PTEN Enters the Nuclear Age

Regulation of the PTEN tumor suppressor protein is poorly understood. In this issue, Wang et al. (2007) and Trotman et al. (2007) describe how ubiquitination regulates PTEN stability and its nuclear localization. Additionally, Shen et al. (2007) report that a nuclear pool of PTEN helps to maintain chromosomal stability

Mothers’ Attitudes about Childhood Nutrition Coverage in Magazines and Newspapers

This study explores mothers’ attitudes toward magazine and newspaper coverage of childhood nutrition issues. The prevalence of childhood obesity has increased in recent years along with media coverage of obesity and obesity issues. This growing concern has posed a problem for society and parents. Focus group interviews and individual interviews were conducted with mothers who read magazines and newspapers. These interviews explored mothers’ nutrition habits, knowledge of obesity and, overall, their attitudes about childhood nutrition topics, such a childhood obesity, as they are presented in magazines and newspapers

Econometric Methods in Staples

statistical models, cross-sectional estimates, fixed effect estimates, panel data

What attracts people with disabilities to pursue a career in clinical psychology?

Although exact numbers are not known, it is clear that the proportion of people with a disability within the UK clinical psychology workforce remains significantly less than within the UK population generally. The aim of this study was to investigate the attractiveness of clinical psychology to people living with a disability who are or are studying to become eligible to apply for professional psychology training. Q methodology was used to analyse patterns in the Q sorts of statements about recruitment incentives and disincentives of thirty three participants. From an exploratory factor analysis of ratings, four narrative interpretations are presented, one for each of four factors identified. Based upon high- and low-rated statements, each narrative demonstrates broad attraction to clinical psychology held in tension with various disincentives. The tensions generated by each narrative probably demand differing degrees of tolerance from potential recruits to apply for training. We conclude critically, wondering whether the profession’s disincentives outweigh its attractors for recruiting staff with a disability. Key Practitioner Message: • Appreciating how potential applicants with a disability may construe clinical psychology, is a step further towards realising a more representative workforce • Self-examination by the UK clinical psychology profession is required to raise awareness of barriers, inadvertent or otherwise, to recruiting staff with a disability

An International Plant Sentinel Network

Invasive plant pests and pathogens pose a major threat to biodiversity around the world, amplified in recent years by the globalisation of trade in plants and plant material and the impacts of climate change. Botanic gardens and arboreta offer a unique opportunity for the identification and further investigation of new and emerging pest and pathogen risks, which can provide valuable information for the creation of prevention, eradication and control programmes. The International Plant Sentinel Network (IPSN) is being developed to provide a platform for coordination, information exchange and support for sentinel plant research within botanic gardens and arboreta. Alongside IPSN Member Gardens, the network includes plant protection professionals and National Plant Protection Organisations (NPPOs) from around the world. The IPSN provides tools which will help to enable gardens to contribute to research by increasing knowledge and awareness among garden staff, developing standardised approaches and providing training materials and methodologies for monitoring and surveying. The network also promotes links with local professional diagnostic support that can help aid the early detection and rapid response to new pest incursions, thus protecting valuable, and often unique, plant collections

The Coming of Conscription in Britain

The subject of this thesis is the conscription debate in Great Britain in the late nineteenth and early twentieth centuries, defined in a social-cultural context. The basic assumption is that a process of cultural conditioning works to determine human actions; actions therefore can be understood by examining cultural conditioning. That examination in this thesis is limited to a study of social and intellectual influences relating to conscription as they acted upon various groups in the English community prior to the Great War. The thesis also discusses the 1915-1916 crisis over actual adoption of conscription, in light of these influences

Shift Change: Minimizing the COVID-19 Nursing Shortage and Decreasing Nursing Burnout

Burnout and the nursing shortage of the healthcare system is not a new issue for nurses, but the COVID-19 pandemic caused this problem to only get worse (Young, 2021). Most healthcare facilities are severely understaffed. The nursing shortage and symptoms of burnout among nurses working in the Intensive Care Units (ICU) and other high-demand COVID-19 nursing units have been magnified by the COVID-19 pandemic. Inferior working conditions such as increased work times, increased workload, and decreased training in the care of COVID-19 patients magnified nursing burnout and the ongoing nursing shortage (Galanis et al., 2021). Discovering ways to reduce the stress and burnout of the nurses working the frontlines of the pandemic is critical to promoting positive mental health of nurses. Some studies have shown there is a correlation between nursing satisfaction and the shift hours worked. Adverse effects such as stress and burnout of nurses, decreased patient outcomes, and lower patient satisfaction reports are associated with nurses working longer hours (Hoedl et al., 2021). The 2023 National Council of State Boards of Nursing (NCSBN) reported that approximately 100,000 Registered Nurses (RNs) left the workforce because of burnout, stress, or retirement during the COVID-19 pandemic. A change is needed to address the ongoing nursing shortage. A prudent, manageable, and cost-efficient way to help reduce nursing burnout is by decreasing the nursing shifts from twelve-hour to eight-hour shifts on high-stress and high- demand nursing units. The PICOT question that will be used for the evidence-based change is the following: In ICU nurses taking care of COVID-19 patients (P), how do eight-hour shifts (I) compared to twelve-hour shifts (C) affect nursing burnout (O) within eight weeks (T)