890 research outputs found

    The For-Profit Prison as Social Enterprise: Problems with Classification and Ethical Assessment

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    This article explores the problems presented to taxonomies and definitions of social enterprise by a specific kind of organization, for-profit prisons. While these organizations are often and rightly criticized for their performance, they are fundamentally social enterprises by many of the definitions and taxonomies offered in the literature. This analysis uses a naïve matrix for classifying social enterprise to outline the problems created by these ethically and socially challenged organizations

    A Monte Carlo Evaluation of the Application of Variance Partitioning to the Assessment of Construct-related Validity

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    The present study presents a Monte Carlo evaluation of the application of variance partitioning to the assessment of the construct-related validity of assessment center (AC) post exercise dimension ratings (PEDRs). Data was produced by creating sixteen population models representing a variety of AC models by varying dimension factor loadings, exercise factor loadings, dimension intercorrelations, and exercise intercorrelations. Analyses demonstrated that variance partitioning differentiated among all sixteen varieties of AC models. Variance partitioning also detected other sources of variance including person effects, person by dimension effects, and person by exercise effects. These findings suggest that variance partitioning may be a more appropriate method for analyzing AC multitrait-multimethod (MTMM) data instead of the traditional confirmatory factor analysis (CFA) method.  M.A

    Vps54 Regulates Lifespan and Locomotor Behavior in Adult Drosophila Melanogaster

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    Vps54 is an integral subunit of the Golgi-associated retrograde protein (GARP) complex, which is involved in tethering endosome-derived vesicles to the trans-Golgi network (TGN). A destabilizing missense mutation in Vps54 causes the age-progressive motor neuron (MN) degeneration, muscle weakness, and muscle atrophy observed in the wobbler mouse, an established animal model for human MN disease. It is currently unclear how the disruption of Vps54, and thereby the GARP complex, leads to MN and muscle phenotypes. To develop a new tool to address this question, we have created an analogous model in Drosophila by generating novel loss-of-function alleles of the fly Vps54 ortholog (scattered/scat). We find that null scat mutant adults are viable but have a significantly shortened lifespan. Like phenotypes observed in the wobbler mouse, we show that scat mutant adults are male sterile and have significantly reduced body size and muscle area. Moreover, we demonstrate that scat mutant adults have significant age-progressive defects in locomotor function. Interestingly, we see sexually dimorphic effects, with scat mutant adult females exhibiting significantly stronger phenotypes. Finally, we show that scat interacts genetically with rab11 in MNs to control age-progressive muscle atrophy in adults. Together, these data suggest that scat mutant flies share mutant phenotypes with the wobbler mouse and may serve as a new genetic model system to study the cellular and molecular mechanisms underlying MN disease

    Prayer as Interpersonal Coping in the Lives of Mothers with HIV

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    The spirituality of 22 mothers diagnosed with HIV was explored through face-to-face interviews and revealed that 95% of the mothers pray. Active prayers (e.g., talking to God by adoring, thanking, confessing, and supplicating) were more frequently reported than receptive prayers (e.g., quietly listening to God, being open, surrendering). Supplicatory or petitionary prayers for help and health were the most frequent type of prayer, and adoration was the least frequent. The majority of mothers in the sample perceived prayer as a positive coping mechanism associated with outcomes such as: support, positive attitude/affect, and peace. Overall, results supported expanding the boundary conditions of the interpersonal coping component of the Social Interaction Model (Derlega & Barbee, 1998) to include the spiritual dimension of prayer

    Interfacial Electronic Charge Transfer and Density of States in Short Period Cu/Cr Multilayers

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    Nanometer period metallic multilayers are ideal structures to investigate electronic phenomena at interfaces between metal films since interfacial atoms comprise a large atomic fraction of the samples. The Cu/Cr binary pair is especially suited to study the interfaces in metals since these elements are mutually insoluble, thus eliminating mixing effects and compound formation and the lattice mismatch is very small. This allows the fabrication of high structural quality Cu/Cr multilayers that have a structure which can be approximated in calculations based on idealized atomic arrangements. The electronic structure of the Cu and the Cr layers in several samples of thin Cu/Cr multilayers were studied using x-ray absorption spectroscopy (XAS). Total electron yield was measured and used to study the white lines at the Cu L{sub 2} and L{sub 3} absorption edges. The white lines at the Cu absorption edges are strongly related to the unoccupied d-orbitals and are used to calculate the amount of charge transfer between the Cr and Cu atoms in interfaces. Analysis of the Cu white lines show a charge transfer of 0.026 electrons/interfacial Cu atom to the interfacial Cr atoms. In the Cu XAS spectra we also observe a van Hove singularity between the L{sub 2} and L{sub 3} absorption edges as expected from the structural analysis. The absorption spectra are compared to partial density of states obtained from a full-potential linear muffin-tin orbital calculation. The calculations support the presence of charge transfer and indicate that it is localized to the first two interfacial layers in both Cu and Cr

    Mission Design and Optimal Asteroid Deflection for Planetary Defense

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    Planetary defense is a topic of increasing interest for many reasons, which has been mentioned in "Vision and Voyages for Planetary Science in the Decade 2013-2022''. However, perhaps one of the most significant rationales for asteroid studies is the number of close approaches that have been documented recently. A space mission with a planetary defense objective aims to deflect the threatening body as far as possible from Earth. The design of a mission that optimally deflects an asteroid has different challenges: speed, precision, and system trade-off. This work addresses such issues and develops a fast transcription of the problem that can be implemented into an optimization tool, which allows for a broader trade study of different mission concepts with a medium fidelity. Such work is suitable for a mission?s preliminary study. It is shown, using the fictitious asteroid impact scenario 2017 PDC, that the complete tool is able to account for the orbit sensitivity to small perturbations and quickly optimize a deflection trajectory. The speed in which the tool operates allows for a trade study between the available hardware. As a result, key deflection dates and mission strategies are identified for the 2017 PDC

    The Multi-Spectral Solar Telescope Array (MSSTA)

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    In 1987, our consortium pioneered the application of normal incidence multilayer X-ray optics to solar physics by obtaining the first high resolution narrow band, "thermally differentiated" images of the corona', using the emissions of the Fe IX/Fe X complex at ((lambda)lambda) approx. 171 A to 175 A, and He II Lyman (beta) at 256 A. Subsequently, we developed a rocket borne solar observatory, the Multi Spectral Solar Telescope Array (MSSTA) that pioneered multi-thermal imaging of the solar atmosphere, using high resolution narrow band X-ray, EUV and FUV optical systems. Analysis of MSSTA observations has resulted in four significant insights into the structure of the solar atmosphere: (1) the diameter of coronal loops is essentially constant along their length; (2) models of the thermal and density structure of polar plumes based on MSSTA observations have been shown to be consistent with the thesis that they are the source of high speed solar wind streams; (3) the magnetic structure of the footpoints of polar plumes is monopolar, and their thermal structure is consistent with the thesis that the chromosphere at their footpoints is heated by conduction from above; (4) coronal bright points are small loops, typically 3,500 - 20,000 km long (5 sec - 30 sec); their footpoints are located at the poles of bipolar magnetic structures that are are distinguished from other network elements by having a brighter Lyman a signature. Loop models derived for 26 bright points are consistent with the thesis that the chromosphere at their footpoints is heated by conduction from the corona
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