A logistic regression model for microalbuminuria prediction in overweight male population

Background: Obesity promotes progression to microalbuminuria and increases the risk of chronic kidney disease. Current protocols of screening microalbuminuria are not recommended for the overweight or obese.

Design and Methods: A cross-sectional study was conducted. The relationship between metabolic risk factors and microalbuminuria was investigated. A regression model based on metabolic risk factors was developed and evaluated for predicting microalbuminuria in the overweight or obese.

Results: The prevalence of MA reached up to 17.6% in Chinese overweight men. Obesity, hypertension, hyperglycemia and hyperuricemia were the important risk factors for microalbuminuria in the overweight. The area under ROC curves of the regression model based on the risk factors was 0.82 in predicting microalbuminuria, meanwhile, a decision threshold of 0.2 was found for predicting microalbuminuria with a sensitivity of 67.4% and specificity of 79.0%, and a global predictive value of 75.7%. A decision threshold of 0.1 was chosen for screening microalbuminuria with a sensitivity of 90.0% and specificity of 56.5%, and a global predictive value of 61.7%.

Conclusions: The prediction model was an effective tool for screening microalbuminuria by using routine data among overweight populations

On the Role of Surface Friction in Tropical Intraseasonal Oscillation

The Madden-Julian oscillation (MJO), or the tropical intraseasonal oscillation, has attracted much attention, ever since its discovery in the early seventies for reasons of both scientific understanding and practical forecasts. Among the theoretical interpretations of the MJO, the wave-CISK (conditional instability of the second kind) mechanism is the most popular. The basic idea of the wave-CISK interpretation is that the cooperation between the low-level convergence associated with the eastward moving Kelvin wave and the cumulus convection generates an eastward moving Kelvin-wave-like mode. Later it was recognized that the MJO has an important Rossby-wave-like component. However linear analysis and numerical simulations based on it (even when conditional heating is used) have revealed two problems with the wave-CISK interpretation; i.e., excessive speed and the most preferred scale being zero or grid scale. Chao (1995) presented a discussion of these problems and attributed these problems to the particular type of expression for the cumulus heating used in the linear analyses and numerical studies (i.e., the convective heating is proportional to low-level convergence and a fixed vertical heating profile). It should be pointed out that in the relatively successful simulation of MJO with general circulation models the problem of grid scale being the most preferred scale does not appear and die problem of excessive speed is not as severe as in the linear analysis

The impacts of increased heat stress events on wheat yield under climate change in China

China is the largest wheat producing country in the world. Wheat is one of the two major staple cereals consumed in the country and about 60% of Chinese population eats the grain daily. To safeguard the production of this important crop, about 85% of wheat areas in the country are under irrigation or high rainfall conditions. However, wheat production in the future will be challenged by the increasing occurrence and magnitude of adverse and extreme weather events. In this paper, we present an analysis that combines outputs from a wide range of General Circulation Models (GCMs) with observational data to produce more detailed projections of local climate suitable for assessing the impact of increasing heat stress events on wheat yield. We run the assessment at 36 representative sites in China using the crop growth model CSM-CropSim Wheat of DSSAT 4.5. The simulations based on historical data show that this model is suitable for quantifying yield damages caused by heat stress. In comparison with the observations of baseline 1996-2005, our simulations for the future indicate that by 2100, the projected increases in heat stress would lead to an ensemble-mean yield reduction of –7.1% (with a probability of 80%) and –17.5% (with a probability of 96%) for winter wheat and spring wheat, respectively, under the irrigated condition. Although such losses can be fully compensated by CO2 fertilization effect as parameterized in DSSAT 4.5, a great caution is needed in interpreting this fertilization effect because existing crop dynamic models are unable to incorporate the effect of CO2 acclimation (the growth enhancing effect decreases over time) and other offsetting forces

Improving numerical simulation of typhoon LEKIMA(2019) through assimilating ATMS radiance data

&amp;lt;p&amp;gt;Lacking of high-resolution observations over oceans is one of the major problems for the numerical simulation of the tropical cyclones (TC), especially for the tropical cyclone inner-core structure&amp;amp;#8217;s simulation. Satellite observations plays an important role in improving the forecast skills of numerical weather prediction (NWP) systems. Many studies have suggested that the assimilation of satellite radiance data can substantially improve the numerical weather forecast skills for global model. However, the performance of satellite radiance data assimilation in limited-area modeling systems is still controversial.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;This study attempts to investigate the impact of assimilation of the Advanced Technology Microwave Sounder (ATMS) satellite radiances data and its role to improve the model initial condition and forecast of typhoon LEKIMA(2019) using a regional mesoscale model. In this study, detailed analysis of the data impact will be presented, also the results from different data assimilation methods and different data usage schemes will be discussed.&amp;lt;/p&amp;gt; </jats:p

Intraseasonal Oscillations over South America: A Study with a Regional Climate Model

The National Center for Atmospheric Research (NCAR) regional climate model version 2 (RegCM2) is used to investigate the observed characteristics of intraseasonal oscillations over South America. Our study is mainly concentrated on an intraseaonal mode, which is observed to account for a large portion of the intraseasonal variation, to have a standing feature and to be independent of the MJO. The NCEPDOE AMIP-II reanalysis is utilized to provide initial and lateral boundary conditions for the RegCM2 based upon the OOZ, 062, 122 and 182 data.Our results indicate that the intraseasonal oscillation still exists with time- averaged lateral boundary condition, which prevents the MJO and other outside disturbances from entering the model's domain, suggesting a locally forced oscillation responsible for ths intraseasonal mode independent of the MJO. Further experiments show that the annual and daily variabilities and a radiative-convective interaction are not essential to the locally forced intraseasonal oscillation. The intraseasonal oscillations over Amazon in our model essentially result from interactions among atmospheric continental- scale circulation, surface radiation, surface sensible and latent heat fluxes, and cumulus convection. The wavelet analyses of various surface energy fluxes and surface energy budget also verify that the primary cause of intraseasonal oscillation is the interaction of land surface processes with the atmosphere