Contentious Consultations: Black Communities, Corporate Experts, and the Constitutional Court in Colombia’s Coal Region

Across the Global South, corporations and governments are displacing Indigenous and Afro-descendant groups in the name of development and economic advancement. International norms guarantee these communities the right to consultation over extractive projects that impact their traditional territories. Ethnic rights laws create spaces for communities to hold corporations accountable for their suffering; the same laws can also allow corporations to co-opt the process. Using a case study from Colombia, I argue that two Black communities filed a petition to seek reparations for a wide range of harms caused by mining yet found themselves on trial over whether they were really a community at all. Corporate officials positioned themselves as the experts on community identity and history and used the communities’ lack of collectivity to discredit the communities’ ethnic rights claims. This article brings together anthropological literature on the social life of corporations and scholarly critiques of ethnic rights laws to illustrate that when communities engage ethnic rights laws, they also undergo new processes of community formation in their interactions with corporations, courts, and international institutions

Military Veteran-offenders: Making sense of developments in the debate to inform service delivery

In a 2008 report by the National Association for Probation Officers it was estimated that in excess of 20,000 ex-service personnel were serving a sentence in either prison or the community. Since this report, we have witnessed a steady growth in research, literature and knowledge exchange seeking to make sense of veterans' offending. This paper provides a brief overview of the key development of this debate since the recognition of the 'problem' of ex-military personnel in prison. Our discussion problematizes focussing solely on offending by suggesting that the quality of transition is in fact contingent on a more complex interplay of social, cultural and economic participation-linked factors. We propose that by considering the complexities of transition, veterans' offending is more appropriately positioned amongst wider structural challenges faced on return to civilian society. This approach informs the limited recent empirical work in this area, which has been slow to filter into mainstream criminal justice practice. It is our contention that veterans' contact with the criminal justice system needs to be understood within the broader explanatory frameworks of diversity and social inclusion. This paper makes specific recommendations, based on new developments in the veteran-offender debate, to inform service delivery to this cohort in the criminal justice system

A comparative study of the perceptions of professional staff on their contribution to student outcomes

This is an Accepted Manuscript of an article published by Taylor & Francis Group in Journal of Higher Education Policy and Management on 14/8/2014, available online: http://www.tandfonline.com/10.1080/1360080X.2014.936093This journal articles examines the perceptions of professional staff on their contribution to student outcomes

Carbon-13 in groundwater from English and Norwegian crystalline rock aquifers: a tool for deducing the origin of alkalinity?

The 13C signature is evaluated for various environmental compartments (vegetation, soils, soil gas, rock and groundwater) for three crystalline rock terrains in England and Norway. The data are used to evaluate the extent to which stable carbon isotopic data can be applied to deduce whether the alkalinity in crystalline bedrock groundwaters has its origin in hydrolysis of carbonate or silicate minerals by CO2. The resolution of this issue has profound implications for the role of weathering of crystalline rocks as a global sink for CO2. In the investigated English terrain (Isles of Scilly), groundwaters are hydrochemically immature and DIC is predominantly in the form of carbonic acid with a soil gas signature. In the Norwegian terrains, the evidence is not conclusive but is consistent with a significant fraction of the groundwater DIC being derived from silicate hydrolysis by CO2. A combined consideration of pH, alkalinity and carbon isotope data, plotted alongside theoretical evolutionary pathways on bivariate diagrams, strongly suggests real evolutionary pathways are likely to be hybrid, potentially involving both open and closed CO2 conditions

A model for predicting dissolved organic carbon distribution in a reservoir water using fluorescence spectroscopy

A number of water treatment works (WTW) in the north of England (UK) have experienced problems in reducing the dissolved organic carbon (DOC) present in the water to a sufficiently low level. The problems are experienced in autumn/ winter when the colour increases and the coagulant dose at the WTW needs to be increased in order to achieve sufficient colour removal. However, the DOC content of the water varies little throughout the year. To investigate this further, the water was fractionated using resin adsorption techniques into its hydrophobic (fulvic and humic acid fractions) and hydrophilic (acid and non-acid fractions) components. The fractionation process yields useful information on the changing concentration of each fraction but is time consuming and labour intensive. Here, a method of rapidly determining fraction concentration was developed using fluorescence spectroscopy. The model created used synchronous spectra of fractionated material compared against bulk water spectra and predicted the fraction concentrations to within 10% for a specific water. The model was unable to predict fraction concentrations for waters from a different watershed

Molecular investigation of Bdellovibrio bacteriovorus envelope processes associated with bacterial predation

Antibiotics have been used to treat bacterial infections for nearly 80 years, however, the increasing emergence of antibiotic-resistant bacteria has now led to a significant global burden of antimicrobial resistance (AMR) and a worldwide healthcare crisis. Combatting AMR requires the complementary development of novel therapeutics. Bdellovibrio bacteriovorus is a small predatory bacterium that invades Gram-negative prey, replicates within the periplasm and then lyses the host cell. This predatory ability presents B. bacteriovorus as a potential novel antimicrobial therapeutic. In this thesis, I describe two short research projects which investigate the predatory envelope processes of gliding motility and cell wall-modification in B. bacteriovorus. B. bacteriovorus uses gliding motility on surfaces to both scout for prey and to ultimately facilitate exit from the dead host. Cyclic-di-GMP (c-di-GMP) positively regulates gliding motility in B. bacteriovorus and c-di-GMP signals are transduced through PilZ domains of receptor proteins. Some B. bacteriovorus PilZ proteins contain an additional putative GYF domain. We hypothesised that PilZ: GYF hybrid proteins may bind c-di-GMP (via the PilZ domain) and interact with the gliding motor (via the GYF domain) to regulate gliding motility. We aimed to test this hypothesis by crystallising the PilZ: GYF protein Bd1996. Bd1996 homologues from two different B. bacteriovorus strains were successfully expressed and purified. Bd1996 bound c-di-GMP in vitro, however, neither protein homologue could be crystallised. Modification of predator and prey cell walls is an important predatory process that involves a repertoire of different enzymes. In my second project, I investigated the function of the two cell wall-modifying enzymes Bd1402 and Bd1075. Bd1402 was secreted into the periplasm of the prey in which it may modify the prey cell wall. In contrast, Bd1075 localised to the B. bacteriovorus predator itself and an unmarked deletion of bd1075 resulted in the formation of predator cells that were straight rods, in comparison to vibroid wild-type cells. Together, these data suggest that Bd1075 is the curvature-determinant of B. bacteriovorus HD100

Catchment-scale assessments of the effects of abandoned metal mines on groundwater quality and stream ecology

This paper presents an overview of a British Geological Survey catchment-scale research project designed to quantify catchment-derived metal loading on surface water quality. This work is focused on the Rookhope Burn, a tributary of the River Wear in the North Pennines, UK. The river has been identified in the Water Framework Directive (WFD) River Basin Management report as being at risk of failing to achieve Good Status due to mines and minewater pressures. Although geologically relatively simple, the catchment is hydrogeologically complex in that it comprises an area of entrenched karst, characterised by Lower Carboniferous Limestone exposed in the base of valleys overlain by Namurian strata, comprising interbedded shales, sandstones and limestones, which are capped by drained blanket peat. Metal loadings in this catchment result from lead and zinc mineralization and its historic exploitation and processing, which have resulted in both point source and diffuse impacts within the catchment. There have been three main phases of research: (i) collection of hydrological and water chemistry data to enable loading and mass balance calculations to be undertaken; (ii) development of a conceptual understanding of the hydrology and hydrogeology of the catchment, and (iii) application of the hydrological understanding to more recent baseline monitoring of ecological impacts. This work has identified previously unreported mine and groundwater contributions to the catchment, which may have significant implications for the design of remedial measures in the catchment

Pre-hybridisation: an efficient way of suppressing endogenous biotin-binding activity inherent to biotin–streptavidin detection system

Endogenous biotin or biotinylated protein binding activity is a major drawback to biotin-avidin/streptavidin detection system. The avidin/streptavidin conjugate used to detect the complex of the biotinylated secondary antibody and the primary antibody binds to endogenous biotin or biotinylated proteins leading to non-specific signals. In Western blot, the endogenous biotin or biotinylated protein binding activity is usually manifested in the form of ~72kDa, ~75kDa and ~150kDa protein bands, which often mask the signals of interest. To overcome this problem, a method based on prior hybridisation of the biotinylated secondary antibody and the streptavidin conjugate was developed. The method was tested alongside the conventional biotin-streptavidin method on proteins extracted from zebrafish (Danio rerio) embryos. Results showed that the newly developed method efficiently suppresses the endogenous biotin or biotinylated protein binding activity inherent to the biotin-streptavidin detection system

Eye Gaze and Perceptual Adaptation to Audiovisual Degraded Speech

Purpose Visual cues from a speaker's face may benefit perceptual adaptation to degraded speech, but current evidence is limited. We aimed to replicate results from previous studies to establish the extent to which visual speech cues can lead to greater adaptation over time, extending existing results to a real-time adaptation paradigm (i.e., without a separate training period). A second aim was to investigate whether eye gaze patterns toward the speaker's mouth were related to better perception, hypothesizing that listeners who looked more at the speaker's mouth would show greater adaptation. Method A group of listeners (n = 30) was presented with 90 noise-vocoded sentences in audiovisual format, whereas a control group (n = 29) was presented with the audio signal only. Recognition accuracy was measured throughout and eye tracking was used to measure fixations toward the speaker's eyes and mouth in the audiovisual group. Results Previous studies were partially replicated: The audiovisual group had better recognition throughout and adapted slightly more rapidly, but both groups showed an equal amount of improvement overall. Longer fixations on the speaker's mouth in the audiovisual group were related to better overall accuracy. An exploratory analysis further demonstrated that the duration of fixations to the speaker's mouth decreased over time. Conclusions The results suggest that visual cues may not benefit adaptation to degraded speech as much as previously thought. Longer fixations on a speaker's mouth may play a role in successfully decoding visual speech cues; however, this will need to be confirmed in future research to fully understand how patterns of eye gaze are related to audiovisual speech recognition. All materials, data, and code are available at https://osf.io/2wqkf/

GP and parent dissonance about the assessment and treatment of childhood eczema in primary care:a qualitative study

ObjectivesTo compare parents’ and clinicians’ perspectives on the assessment and treatment of children with eczema in primary care.DesignQualitative interview study with purposive and snowball sampling and thematic analysis.Setting14 general practices in the UK.Participants11 parents of children with eczema and 15 general practitioners (GPs) took part in semistructured individual interviews.ResultsWe identified several areas of dissonance between parents and GPs. First, parents sought a ‘cause’ of eczema, such as an underlying allergy, whereas GPs looked to manage the symptoms of an incurable condition. Second, parents often judged eczema severity in terms of psychosocial impact, while GPs tended to focus on the appearance of the child’s skin. Third, parents sought ‘more natural’ over-the-counter treatments or complementary medicine, which GPs felt unable to endorse because of their unknown effectiveness and potential harm. Fourth, GPs linked poor outcomes to unrealistic expectations of treatment and low adherence to topical therapy, whereas parents reported persisting with treatment and despondency with its ineffectiveness. Consultations were commonly described by parents as being dominated by the GP, with a lack of involvement in treatment decisions. GPs’ management of divergent views varied, but avoidance strategies were often employed.ConclusionsDivergent views between parents and clinicians regarding the cause and treatment of childhood eczema can probably only be bridged by clinicians actively seeking out opinions and sharing rationale for their approach to treatment. Together with assessing the psychosocial as well as the physical impact of eczema, asking about current or intended use of complementary therapy and involving parents in treatment decisions, the management of eczema and patient outcomes could be improved.</jats:sec