Phytochemistry investigation and antioxidant activity of four edible Verbenaceae of Burkina Faso

Lantana rhodesiensis Moldenke, Lippia chevalieri Moldenke, Vitex diversifolia Bak and Vitex doniana Sweet are four species of Verbenaceae family widely used in traditional medicines in Burkina. The aim of this investigation was to study the chromatographic profile of phenols acids and that of the flavonoids as well as the antioxidants activities. Then, three types of extraction were made: acetonic (100%), decoction, ethanol-water(80/20 + 20/80); and fractions of ethanol-water which arehexane fraction (HF), ethyl acetate fraction (EAF), butanol fraction (BF) and aqueous fraction (AqF) of each species. These evaluations were supplemented by the quantification of the metal ions and the characterization by atomic absorption and HPLC-DAD methods of totals phenols acids and totals flavonoids.The whole of these proportioning was directed against the antioxidant activity through the anti-DPPH* (free radical scavenging activity), anti-TAC (total antioxidant capacity) and anti-IRP(iron reducing power).36 flavonoids on 41 were highlighted by the HPLC-DAD method. A derivative glycosylate of quercetin was detected in the V. diversifolia extracts. L. chevalieri presented the strongest value in terms of ions content with a 55.88 g/kg of calcium.In terms of antioxidant activity, L. rhodesiensis and L. chevalieri presented the best activities on total antioxidant activity and anti-DPPH, and iron reducing power respectively.It’s arise that decoction extract have the best’s activities and can justify the traditional uses

Polyphenolic composition of Lantana camara and Lippia chevalieri, and their Antioxidant and Antimicrobial Activities

In the present study, the antioxidant and antibacterial activities of methanolic extracts of two Verbenaceae (Lantana camara L. and Lippia chevalieri Moldenke: aerial part) were investigated. Their polyphenolic composition in the ethyl acetate and aqueous fractions were characterized by HPLC-DAD. The antioxidant capability of the methanolic extracts was assessed by the Ferric Reducing Antioxidant Power (FRAP) and the scavenging activity of the free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH). The Minimum Inhibitory Concentrations (MIC) of the methanolic extracts (25 µg mL-1), and the minimum bactericidal concentrations (MBC) (12.5 µg mL-1) against 13 pathogenic bacteria and four serotyped bacteria from the American Type Culture Collection (ATCC) were also determined by the agar-well diffusion method. The results indicated that the L. chevalieri extracts are rich in phenolic compounds (among the 27 polyphenolic compounds detected, 20 belong to L. chevalieri) and showed the highest antioxidant activities, simultaneously on iron (III) to iron (II)-reducing activity and the radical scavenging activity. However, L. camara displayed the best and the broadest antimicrobial spectrum, especially on Shigella flexneri and Pantoea sp. (two Gram-negative strains of bacteria). The nature of polyphenolics compounds detected (phenol acid and flavone) in the L. camara can justify this activity.Key words: Verbenaceae, HPLC-DAD, antioxidant activity, antimicrobial activity, polyphenolic compound

Medicinal Plants used in the Treatment of Hepatitis in BoboDioulasso: Studying the Availability and Analyzing the Phytochemical Properties of Combretum micranthum G. Don and Entada africana Guill. et Perr.

This paper focuses on studying the inventory of the medicinal plants used in hepatitis care in Bobo-Dioulasso and evaluating their availability in local vegetation and their phytochemical properties. To achieve this objective, several approaches were developed which include: (1) an ethnobotanical survey among 111 traditional health practitioners (THP); (2) a dendrometric study to evaluate the abundance and spatial distribution of these species in Dindérésso Classified Forest; and (3) an evaluation of polyphenolic compounds and antioxidant activity of the two most quoted species roots using three methods such as anti-DPPH*, anti-FRAP, and antiABTS. The results show that Entada africana and Combretum micranthum were the most quoted species among 40 species used in the treatment of liver disease. The availability study revealed that juvenile and adult individuals of E. africana are frequent in woody savannah, shrubby savannah, and grassy savannah. As for juvenile and adult C. micranthum individuals, they are only frequent in wooded savannah (RI<60%). These populations are therefore declining due to anthropogenic pressure. Phytochemical analysis reveal polyphenols contents of 37.91 and 20.71 mg EAG/100 mg respectively for C. micranthum and E. africana and flavonoids contents of 0.85 ± 0.09 and 0.66 ± 0.05 mg EQ/100 mg respectively for C. micranthum and E. africana. Finally, the results show that there is an anti-oxidant activity for the two species. There were about 198 and 13 μmol EAA/g for the two species i.e., ABTS and DPPH, respectively. The results show that the antioxidant activity could partially justify the traditional use of this plant

Phytochemistry investigation and antioxidant activity of four edible Verbenaceae of Burkina Faso

info:eu-repo/semantics/publishe

A review on Lantana rhodesiensis Moldenke: traditional uses, phytochemical constituents and pharmacological activities

Lantana rhodesiensis Moldenke an herbaceous, belonging to the Verbenaceae family is widely used in Africa folk medicine for the treatment of cancer, measles, malaria, smallpox, strength, coughs, fever, rheumatism, body pains, diabetes mellitus arrhythmia, parasitic diseases, arterial hypertension, old diarrhoeas. Many studies have been conducted on the chemical composition of the whole plant of L. rhodesiensis as well as biological activities.  The aim of the present review was to give a detailed literature survey on its traditional uses, phytochemistry and therapeutical properties of L. rhodesiensis

Febs Letters

Lippia chevalieri Moldenke is an herbaceous, belonging to the Verbenaceae family largely used in folk medicine in Burkina Faso and in certain African countries. The aim of the present review was to give a detailed literature survey on its traditional uses, and phytochemistry and therapeutical properties in order to systematize achievements and direct further research. Composition and biological activities of its essential oil have been largely investigated. Literature shows that this species of plant is used mostly for the treatment of malaria, mental disorder, liver pathologies, hepatitis, anemia and respiratory disorders. We note that the most published studies on this plant are concerned to its content of essential oil