Development of Primary Care, Lifestyle Disease and New Elderly Association (NEA) in Japan : Common Philosophy With Hinohara-ism

Dr. Shigeaki Hinohara, one of the most eminent physician in Japan lived up to 105, was chairman emeritus of St. Luke’s International University and honorary president of St. Luke’s International Hospital. He was a pioneer in several fields with remarkable contribution. He introduced and developed primary care (PC) medicine in Japan. The term “life style-related disease” was proposed by him, and decided to use widely by the Ministry of Health and Welfare, Japan. He started New Elderly Association (NEA) to make aged people significant life physically and psychologically with wide spread. He firstly founded Japan BioMusic Association/Japanese Music Therapy Association (JMTA) and developed music therapy in Japan. Thus, by his excellent leadership and management, medical and cultural fields have developed to high degree in Japan

The ASTRO-H X-ray Observatory

The joint JAXA/NASA ASTRO-H mission is the sixth in a series of highly successful X-ray missions initiated by the Institute of Space and Astronautical Science (ISAS). ASTRO-H will investigate the physics of the high-energy universe via a suite of four instruments, covering a very wide energy range, from 0.3 keV to 600 keV. These instruments include a high-resolution, high-throughput spectrometer sensitive over 0.3-2 keV with high spectral resolution of Delta E < 7 eV, enabled by a micro-calorimeter array located in the focal plane of thin-foil X-ray optics; hard X-ray imaging spectrometers covering 5-80 keV, located in the focal plane of multilayer-coated, focusing hard X-ray mirrors; a wide-field imaging spectrometer sensitive over 0.4-12 keV, with an X-ray CCD camera in the focal plane of a soft X-ray telescope; and a non-focusing Compton-camera type soft gamma-ray detector, sensitive in the 40-600 keV band. The simultaneous broad bandpass, coupled with high spectral resolution, will enable the pursuit of a wide variety of important science themes.Comment: 22 pages, 17 figures, Proceedings of the SPIE Astronomical Instrumentation "Space Telescopes and Instrumentation 2012: Ultraviolet to Gamma Ray

Hitomi (ASTRO-H) X-ray Astronomy Satellite

The Hitomi (ASTRO-H) mission is the sixth Japanese x-ray astronomy satellite developed by a large international collaboration, including Japan, USA, Canada, and Europe. The mission aimed to provide the highest energy resolution ever achieved at E  >  2  keV, using a microcalorimeter instrument, and to cover a wide energy range spanning four decades in energy from soft x-rays to gamma rays. After a successful launch on February 17, 2016, the spacecraft lost its function on March 26, 2016, but the commissioning phase for about a month provided valuable information on the onboard instruments and the spacecraft system, including astrophysical results obtained from first light observations. The paper describes the Hitomi (ASTRO-H) mission, its capabilities, the initial operation, and the instruments/spacecraft performances confirmed during the commissioning operations for about a month

Dispersible shortened boron nitride nanotubes with improved molecule-loading capacity

The oxidation process of boron nitride nanotubes was thoroughly investigated, and a slow oxidation characteristic was clearly revealed. Subsequently, the controllable oxidation process was utilized to break the sturdy structure of the boron nitride nanotubes to fabricate shortened nanotubes. The shortened boron nitride nanotubes were found to possess good solubility in water and many organic solvents. Further experiments demonstrated remarkably improved molecule-loading capacity of the shortened boron nitride nanotubes. These dispersible shortened boron nitride nanotubes might have the potential to be developed as effective delivery systems for various molecules, which may find applications in bio-related fields

Development of Primary Care, Lifestyle Disease and New Elderly Association (NEA) in Japan : Common Philosophy With Hinohara-ism

Dr. Shigeaki Hinohara, one of the most eminent physician in Japan lived up to 105, was chairman emeritus of St. Luke’s International University and honorary president of St. Luke’s International Hospital. He was a pioneer in several fields with remarkable contribution. He introduced and developed primary care (PC) medicine in Japan. The term “life style-related disease” was proposed by him, and decided to use widely by the Ministry of Health and Welfare, Japan. He started New Elderly Association (NEA) to make aged people significant life physically and psychologically with wide spread. He firstly founded Japan BioMusic Association/Japanese Music Therapy Association (JMTA) and developed music therapy in Japan. Thus, by his excellent leadership and management, medical and cultural fields have developed to high degree in Japan

Boron nitride nanotubes functionalized with mesoporous silica for intracellular delivery of chemotherapy drugs

Boron nitride nanotube (BNNT)@mesoporous silica hybrids with controllable surface zeta potential were fabricated for intracellular delivery of doxorubicin. The materials showed higher suspension ability, doxorubicin intracellular endocytosis efficiency, and LNcap prostate cancer cell killing ability compared with naked BNNTs

Multimodal luminescent-magnetic boron nitride nanotubes@NaGdF4:Eu structures for cancer therapy

Boron nitride nanotubes@NaGdF4:Eu composites with core@shell structures were fabricated giving the opportunity to trace, target and thus to manipulate BNNTs in vitro. The composites show a significantly higher cellular uptake and chemotherapy drug intracellular delivery ability in the presence of an external magnetic field than that in its absence