FEW SHOT PHOTOGRAMETRY: A COMPARISON BETWEEN NERF AND MVS-SFM FOR THE DOCUMENTATION OF CULTURAL HERITAGE

3D documentation methods for Digital Cultural Heritage (DCH) domain is a field that becomes increasingly interdisciplinary, breaking down boundaries that have long separated experts from different domains. In the past, there has been an ambiguous claim for ownership of skills, methodologies, and expertise in the heritage sciences. This study aims to contribute to the dialogue between these different disciplines by presenting a novel approach for 3D documentation of an ancient statue. The method combines TLS acquisition and MVS pipeline using images from a DJI Mavic 2 drone. Additionally, the study compares the accuracy and final product of the Deep Points (DP) and Neural Radiance Fields (NeRF) methods, using the TLS acquisition as validation ground truth. Firstly, a TLS acquisition was performed on an ancient statue using a Faro Focus 2 scanner. Next, a multi-view stereo (MVS) pipeline was adopted using 2D images captured by a Mini-2 DJI Mavic 2 drone from a distance of approximately 1 meter around the statue. Finally, the same images were used to train and run the NeRF network after being reduced by 90%. The main contribution of this paper is to improve our understanding of this method and compare the accuracy and final product of two different approaches - direct projection (DP) and NeRF - by exploiting a TLS acquisition as the validation ground truth. Results show that the NeRF approach outperforms DP in terms of accuracy and produces a more realistic final product. This paper has important implications for the field of CH preservation, as it offers a new and effective method for generating 3D models of ancient statues. This technology can help to document and preserve important cultural artifacts for future generations, while also providing new insights into the history and culture of different civilizations. Overall, the results of this study demonstrate the potential of combining TLS and NeRF for generating accurate and realistic 3D models of ancient statues

COMPORTAMENTO SUPERPLASTICO DELLA LEGA DI MAGNESIO AZ31 PRODOTTA MEDIANTE “TWIN ROLL CASTING”

Le leghe di Magnesio hanno grandi potenzialità come materiali strutturali, soprattutto per applicazioni nel settore dei trasporti, per il loro basso peso specifico. La scarsa deformabilità a temperatura ambiente ne limita, tuttavia, l’impiego a componenti ottenuti prevalentemente per fusione. Studi recenti hanno evidenziato la possibilità di avere superplasticità in alcune leghe di magnesio, che sarebbero quindi utilizzabili in processi di formatura, per la produzione di componenti near-net-shape di forma complessa. È noto, tuttavia, che il comportamento superplastico è tipicamente rilevabile solo in materiali a microstruttura controllata (grano fine e stabile nel corso della deformazione), quando deformati a temperature e con velocità di deformazione opportune. In questo lavoro sono presentati i risultati di prove di trazione in regime di superplasticità, effettuate sulla lega di magnesio AZ31, prodotta mediante Twin Roll Casting (un processo di colata continua diretta all’interno di due cilindri controrotanti e raffreddati ad acqua) e successivamente laminata a caldo. Il materiale così trattato ha presentato un comportamento superplastico a temperature comprese tra 400 e 420 °C, con un valore massimo dell’allungamento a rottura del 370% a 400 °C e con velocità di deformazione di 1·10-3 s-1. Tali valori sono correlabili alla favorevole microstruttura a grani fini ed equiassici, che favorisce la deformazione controllata dal meccanismo di scorrimento a bordo grano (GBS), come confermato da analisi metallografiche e frattografiche condotte sui campioni deformati

Constitutional trisomy 8 as first mutation in multistep carcinogenesis: clinical, cytogenetic, and molecular data on three cases.

Three patients, with constitutional trisomy 8 mosaicism (CT8M), who developed a malignancy are reported. The diagnoses were refractory anaemia, acute lymphoblastic leukaemia, and idiopathic myelofibrosis. In the child with acute leukaemia, the CT8M was diagnosed at birth due to severe dysmorphisms and malformations; the other two patients showed a milder phenotype, and the CT8M was diagnosed only after the finding of trisomy 8 in neoplastic cells. The review of eight similar, previously reported cases and the clinical, cytogenetic, and molecular studies performed in our patients led us to make the following observations: (1) CT8M predisposes to neoplasms, preferentially to myelo- or lymphoproliferative diseases; (2) a gene dosage effect for glutathione reductase in red blood cells was seen in two of our patients; (3) the wide phenotypic variation of CT8M was confirmed: trisomy 8 in neoplastic cells of phenotypically near-normal cases may be misinterpreted as acquired; and (4) molecular studies suggested a postzygotic origin of the trisomy in our three cases, with the supernumerary chromosome being of paternal origin in one case and of maternal origin in the other two. We postulate that the trisomy 8 in neoplasms may often occur by mitotic nondisjunction in an early embryonic multipotent cell and that what is usually interpreted as an acquired trisomy 8 may in fact be CT8M. The constitutional trisomy 8 would act as a pathogenetically important first mutation in multistep carcinogenesis. Whenever trisomy 8 is found in malignancies, the patient should be reevaluated clinically to exclude CT8M, and CT8M patients should be monitored for the possible development of malignancies

Bancos clonais de Eucalyptus dunnii MAIDEN.

bitstream/item/101091/1/PA-1983-Higa-BancosClonais.pdf.pd

Issues and challenges in the application of Husserlian phenomenology to the Lived Experience of Hate Crime and Its Legal Aftermath

The field of hate crime research addresses the presence, sources and impact of particular types of expressions of prejudice, often perceived as particularly damaging and hurtful forms of interpersonal abuse and violence. Little, if any, credible academic research seeks to vindicate the specific racist, gendered and other vicious prejudices articulated by many perpetrators of hate crime. In turn, this raises the reflexive question of the possibilities of researchers themselves ever being able to adopt a truly "unprejudiced" approach to the presence of such damaging prejudices. Can this goal be realised without a researcher necessarily losing an experientially-grounded understanding of what these meanings, values and purposes have come to mean, and how they are themselves interpretatively re-constituted anew, including within the lived experience of victims, witnesses, police, prosecutors, judges and victim support workers? A possible philosophically-informed approach to the dilemmas posed by this topic is offered by Husserl's phenomenology. Husserl's perpetually unfinished philosophical methodology strives, with concerted if sometimes tragic reflective rigor, to "suspend," "bracket out" and "neutralise" those core presuppositions constitutive of the research field that typically pre-judge precisely whatever demands to be questioned and explored in a radically non-prejudicial manner. This study critically explores the possibilities, reflective stages and theoretical limitations of a sympathetically reconstructed Husserlian approach to hate crime, itself understood as a would-be qualitative "science of consciousness." It argues that despite its manifest tensions, gaps, ambiguities and internal contradictions, aspects of the Husserlian philosophical approach directed towards the different levels of experienced hate crime still retain the potential to both challenge and advance our understanding of this topic. It is the "instructive" part of "instructive failure" that this article highlights

Thin Polymer Brush Decouples Biomaterial's Micro-/Nano-Topology and Stem Cell Adhesion

Surface morphology and chemistry of polymers used as biomaterials, such as tissue engineering scaffolds, have a strong influence on the adhesion and behavior of human mesenchymal stem cells. Here we studied semicrystalline poly(ε-caprolactone) (PCL) substrate scaffolds, which exhibited a variation of surface morphologies and roughness originating from different spherulitic superstructures. Different substrates were obtained by varying the parameters of the thermal processing, i.e. crystallization conditions. The cells attached to these polymer substrates adopted different morphologies responding to variations in spherulite density and size. In order to decouple substrate topology effects on the cells, sub-100 nm bio-adhesive polymer brush coatings of oligo(ethylene glycol) methacrylates were grafted from PCL and functionalized with fibronectin. On surfaces featuring different surface textures, dense and sub-100 nm thick brush coatings determined the response of cells, irrespective to the underlying topology. Thus, polymer brushes decouple substrate micro-/nano-topology and the adhesion of stem cells

Personalizing Cancer Pain Therapy: Insights from the Rational Use of Analgesics (RUA) Group

Introduction: A previous Delphi survey from the Rational Use of Analgesics (RUA) project involving Italian palliative care specialists revealed some discrepancies between current guidelines and clinical practice with a lack of consensus on items regarding the use of strong opioids in treating cancer pain. Those results represented the basis for a new Delphi study addressing a better approach to pain treatment in patients with cancer. Methods: The study consisted of a two-round multidisciplinary Delphi study. Specialists rated their agreement with a set of 17 statements using a 5-point Likert scale (0 = totally disagree and 4 = totally agree). Consensus on a statement was achieved if the median consensus score (MCS) (expressed as value at which at least 50% of participants agreed) was at least 4 and the interquartile range (IQR) was 3–4. Results: This survey included input from 186 palliative care specialists representing all Italian territory. Consensus was reached on seven statements. More than 70% of participants agreed with the use of low dose of strong opioids in moderate pain treatment and valued transdermal route as an effective option when the oral route is not available. There was strong consensus on the importance of knowing opioid pharmacokinetics for therapy personalization and on identifying immediate-release opioids as key for tailoring therapy to patients’ needs. Limited agreement was reached on items regarding breakthrough pain and the management of opioid-induced bowel dysfunction. Conclusion: These findings may assist clinicians in applying clinical evidence to routine care settings and call for a reappraisal of current pain treatment recommendations with the final aim of optimizing the clinical use of strong opioids in patients with cancer

Rivista di Criminologia, Vittimologia e Sicurezza

Con la Rivista di Criminologia, Vittimologia e Sicurezza (RCVS) si intende riflettere su alcune questioni, quali la criminalit\ue0, le sue vittime e i problemi legati alla sicurezza, divenute prioritarie entro la societ\ue0 odierna nella consapevolezza che, sebbene siano aspetti derivanti da fattori diversi, essi richiedono soluzioni integrate, in aperto contrasto con ogni forma di semplificazione e di rigida dicotomia. Infatti, tutte le epoche hanno avvertito di essere in transizione verso qualcosa, tutte hanno avvertito lo scricchiolio del vecchio sotto la pressione di un nuovo ancora imprecisato attraversato da varie forme di vulnerabilit\ue0. La vulnerabilit\ue0, appunto, diviene una possibile chiave di lettura poich\ue9 essa si limita a proporre soluzioni a tinte sfumate, includendo contraddizioni e sollecitando esercizi e prove di approssimazione verso possibili ricerche di sicurezza in un contesto contraddistinto comunque dalla crescente complessit\ue0. Pertanto, tali trasformazioni sociali, in grado di generare nuove possibilit\ue0 di vita e di sviluppo, ma anche di prevaricazione, di sopraffazione, di violenza, influenzano inevitabilmente la formazione di coloro che devono occuparsi di sicurezza e di controllo sociale. Si ritiene quindi che sia di rilevante attualit\ue0, da un punto di vista scientifico e culturale-politico, mettere a disposizione uno spazio entro cui possano confrontarsi criminologi, vittimologi, sociologi, psicologi, pedagogisti, operatori del diritto, studiosi di scienze sociali e giuridiche e esperti della sicurezza per delineare strategie di intervento, in un contesto sociale caratterizzato da complessit\ue0 e ambiguit\ue0, rivolgendo una specifica attenzione alla possibilit\ue0 di riconoscere e di restituire la capacit\ue0 di agire a persone la cui esistenza \ue8 percorsa da processi critici che producono difficolt\ue0 e talvolta disperazione. In questa prospettiva, la Rivista di Criminologia, Vittimologia e Sicurezza potr\ue0 accogliere anche contributi che affrontino gli aspetti teorici della vittimologia senza trascurare l'importanza che riveste, per coloro che a vario titolo sono coinvolti in un processo di aiuto alle vittime, la capacit\ue0 di costruire relazioni e di leggere la realt\ue0 in modo critico e innovativo