The identification of multiple thrombophilic risk factors in an infant with cerebrovascular accident

We found 1 article: Rev Neurol. 2005 Apr 16-30;40(8):479-81. [The identification of multiple thrombophilic risk factors in an infant with cerebrovascular accident] [Article in Spanish] Neves J, Costa E, Branca R, Carrilho I, Barbot J, Barbot C. Servicio de Hematología, Hospital de Crianças Maria Pia, 4050-111 Porto, Portugal. Abstract INTRODUCTION: Neonatal stroke (NNS) incidence appears to be increasing over the last years. This is believed to be a consequence of diagnostic accuracy rather than a real amplification of this entity. Nowadays, NNS incidence is estimated to be 1:4000 full newborns. CASE REPORT: Child with left middle cerebral artery territory infarction in which several thromboembolic risk factors were documented both in the child (neonatal sepsis and factor V Leiden) and his mother (lupus anticoagulant, pre-eclampsy and factor V Leiden). CONCLUSIONS: This case supports the increasing evidence in recent reports that association of multiple prothrombotic risk factors (maternal and foetal) is present in NNS genesis. This way the authors agree that wide prothrombotic study may be of crucial interest in identifying subjacent thrombophilic disease, even when an exogenous risk factor is present. PMID: 15861329 [PubMed - indexed for MEDLINE

Molecular characterization of a portuguese patient with Shwachman-Diamond syndrome

Shwachman-Diamond syndrome (SDS) a rare autosomal recessive disorder described first time 1964 (1), is characterized by the association of exocrine pancreatic and bone marrow dysfunction. Other systemic findings (skeletal, liver and psychomotor) or problems secondary to bone marrow dysfunction may also be detected (1–4). Intermittent or persistent neutropenia is the most common hematologic finding, but anemia and thrombocytopenia are present in approximately 40% of the patients (1–4). In 2002, fine mapping identified the locus for SDS in band 7q11. More recently Boocock et al. (5) identified 18 positional candidate genes in this locus and examined eight of them for occurrence SDS-associated changes. They found alterations only in a previously uncharacterised gene. This gene, designated SBDS (Shwachman- Bodian-Diamond syndrome), is composed of five exons spanning 7.9Kb. The authors also described a pseudogene (SBDSP) with 97% homology to SBDS (5)

Victorian Influence on \u3cem\u3eBeauty and the Beast\u3c/em\u3e

This essay examines a unique publication of the well-known Beauty and the Beast fairy tale. W.B. Conkey Company’s adaptation of Beauty and the Beast demonstrates the influence of Victorian culture on children’s literature (1897). An in-depth analysis of the cultural and historical context of the publication uncovers new meaning in the lost text. This three-part analysis discusses norms of Victorian courtship, explains Victorian literary elements, and applies these cultural contexts to textual analysis. This lens highlights W.B. Conkey Company’s tailored message to a young Victorian audience

Second order sliding mode and adaptive observer for synchronization of a chaotic system: a comparative study

International audienceIn this paper two nonlinear observers for a chaotic system are compared. Moreover, the left invertible problem and the observability singularity are discussed. Thus, after a presentation of both observers, a comparison of the two proposed methods and a discussion are done on the basis of simulations results. The last part highlights the fact that the finite time observer is more sensible to the singularity observations, but less sensible to parameter uncertainties and noise in the output of the system

Andrezé – Échangeur de la Croix Barbot

Les sondages réalisés à la Croix Barbot ont mis au jour un fossé large de 2 m, ainsi que plusieurs fosses. Le dernier comblement de la fosse la plus importante (2,40 m sur 4,80 m) a fourni un mobilier attribuable aux ve-ive s. av. J.-C. La prospection pédestre menée à proximité des sondages a livré un matériel céramique comparable. Fig. 1 – Céramique de l’âge du Fer Dessins : Inrap

When the history of property rights encounters the Economics of Convention: some open questions starting from European history

"The aim of this article is to analyse the relationships between law and conventions with regards to an issue still little explored in the perspective of the Economics of Convention (EC): the history of property rights. Focusing on Continental Europe, the main key points of the recent debate on property rights’ long-term evolution will be outlined, which are basically developed along the lines of the New Historical Institutionalism theories (NHI). After discussing the NHI approach to legal institutions, it will be demonstrated how even the soundest criticisms to this approach do not exhaust the list of open questions on the relationship between conventions and property rights. These questions are mainly related to the problems of uncertainty and to the connection between property rules, their interpretation and their legitimization. By defining these questions, it will be shown how the EC perspective could contribute to providing a more complex interpretation -and therefore historically more pertinent- of the long-term changes of one of the major legal institutions of western capitalism." (author's abstract

Samīra ‘Azzām, Pioneer of the Palestinian Short Story

Samīra ‘Azzām (1927-1967) es la primera mujer palestina en alcanzar fama por su maestría para escribir relato corto. Tras revisar su vida, que pasó en el exilio desde 1948, se resumen el contenido de sus colecciones de relatos, sus principales líneas temáticas y sus traducciones al árabe de obras de la literatura universal. Pero la parte principal de este trabajo se va a dedicar a describir y comentar algunos de sus relatos más destacados.Samīra ‘Azzām (1927-1967) is the first Palestinian woman to achieve fame for her mastery to write short stories. After reviewing her life, she spent in exile since 1948, the content of her collections of stories, its main thematic lines, and her Arabic translations from works of world literature are summarized. But the chief part of this paper will be dedicated to describe and discuss some of its most prominent short stories

A new case of (TA)8 allele in the UGT1A1 gene promoter in a caucasian girl with Gilbert' syndrome

The authors describe a 5-year-old Caucasian girl, referred to their hospital for evaluation of an unconjugated hyperbilirubinemia (57.9 μmol/L) detected from blood analysis during an episode of fever. The molecular analysis of the TATA-box region of the UGT1A1 gene revealed that the patient was a compound heterozygote for two insertions, one TA and the other TATA [(TA)7 /(TA)8 ]. This is the first case of (TA)8 allele found in a Portuguese Caucasian patient and the third found in the literature