Interplay between Physics and Geometry in Balmer filaments: the Case of SN 1006

The analysis of Balmer-dominated emission in supernova remnants is potentially a very powerful way to derive information on the shock structure, on the physical conditions of the ambient medium and on the cosmic-ray acceleration efficiency. However, the outcome of models developed in plane-parallel geometry is usually not easily comparable with the data, since they often come from regions with rather a complex geometry. We present here a general scheme to disentangle physical and geometrical effects in the data interpretation, which is especially powerful when the transition zone of the shock is spatially resolved and the spectral resolution is high enough to allow a detailed investigation of spatial changes of the line profile. We then apply this technique to re-analyze very high quality data of a region along the northwestern limb of the remnant of SN~1006. We show how some observed features, previously interpreted only in terms of spatial variations of physical quantities, naturally arise from geometrical effects. With these effects under control, we derive new constraints on physical quantities in the analyzed region, like the ambient density (in the range 0.03-$0.1{\,\rm cm^{-3}}$), the upstream neutral fraction (more likely in the range 0.01-0.1), the level of face-on surface brightness variations (with factors up to $\sim 3$) and the typical scale lengths related to such variations ($\ge 0.1{\,\rm pc}$, corresponding to angular scales $\ge 10{\,\rm arcsec}$).Comment: 22 pages, 24 figures, 3 tables, accepted on 2018 November 21 for publication on MNRA

A novel ultrafast-low-dose computed tomography protocol allows concomitant coronary artery evaluation and lung cancer screening

BACKGROUND:Cardiac computed tomography (CT) is often performed in patients who are at high risk for lung cancer in whom screening is currently recommended. We tested diagnostic ability and radiation exposure of a novel ultra-low-dose CT protocol that allows concomitant coronary artery evaluation and lung screening. METHODS: We studied 30 current or former heavy smoker subjects with suspected or known coronary artery disease who underwent CT assessment of both coronary arteries and thoracic area (Revolution CT, General Electric). A new ultrafast-low-dose single protocol was used for ECG-gated helical acquisition of the heart and the whole chest. A single IV iodine bolus (70-90 ml) was used. All patients with CT evidence of coronary stenosis underwent also invasive coronary angiography. RESULTS: All the coronary segments were assessable in 28/30 (93%) patients. Only 8 coronary segments were not assessable in 2 patients due to motion artefacts (assessability: 98%; 477/485 segments). In the assessable segments, 20/21 significant stenoses (> 70% reduction of vessel diameter) were correctly diagnosed. Pulmonary nodules were detected in 5 patients, thus requiring to schedule follow-up surveillance CT thorax. Effective dose was 1.3 ± 0.9 mSv (range: 0.8-3.2 mSv). Noteworthy, no contrast or radiation dose increment was required with the new protocol as compared to conventional coronary CT protocol. CONCLUSIONS:The novel ultrafast-low-dose CT protocol allows lung cancer screening at time of coronary artery evaluation. The new approach might enhance the cost-effectiveness of coronary CT in heavy smokers with suspected or known coronary artery disease

Latino and Black smokers in the Health and Retirement Study are more likely to quit: the role of light smoking

Abstract Background Older persons are more vulnerable to tobacco mortality and less likely to make quit attempts. Less is known, however, about the role of race and ethnicity on quit rates in the U.S. Using a nationally representative data source of older adults in U.S., we aimed to study racial and ethnic differences in smoking cessation rates. Methods We used data from all waves of the Health and Retirement Study (HRS) between 1992-2012. The HRS is a longitudinal nationally representative survey of adults over the age of 50 in the United States. We followed current smokers at baseline (year 1992) until time to first quit. Race/ethnicity was the main predictor; gender, age, education, marital status, count of chronic medical conditions, depressive symptoms, and drinking at baseline were control variables. Cox regression was used for analysis of time to quit. Results Hazard ratios of quitting during the first ten (Hazard ratio = 1.51, p < 0.05) and 20 years (Hazard ratio = 1.46, p < 0.05) were larger for Latinos over the age of 50 compared to Whites. In addition, hazard ratios of quitting during the first 20 years (Hazard ratio = 1.19, p < 0.05) were larger for Blacks over the age of 50 compared to Whites. These findings were partially explained by cigarette consumption intensity, such that Latinos were lighter smokers and therefore more likely to quit than Whites. Conclusion Latinos and Blacks were more likely than Whites to quit smoking cigarettes within 20 years. However, this finding may be explained by cigarette consumption intensity.http://deepblue.lib.umich.edu/bitstream/2027.42/134608/1/12971_2016_Article_90.pd

Nanotechnology in Roman Opaque Red Glass from the 2nd Century AD. Archaeometric Investigation in Red Sectilia from the Decoration of the Lucius Verus Villa in Rome

PD/BD/135053/2017 UID/EAT/00729/2019This work aims to characterise the chemical composition of Roman opaque red glass sectilia dated to the 2nd century A.D and to shed light on Roman glassmaking production of different shades of red, from red to reddish-brown. Due to the lack of technical historical sources for this period many questions about technological aspects still remain. In this project a multi-disciplinary approach is in progress to investigate the red glass sectilia with several red hues from the Imperial Villa of Lucius Verus (161–169 A.D.) in Rome. First, colorimetric measurements were taken to identify the various red hues. The second step was chemical characterization of the samples and the identification of crystalline colouring phases. Particle Induced X-Ray Emission (PIXE) analysis was used to investigate the chemical composition of these glass samples, while the crystalline phases were identified by Raman Spectroscopy and Scanning Electrons Microscope with Energy Dispersive X-ray Spectrometry (SEM-EDS). Using SEM-EDS nanoparticles were detected as a colouring agent, the chemical composition and the morphology of which has been studied in depth. This information has been compared with the colorimetric analysis to establish any correlation with the different colour hues.publishersversionpublishe

SN 1986J VLBI. The Evolution and Deceleration of the Complex Source and a Search for a Pulsar Nebula

We report on VLBI observations of supernova 1986J in the spiral galaxy NGC 891 at two new epochs, 1990 July and 1999 February, t=7.4 and 15.9 yr after the explosion, and on a comprehensive analysis of these and earlier observations from t~4 yr after the explosion date, which we estimate to be 1983.2 +/- 1.1. The source is a shell or composite, and continues to show a complex morphology with large brightness modulations along the ridge and with protrusions. The supernova is moderately to strongly decelerated. The average outer radius expands as t^(0.71 +/- 0.11), and the expansion velocity has slowed to 6000 km/s at t=15.9 yr from an extrapolated 20,000 km/s at t=0.25 yr. The structure changes significantly with time, showing that the evolution is not self-similar. The shell structure is best visible at the latest epoch, when the protrusions have diminished somewhat in prominence and a new, compact component has appeared. The radio spectrum shows a clear inversion above 10 GHz. This might be related to a pulsar nebula becoming visible through the debris of the explosion. The radio flux density between 1.5 and 23 GHz decreases strongly with time, with the flux density proportional to t^(-2.94 +/- 0.24) between t~15 to 19 yr. This decrease is much more rapid than that found in earlier measurements up to t~6 yr.Comment: 24 pages, 9 Figures, LaTeX Accepted for Publication in the Astrophysical Journa

The Density Spike in Cosmic-Ray-Modified Shocks: Formation, Evolution, and Instability

We examine the formation and evolution of the density enhancement (density spike) that appears downstream of strong, cosmic-ray-modified shocks. This feature results from temporary overcompression of the flow by the combined cosmic-ray shock precursor/gas subshock. Formation of the density spike is expected whenever shock modification by cosmic-ray pressure increases strongly. That occurence may be anticipated for newly generated strong shocks or for cosmic-ray-modified shocks encountering a region of higher external density, for example. The predicted mass density within the spike increases with the shock Mach number and with shocks more dominated by cosmic-ray pressure. We find this spike to be linearly unstable under a modified Rayleigh-Taylor instability criterion at the early stage of its formation. We confirm this instability numerically using two independent codes based on the two-fluid model for cosmic-ray transport. These two-dimensional simulations show that the instability grows impulsively at early stages and then slows down as the gradients of total pressure and gas density decrease. Observational discovery of this unstable density spike behind shocks, possibly through radio emission enhanced by the amplified magnetic fields would provide evidence for the existence of strongly cosmic-ray modified shock structures.Comment: 26 pages in Latex and 6 figures. Accepted to Ap

Radio emission and particle acceleration in plerionic supernova remnants

Plerionic supernova remnants exhibit radio emission with remarkably flat spectral indices ranging from $\alpha=0.0$ to $\alpha=-0.3$. The origin of very hard particle energy distributions still awaits an explanation, since shock waves generate particle distributions with synchrotron spectra characterized by $\alpha\le-0.5$. Acceleration of high energy leptons in magnetohydrodynamic turbulence instead may be responsible for the observed hard spectra. This process is studied by means of relativistic test particle calculations using electromagnetic fields produced by three-dimensional simulations of resistive magnetohydrodynamical turbulence. The particles receive power-law energy spectra $N(\gamma)\propto \gamma^{-s}$ with $s$ ranging from 1.2 to 1.6, i.e. particle spectra that are required to explain the radio emission of plerions.Comment: 8 pages, 7 Figures, to be published in A&

Understanding reasons and factors for participation and non-participation to a medication adherence program for patients with diabetic kidney disease in Switzerland: a mixed methods study.

An interprofessional medication adherence intervention led by pharmacists, combining motivational interviews and feedback with electronic monitor (EM) drug assessment, was offered to all consecutive patients with diabetic kidney disease (DKD) (estimated glomerular filtration rate &lt; 60 mL/min/1.73 m &lt;sup&gt;2&lt;/sup&gt; ) visiting their nephrologist or endocrinologist. Approximately 73% (202/275) of eligible patients declined to participate, and the factors and reasons for refusal were investigated. Sociodemographic and clinical data of included patients and those who refused were collected retrospectively for those who had previously signed the general consent form. Multivariate logistic regression analysis was performed to identify independent variables associated with non-participation. Patients who refused or accepted the adherence study were invited to participate in semi-structured interviews. Verbatim transcription, thematic analysis, and inductive coding were performed. Patients who refused to participate were older (n = 123, mean age 67.7 years, SD:10.4) than those who accepted (n = 57, mean age 64.0 years, SD:10.0, p = 0.027) and the proportion of women was higher among them than among patients who accepted it (30.9% vs 12.3%, p = 0.007). The time from diabetes diagnosis was longer in patients who refused than in those who accepted (median 14.2 years IQR 6.9-22.7 vs. 8.6 years, IQR 4.5-15.9, p = 0.003). Factors associated with an increased risk of non-participation were female sex (OR 3.8, 95% CI 1.4-10.0, p = 0.007) and the time from diabetes diagnosis (OR 1.05, 95% CI 1.01-1.09, p = 0.019). The included patients who were interviewed (n = 14) found the interprofessional intervention useful to improve their medication management, support medication literacy, and motivation. Patients who refused to participate and who were interviewed (n = 16) explained no perceived need, did not agree to use EM, and perceived the study as a burden and shared that the study would have been beneficial if introduced earlier in their therapeutic journey. Other barriers emerged as difficult relationships with healthcare providers, lack of awareness of the pharmacist's role, and negative perception of clinical research. Investigating the factors and reasons for participation and non-participation in a study helps tailor intervention designs to the needs of polypharmacy patients. Patients who refused the adherence intervention may not be aware of the benefits of medication management and medication literacy. There is an urgent need to advocate for interprofessional outpatient collaborations to support medication adherence in patients with DKD. Trial registration Clinicaltrials.gov NCT04190251_PANDIA IRIS