands from other system stakeholders and felt blamed for failing to make impossible reconciliations. They clearly identified the difficulties of operating the system when there was no continuity of patient care. Many wished either to relinquish their gatekeeper role or to continue only with major changes.
Conclusions: Policy makers need to recognise and accommodate the range and complexity of factors that influence the behaviour of general practitioners operating as gatekeepers to the sickness certification system, before making changes. Such changes are otherwise unlikely to result in improvement. Models other than the primary care gatekeeper model should be considered
ATP allosterically activates the human 5-lipoxygenase molecular mechanism of arachidonic acid and 5(S)-hydroperoxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid.
5-Lipoxygenase (5-LOX) reacts with arachidonic acid (AA) to first generate 5(S)-hydroperoxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid [5(S)-HpETE] and then an epoxide from 5(S)-HpETE to form leukotriene A4, from a single polyunsaturated fatty acid. This work investigates the kinetic mechanism of these two processes and the role of ATP in their activation. Specifically, it was determined that epoxidation of 5(S)-HpETE (dehydration of the hydroperoxide) has a rate of substrate capture (Vmax/Km) significantly lower than that of AA hydroperoxidation (oxidation of AA to form the hydroperoxide); however, hyperbolic kinetic parameters for ATP activation indicate a similar activation for AA and 5(S)-HpETE. Solvent isotope effect results for both hydroperoxidation and epoxidation indicate that a specific step in its molecular mechanism is changed, possibly because of a lowering of the dependence of the rate-limiting step on hydrogen atom abstraction and an increase in the dependency on hydrogen bond rearrangement. Therefore, changes in ATP concentration in the cell could affect the production of 5-LOX products, such as leukotrienes and lipoxins, and thus have wide implications for the regulation of cellular inflammation
The Definition of Mach's Principle
Two definitions of Mach's principle are proposed. Both are related to gauge
theory, are universal in scope and amount to formulations of causality that
take into account the relational nature of position, time, and size. One of
them leads directly to general relativity and may have relevance to the problem
of creating a quantum theory of gravity.Comment: To be published in Foundations of Physics as invited contribution to
Peter Mittelstaedt's 80th Birthday Festschrift. 30 page
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