14,183 research outputs found
Association of Intraocular Pressure With Human Immunodeficiency Virus
PURPOSE: Prior studies have shown an association between human immunodeficiency virus (HIV) and reduced intraocular pressures (IOP). The purpose of this study was to determine if patients with HIV on highly active antiretroviral therapy (HAART) had any difference in their IOP compared with patients without HIV or with HIV who are not on HAART. DESIGN: Retrospective cross-sectional study. METHODS: We included 400 patients from our academic eye center between 2000 and 2016. Group 1 (G1) consisted of patients with HIV on HAART (n = 176), Group 2 (G2) consisted of patients with HIV who were not on HAART (n = 48), and Group 3 (G3) consisted of controls without HIV (n = 176). An analysis of variance (ANOVA) was performed to compare mean IOP values. Multivariate linear and logistic regression models were performed to assess factors impacting IOP. Difference in IOP was the primary outcome being measured. RESULTS: The mean IOPs in mm Hg were 13.7 +/- 5.1 (G1), 13.1 +/- 3.6 (G2), and 17.3 +/- 3.8 (G3), P \u3c .01. In regression modeling, having a CD4 count CONCLUSIONS: Absolute CD4 counts may play a role in IOP fluctuations. This association was found in patients with HIV regardless of whether patients were on HAART
Accuracy and Precision of Occlusal Contacts of Stereolithographic Casts Mounted by Digital Interocclusal Registrations
Statement of problem Little peer-reviewed information is available regarding the accuracy and precision of the occlusal contact reproduction of digitally mounted stereolithographic casts. Purpose The purpose of this in vitro study was to evaluate the accuracy and precision of occlusal contacts among stereolithographic casts mounted by digital occlusal registrations. Material and methods Four complete anatomic dentoforms were arbitrarily mounted on a semi-adjustable articulator in maximal intercuspal position and served as the 4 different simulated patients (SP). A total of 60 digital impressions and digital interocclusal registrations were made with a digital intraoral scanner to fabricate 15 sets of mounted stereolithographic (SLA) definitive casts for each dentoform. After receiving a total of 60 SLA casts, polyvinyl siloxane (PVS) interocclusal records were made for each set. The occlusal contacts for each set of SLA casts were measured by recording the amount of light transmitted through the interocclusal records. To evaluate the accuracy between the SP and their respective SLA casts, the areas of actual contact (AC) and near contact (NC) were calculated. For precision analysis, the coefficient of variation (CoV) was used. The data was analyzed with t tests for accuracy and the McKay and Vangel test for precision (α=.05). Results
The accuracy analysis showed a statistically significant difference between the SP and the SLA cast of each dentoform (PPP Conclusions For the accuracy evaluation, statistically significant differences were found between the occlusal contacts of all digitally mounted SLA casts groups, with an increase in AC values and a decrease in NC values. For the precision assessment, the CoV values of the AC and NC showed the digitally articulated cast’s inability to reproduce the uniform occlusal contacts
Large-scale exact diagonalizations reveal low-momentum scales of nuclei
Ab initio methods aim to solve the nuclear many-body problem with controlled
approximations. Virtually exact numerical solutions for realistic interactions
can only be obtained for certain special cases such as few-nucleon systems.
Here we extend the reach of exact diagonalization methods to handle model
spaces with dimension exceeding on a single compute node. This allows
us to perform no-core shell model (NCSM) calculations for 6Li in model spaces
up to and to reveal the 4He+d halo structure of this
nucleus. Still, the use of a finite harmonic-oscillator basis implies
truncations in both infrared (IR) and ultraviolet (UV) length scales. These
truncations impose finite-size corrections on observables computed in this
basis. We perform IR extrapolations of energies and radii computed in the NCSM
and with the coupled-cluster method at several fixed UV cutoffs. It is shown
that this strategy enables information gain also from data that is not fully UV
converged. IR extrapolations improve the accuracy of relevant bound-state
observables for a range of UV cutoffs, thus making them profitable tools. We
relate the momentum scale that governs the exponential IR convergence to the
threshold energy for the first open decay channel. Using large-scale NCSM
calculations we numerically verify this small-momentum scale of finite nuclei.Comment: Minor revisions.Accepted for publication in Physical Review
Pion-less effective field theory for atomic nuclei and lattice nuclei
We compute the medium-mass nuclei O and Ca using pionless
effective field theory (EFT) at next-to-leading order (NLO). The low-energy
coefficients of the EFT Hamiltonian are adjusted to experimantal data for
nuclei with mass numbers and , or alternatively to results from
lattice quantum chromodynamics (QCD) at an unphysical pion mass of 806 MeV. The
EFT is implemented through a discrete variable representation in the harmonic
oscillator basis. This approach ensures rapid convergence with respect to the
size of the model space and facilitates the computation of medium-mass nuclei.
At NLO the nuclei O and Ca are bound with respect to decay into
alpha particles. Binding energies per nucleon are 9-10 MeV and 30-40 MeV at
pion masses of 140 MeV and 806 MeV, respectively.Comment: 26 page
Unexpected sneezing after a peribulbar injection in a patient for elective cataract surgery
Sneezing or the sternutatory reflex, inborn in most animals, is a primitive neuromuscular physiological response to irritation. Sometimes, unusual sneezing occurs during and immediately after a peribulbar block, which is generally performed with a local anaesthetic in awake patients. We present a case report of an awake elderly male who experienced unexpected continuous sneezing immediately after the removal of the needle used for the peribulbar block, which was subsequently relieved with pheniramine maleate.Keywords: peribulbar block, pheniramine maleate, sneezin
Dataplane Specialization for High-performance OpenFlow Software Switching
OpenFlow is an amazingly expressive dataplane program-
ming language, but this expressiveness comes at a severe
performance price as switches must do excessive packet clas-
sification in the fast path. The prevalent OpenFlow software
switch architecture is therefore built on flow caching, but
this imposes intricate limitations on the workloads that can
be supported efficiently and may even open the door to mali-
cious cache overflow attacks. In this paper we argue that in-
stead of enforcing the same universal flow cache semantics
to all OpenFlow applications and optimize for the common
case, a switch should rather automatically specialize its dat-
aplane piecemeal with respect to the configured workload.
We introduce ES WITCH , a novel switch architecture that
uses on-the-fly template-based code generation to compile
any OpenFlow pipeline into efficient machine code, which
can then be readily used as fast path. We present a proof-
of-concept prototype and we demonstrate on illustrative use
cases that ES WITCH yields a simpler architecture, superior
packet processing speed, improved latency and CPU scala-
bility, and predictable performance. Our prototype can eas-
ily scale beyond 100 Gbps on a single Intel blade even with
complex OpenFlow pipelines
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