Conhecimento Tradicional E Usos De Caryocar Brasiliense Cambess. (pequi) Por Quilombolas De Minas Gerais, Brasil: Subsídios Para O Manejo Sustentável

Local knowledge of biodiversity has been applied in support of research focused on utilizing and management of natural resources and promotion of conservation. Among these resources, Pequi (Caryocar brasiliense Cambess.) is important as a source of income and food for communities living in the Cerrado biome. In Pontinha, a “quilombola” community, which is located in the central region of State of Minas Gerais, Brazil, an ethnoecological study about Pequi was conducted to support initiatives for generating income for this community. Data were collected through semi-structured interviews, participant observation, and crossing. The most relevant uses of Pequi were family food (97%), soap production (67%), oil production (37%), medical treatments (17%), and trade (3%). Bees were the floral visitors with the highest Salience Index (S=0.639). Among frugivores that feed on unfallen fruits, birds showed a higher Salience (S=0.359) and among frugivores who use fallen fruits insects were the most important (S=0.574). Borers (folivorous caterpillars) that attack trunks and roots were the most common pests cited. According to the respondents, young individuals of Pequi are the most affected by fire due to their smaller size and thinner bark. Recognition of the cultural and ecological importance of Pequi has mobilized the community, which has shown interest in incorporating this species as an alternative source of income. © 2016, Instituto Internacional de Ecologia. All rights reserved.762511519FAPEMIG, Fundação de Amparo à Pesquisa do Estado de Minas Gerai

Influence of the size and amount of cork particles on the toughness of a structural adhesive

The inclusion of particles (nano or micro) is a method to improve the mechanical properties such as toughness of structural adhesives. Structural adhesives are known for their high strength and stiffness but also for their low ductility and toughness. There are many processes described in the literature to increase the toughness, being one of the most common the use of rubber particles. In the present study, natural micro particles of cork are used with the objective to increase the toughness of a brittle epoxy adhesive. The idea is for the cork particles to act like as a crack stopper leading to more energy absorption. The influence of the cork particle size and amount were studied. Particles of cork ranging from 38 to 250 µm were mixed in the epoxy adhesive Araldite 2020 from Huntsman. The amount of cork in the adhesive was varied between 1 and 5% in weight. Surface treatment (low pressure plasma) was applied to the cork powder to assess the effect of the interaction adhesive-cork with several degrees of adhesion

Co-activation of NF-κB and MYC renders cancer cells addicted to IL6 for survival and phenotypic stability

NF-κB and MYC are found co-deregulated in human B and plasma-cell cancers. In physiology, NF-κB is necessary for terminal B-to-plasma cell differentiation, whereas MYC repression is required. It is thus unclear if NF-κB/MYC co-deregulation is developmentally compatible in carcinogenesis and/or impacts cancer cell differentiation state, possibly uncovering unique sensitivities. Using a mouse system to trace cell lineage and oncogene activation we found that NF-κB/MYC co-deregulation originated cancers with a plasmablast-like phenotype, alike human plasmablastic-lymphoma and was linked to t(8;14)[MYC-IGH] multiple myeloma. Notably, in contrast to NF-κB or MYC activation alone, co-deregulation rendered cells addicted to IL6 for survival and phenotypic stability. We propose that conflicting oncogene-driven differentiation pressures can be accommodated at a cost in poorly-differentiated cancers. SIGNIFICANCE: Our studies improve the understanding of cancer pathogenesis by demonstrating that co-deregulation of NF-κB and MYC synergize in forming a cancer with a poorly-differentiated state. The cancers in the mouse system share features with human Plasmablastic lymphoma that has a dismal prognosis and no standard of care, and with t(8;14)[MYC-IGH] Multiple myeloma, which is in overall resistant to standard therapy. Notably, we found that NF-κB and MYC co-deregulation uniquely render cells sensitive to IL6 deprivation, providing a road-map for patient selection. Because of the similarity of the cancers arising in the compound mutant mouse model with that of human Plasmablastic lymphoma and t(8;14)[MYC-IGH] Multiple myeloma, this model could serve in preclinical testing to investigate novel therapies for these hard-to-treat diseases

Crescimento de pimentão em diferentes arranjos espaciais

The objective of this work was to evaluate the growth of green pepper cv. Atlantis under different spatial arrangements. Three spacing arrangements between double and simple planting rows (1.5x0.5 m, 1.6x0.4 m and 1.7x0.3 m) and four spacing distances between plants in the rows (0.2, 0.3, 0.4 and 0.5 m) combined in factorial scheme were evaluated. A randomized block design in split-plots divided in time with three replicates was used. The growth assessment was done in nine occasions, 14 days apart, and the first one was performed 14 days after transplanting (DAT). Leaf area (LA), leaf area index (LAI), dry masses of leaves (LDM), stem (SDM), fruit (FrDM) and total shoot (TDM); absolute growth rate (AGR), rates of net assimilation (NAR) and relative growth (RGR); and leaf area (LAR) and leaf mass (LWR) ratios were evaluated until 126 DAT. The changes in LA, RGR, LWR and LAR did not depend on row spacing, but spacing influenced LDM, SDM, FrDM and TDM, LAI and AGR. The increase in spacing reduces LAI and LAR, and increases LA, LDM, SDM, FrDM, TDM, AGR and NAR, but does not influence RGR and LWR.O objetivo deste trabalho foi avaliar o crescimento do pimentão cv. Atlantis sob diferentes arranjos espaciais. Foram avaliados três arranjos de espaçamentos entre fileiras duplas e fileiras simples de plantio (1,5x0,5, 1,6x0,4 e 1,7x0,3 m), e quatro espaçamentos entre plantas nas fileiras (0,2, 0,3, 0,4 e 0,5 m), combinados em esquema fatorial. Utilizou-se o delineamento de blocos ao acaso, com três repetições e parcelas subdivididas no tempo. A avaliação de crescimento foi realizada em nove épocas espaçadas em 14 dias, com a primeira avaliação realizada 14 dias após o transplantio (DAT). Até os 126 DAT, foram avaliados: área foliar (AF); índice de área foliar (IAF); massas secas de folhas (MSF), do caule (MSC), de frutos (MSFr) e do total da parte aérea (MST); taxa de crescimento absoluto (TCA), assimilatória líquida (TAL) e de crescimento relativo (TCR); e as razões de área foliar (RAF) e de massa foliar (RMF). As alterações em AF, TCR, RMF e RAF foram independentes do espaçamento entre fileiras que, no entanto, influenciou MSF, MSC, MSFr e MST, IAF e TCA. O aumento do espaçamento entre plantas reduz o IAF e a RAF e aumenta a AF, MSF, MSC, MSFr, MST, TCA e TAL, mas não influencia a TCR e RMF

Influence of the size and amount of cork particles on the toughness of a structural adhesive

The inclusion of particles (nano or micro) is a method to improve the mechanical properties such as toughness of structural adhesives. Structural adhesives are known for their high strength and stiffness but also for their low ductility and toughness. There are many processes described in the literature to increase the toughness, being one of the most common the use of rubber particles. In the present study, natural micro particles of cork are used with the objective to increase the toughness of a brittle epoxy adhesive. The idea is for the cork particles to act like as a crack stopper leading to more energy absorption. The influence of the cork particle size and amount were studied. Particles of cork ranging from 38 to 250 µm were mixed in the epoxy adhesive Araldite 2020 from Huntsman. The amount of cork in the adhesive was varied between 1 and 5% in weight. Surface treatment (low pressure plasma) was applied to the cork powder to assess the effect of the interaction adhesive-cork with several degrees of adhesion

Functionally graded adhesive joints using magnetic microparticles with a polyurethane adhesive

The present work focuses on using a recently proposed method to create functionally graded adhesive joints using a polyurethane adhesive and iron microparticles. Functionally graded joints were created with the application of a suitable magnetic field in the centre of the overlap region. This field is able to move the iron microparticles and create a tailored particle distribution. The main goal of this work was to create a particle concentration gradient that changes from particle rich in the middle of the overlap to poor in the ends. Consequentially, the stiffness of the resulting composite is made to vary along the bondline. A numerical simulation was performed to determine the optimal distance between the magnet and the adhesive layer as well as the application time of the external magnetic field. In order to assess the influence of the iron particles on the adhesive, different particle amounts were experimentally considered and two particles distributions were evaluated (uniform and graded distributions). The predicted particles trajectories were validated through a study of the single lap joint (SLJ) fracture surfaces, showing that the magnetic particles follow the magnetic field lines towards the middle of the overlap. Also, by observing the same fracture surfaces, the recently proposed method was validated, a non-uniform particle distribution. Finally, SLJs containing 1% of iron microparticles with a graded distribution were found to exhibit the best mechanical performance. Thus, this method has been demonstrated to be a viable technique to enhance the mechanical properties of bonded joints, leading to a more uniform stress distribution along the bondline