13,573 research outputs found
Fever of Unknown Origin: An Unusual Case
Recurrent episodic fever of unknown origin (FUO) arising from tumour of the gastrointestinal tract is rare. We report an otherwise healthy 62-year-old man with recurrent circumscribed bouts of fever and raised CRP for 3 years who has remained well and fever-free 2 years after the removal of a well-differentiated adenocarcinoma of the colon. Occult colonic neoplasm should be considered and sought when routine investigations for FUO are negative
Insular Carcinoma of Thyroid Presenting as a Giant Skull Lesion: A Dilemma in Treatment.
Thyroid surgeons are becoming increasingly more aware of a histologically distinct subset of thyroid carcinoma whose classification falls between well-differentiated and anaplastic carcinomas with respect to both cell differentiation and clinical behavior. This subtype of tumors has been categorized as poorly differentiated or insular carcinoma, based on its characteristic cell groupings. Although the differentiation of insular carcinoma from other thyroid carcinomas has important prognostic and therapeutic significance, relatively little about insular carcinoma has been published in the otolaryngology literature. In this article, we discuss a case of insular carcinoma of thyroid presenting with concurrent distant metastasis to skull, lung, ribs, and inguinal region with review of the literature. We conclude that insular thyroid carcinoma warrants aggressive management with total thyroidectomy and excision of accessible giant lesion followed by radioactive iodine ablation of any remaining thyroid tissue
Pion-less effective field theory for atomic nuclei and lattice nuclei
We compute the medium-mass nuclei O and Ca using pionless
effective field theory (EFT) at next-to-leading order (NLO). The low-energy
coefficients of the EFT Hamiltonian are adjusted to experimantal data for
nuclei with mass numbers and , or alternatively to results from
lattice quantum chromodynamics (QCD) at an unphysical pion mass of 806 MeV. The
EFT is implemented through a discrete variable representation in the harmonic
oscillator basis. This approach ensures rapid convergence with respect to the
size of the model space and facilitates the computation of medium-mass nuclei.
At NLO the nuclei O and Ca are bound with respect to decay into
alpha particles. Binding energies per nucleon are 9-10 MeV and 30-40 MeV at
pion masses of 140 MeV and 806 MeV, respectively.Comment: 26 page
A New Simulation Metric to Determine Safe Environments and Controllers for Systems with Unknown Dynamics
We consider the problem of extracting safe environments and controllers for
reach-avoid objectives for systems with known state and control spaces, but
unknown dynamics. In a given environment, a common approach is to synthesize a
controller from an abstraction or a model of the system (potentially learned
from data). However, in many situations, the relationship between the dynamics
of the model and the \textit{actual system} is not known; and hence it is
difficult to provide safety guarantees for the system. In such cases, the
Standard Simulation Metric (SSM), defined as the worst-case norm distance
between the model and the system output trajectories, can be used to modify a
reach-avoid specification for the system into a more stringent specification
for the abstraction. Nevertheless, the obtained distance, and hence the
modified specification, can be quite conservative. This limits the set of
environments for which a safe controller can be obtained. We propose SPEC, a
specification-centric simulation metric, which overcomes these limitations by
computing the distance using only the trajectories that violate the
specification for the system. We show that modifying a reach-avoid
specification with SPEC allows us to synthesize a safe controller for a larger
set of environments compared to SSM. We also propose a probabilistic method to
compute SPEC for a general class of systems. Case studies using simulators for
quadrotors and autonomous cars illustrate the advantages of the proposed metric
for determining safe environment sets and controllers.Comment: 22nd ACM International Conference on Hybrid Systems: Computation and
Control (2019
Trends and Establishment of Shell Effects in (n, d), (n, t) and (n, 3He) Reaction Cross Sections Around 14 MeV
Unexpected sneezing after a peribulbar injection in a patient for elective cataract surgery
Sneezing or the sternutatory reflex, inborn in most animals, is a primitive neuromuscular physiological response to irritation. Sometimes, unusual sneezing occurs during and immediately after a peribulbar block, which is generally performed with a local anaesthetic in awake patients. We present a case report of an awake elderly male who experienced unexpected continuous sneezing immediately after the removal of the needle used for the peribulbar block, which was subsequently relieved with pheniramine maleate.Keywords: peribulbar block, pheniramine maleate, sneezin
Reversible inhibition of oligodendrocyte progenitor differentiation by a monoclonal antibody against surface galactolipids.
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