4,918 research outputs found
Comet and Meteorite Traditions of Aboriginal Australians
Of the hundreds of distinct Aboriginal cultures of Australia, many have oral
traditions rich in descriptions and explanations of comets, meteors,
meteorites, airbursts, impact events, and impact craters. These views generally
attribute these phenomena to spirits, death, and bad omens. There are also many
traditions that describe the formation of meteorite craters as well as impact
events that are not known to Western science.Comment: Encyclopaedia of the History of Science, Technology, and Medicine in
Non-Western Cultures, 2014. Edited by Helaine Selin. Springer Netherland
Colonel Elisha Jones of Weston and the crisis of colonial government in Massachusetts, 1773-1776
This paper contends that without the Tory dimension no factual
account of the Civil War in 1774 and the beginning of the Revolution
in the Colony of Massachusetts Bay is possible, and that there is no
better way of demonstrating actuality in this, as in other historic
problems, than by direct examination of events through the lives of
those who shaped them.
This paper is the first historic study of the last and most
crucial crisis of Colonial Government in Massachusetts - that is,
from the setting up of the Committees of Correspondence in 1772-3
(the Whig extension from Boston of single-party rule by caucus to
supplant the Constitution-Charter of 1691 and political pluralism in
Town Meetings) to the strategic and military victory in the Siege of
Boston of rebellion, created and manipulated by a dedicated Radical
minority, and the enforced withdrawal of the Loyalists, the Loyal
Militia(including Brig. Timothy Ruggles' corps of Loyal Associators)
with the Regular forcer, to Halifax, I. arch 17,1776-as it happened,
and from the experience of one of the most active and prominent of
the largely Tory soldier-Representative-magistrates that since the
Mayflower Compact served as the leaders of Massachusetts: Col. Elisha
Jones (1710-1776), the "famous" Tory squire of Weston, on Charles River
in Middlesex County and less than a day's walk from Boston.
None more than Col. Jones stood for one of the two main Tory
political groups in Massachusetts in the 1770's, the "Reformers, "
so often at cross-purposes with the Hutchinson- Sewall-0liver faction
that supported the status quo and the undivided sovereignty of
Parliament, and who when the Civil War began at the time of the Powder
Alarm,Sept.1,1774, left their homes for Boston, and the fighting of the
Whig political mobs with their weapons of assault and violence to
property to men like Col. Jones, Brig. Ruggles, and Col. Thomas Gilbert
and the Regulars, and who became the early "refugees"in England.
Col. Jones was a leader of the "Reformist" Tories that supported the Constitution-Charter of 1691, and government by law and precedent
in the manner of Blackstone(a best-seller in the Colonies) and who
worked for the greatest measure of "home rule" and needed reforms(such
as adequate pay for judges)initiated whenever possible by the General
Court. Their "Charter" was the Middlesex Magistrates' Address to Gov.
Hutchinson of May, 1774(signed by Col. Jones and possibly drafted by him)
which looked toward an association with Britain based upon mutual
economic and political interest: concepts so forward-looking as not to
he fully accepted until the 20th century, and so dangerous in their own
time as to merit oblivion by the Whigs and vetoes for such measures as
the "Prevention of Bribery and Corruption" bill by Hutchinson. It was
the "Reformers"that carried the burden of resisting the Whig assault
upon the rule of law and maintenance of public order.
One of fewer than a dozen Tories elected to the House in 1773 and
1774, Col. Jones opposed all the unconstitutional Whig measures, including
Committees of Correspondence, impeachment of Chief Justice Oliver and the
Continental Congress. One of the last magistrates to hold court he raised (Nov 1774) one of the first military Tory Corps of the War. Driven to Boston (Dec 1774) by the mobs, he served under Gage and Howe as Forage Commissioner, and three of his sons with Ruggles' Associators. Col. Jones
died in Boston just before the Evacuation, but the ideas he fought for were taken to Nova Scotia and Upper Canada by five of his Tory sons, who with their descendants took a distinguished part of the foundation of a new Empire and
independent nation of Canada
What is the optimal management of partial epilepsy uncontrolled by a first choice anticonvulsant?
Health literacy, health status, and healthcare utilization of Taiwanese adults: results from a national survey
Abstract Background Low health literacy is considered a worldwide health threat. The purpose of this study is to assess the prevalence and socio-demographic covariates of low health literacy in Taiwanese adults and to investigate the relationships between health literacy and health status and health care utilization. Methods A national survey of 1493 adults was conducted in 2008. Health literacy was measured using the Mandarin Health Literacy Scale. Health status was measured based on self-rated physical and mental health. Health care utilization was measured based on self-reported outpatient clinic visits, emergency room visits, and hospitalizations. Results Approximately thirty percent of adults were found to have low (inadequate or marginal) health literacy. They tended to be older, have fewer years of schooling, lower household income, and reside in less populated areas. Inadequate health literacy was associated with poorer mental health (OR, 0.57; 95% CI, 0.35-0.91). No association was found between health literacy and health care utilization even after adjusting for other covariates. Conclusions Low (inadequate and marginal) health literacy is prevalent in Taiwan. High prevalence of low health literacy is not necessarily indicative of the need for interventions. Systematic efforts to evaluate the impact of low health literacy on health outcomes in other countries would help to illuminate features of health care delivery and financing systems that may mitigate the adverse health effects of low health literacy.http://deepblue.lib.umich.edu/bitstream/2027.42/78252/1/1471-2458-10-614.xmlhttp://deepblue.lib.umich.edu/bitstream/2027.42/78252/2/1471-2458-10-614.pdfPeer Reviewe
Safety aspects of infliximab in inflammatory bowel disease patients - A retrospective cohort study in 100 patients of a German University Hospital
Background: Infliximab, a chimeric anti-tumour necrosis factor monoclonal antibody with potent anti-inflammatory effects, represents an effective treatment option in patients with severe inflammatory bowel disease (IBD). Serious side-effects of such an immunomodulating therapy are speculated and therefore we reviewed our clinical experience in a retrospective safety study looking upon a single cohort of 100 IBD patients from a large German University Hospital. Methods: 100 patients with severe Crohn's disease (n = 92), ulcerative colitis (n = 7) or indeterminate colitis (n = 1) treated with infliximab (5 mg/kg) from January 2000 to December 2003 were retrospectively analysed for acute and subacute adverse events by chart review. Results: Overall, infliximab therapy was generally well tolerated. No fatal complications, malignancies, autoimmune diseases, neurologic or cardiovascular complications were observed in the cohort during the study period. Overall, adverse events were observed in 10 patients: 2 patients showed an acute infusion reaction, 1 patient a serum sickness-like reaction, in 4 patients a bacterial or viral infection occurred, in 1 patient pancytopenia and 2 patients developed surgical complications. Only 6 patients with adverse events required admission to hospital. A case of tuberculosis after infliximab was not found. The lack of adverse side-effects was associated with young median age and infrequent comorbidities of the cohort. Conclusion: Regarding its strong immunomodulating capacity, infliximab appears to be an efficient and relatively safe therapeutic option for patients with severe IBD. However, the use of infliximab requires careful screening and close patient monitoring to identify patients at risk and the infrequent, but sometimes serious complications of infliximab. Copyright (C) 2004 S. Karger AG, Basel
Validation of Self-Reported Health Literacy Questions Among Diverse English and Spanish-Speaking Populations
BackgroundLimited health literacy (HL) contributes to poor health outcomes and disparities, and direct measurement is often time-intensive. Self-reported HL questions have not been validated among Spanish-speaking and diverse English-speaking populations.ObjectiveTo evaluate three self-reported questions: 1 "How confident are you filling out medical forms?"; 2 "How often do you have problems learning about your medical condition because of difficulty understanding written information?"; and 3 "How often do you have someone help you read hospital materials?" Answers were based on a 5-point Likert scale.DesignThis was a validation study nested within a trial of diabetes self-management support in the San Francisco Department of Public Health.ParticipantsEnglish and Spanish-speaking adults with type 2 diabetes receiving primary care.MethodsUsing the Test of Functional Health Literacy in Adults (s-TOFHLA) in English and Spanish as the reference, we classified HL as inadequate, marginal, or adequate. We calculated the C-index and test characteristics of the three questions and summative scale compared to the s-TOFHLA and assessed variations in performance by language, race/ethnicity, age, and education.Key resultsOf 296 participants, 48% were Spanish-speaking; 9% were White, non-Hispanic; 47% had inadequate HL and 12% had marginal HL. Overall, 57% reported being confident with forms "somewhat" or less. The "confident with forms" question performed best for detecting inadequate (C-index = 0.82, (0.77-0.87)) and inadequate plus marginal HL (C index = 0.81, (0.76-0.86); p<0.01 for differences from other questions), and performed comparably to the summative scale. The "confident with forms" question and scale also performed best across language, race/ethnicity, educational attainment, and age.ConclusionsA single self-reported HL question about confidence with forms and a summative scale of three questions discriminated between Spanish and English speakers with adequate HL and those with inadequate and/or inadequate plus marginal HL. The "confident with forms" question or the summative scale may be useful for estimating HL in clinical research involving Spanish-speaking and English-speaking, chronically-ill, diverse populations
No Detectable Fertility Benefit from a Single Additional Mating in Wild Stalk-Eyed Flies
Background: Multiple mating by female insects is widespread, and the explanation(s) for repeated mating by females has been the subject of much discussion. Females may profit from mating multiply through direct material benefits that increase their own reproductive output, or indirect genetic benefits that increase offspring fitness. One particular direct benefit that has attracted significant attention is that of fertility assurance, as females often need to mate multiply to achieve high fertility. This hypothesis has never been tested in a wild insect population.Methodology/Principal Findings: Female Malaysian stalk-eyed flies (Teleopsis dalmanni) mate repeatedly during their lifetime, and have been shown to be sperm limited under both laboratory and field conditions. Here we ask whether receiving an additional mating alleviates sperm limitation in wild females. In our experiment one group of females received a single additional mating, while a control group received an interrupted, and therefore unsuccessful, mating. Females that received an additional mating did not lay more fertilised eggs in total, nor did they lay proportionately more fertilised eggs. Female fertility declined significantly through time, demonstrating that females were sperm limited. However, receipt of an additional mating did not significantly alter the rate of this decline.Conclusions/Significance: Our data suggest that the fertility consequences of a single additional mating were small. We discuss this effect (or lack thereof), and suggest that it is likely to be attributed to small ejaculate size, a high proportion of failed copulations, and the presence of X-linked meiotic drive in this species
The relationship between literacy and multimorbidity in a primary care setting
<p>Abstract</p> <p>Background</p> <p>Multimorbidity is now acknowledged as a research priority in primary care. The identification of risk factors and people most at risk is an important step in guiding prevention and intervention strategies. The aim of this study was to examine the relationship between literacy and multimorbidity while controlling for potential confounders.</p> <p>Methods</p> <p>Participants were adult patients attending the family medicine clinic of a regional health centre in Saguenay (Quebec), Canada. Literacy was measured with the Newest Vital Sign (NVS). Multimorbidity was measured with the Disease Burden Morbidity Assessment (DBMA) by self-report. Information on potential confounders (age, sex, education and family income) was also collected. The association between literacy (independent variable) and multimorbidity was examined in bivariate and multivariate analyses. Two operational definitions of multimorbidity were used successively as the dependent variable; confounding variables were introduced into the model as potential predictors.</p> <p>Results</p> <p>One hundred three patients (36 men) 19–83 years old were recruited; 41.8% had completed 12 years of school or less. Forty-seven percent of patients provided fewer than four correct answers on the NVS (possible low literacy) whereas 53% had four correct responses or more. Literacy and multimorbidity were associated in bivariate analyses (p < 0.01) but not in multivariate analyses, including age and family income.</p> <p>Conclusion</p> <p>This study suggests that there is no relationship between literacy and multimorbidity when controlling for age and family income.</p
Development of a reliable and construct valid measure of nutritional literacy in adults
BACKGROUND: Research into the relation of literacy to health status has not included measures of nutritional literacy. This may be a critical area in the study of chronic conditions such as hypertension and diabetes, which can both relate to obesity and nutrition. This paper details the development and psychometric characteristics of the Nutritional Literacy Scale (NLS), offered as a measure of adults' ability to comprehend nutritional information. METHODS: In order to assess the internal consistency and construct validity of the NLS, demographic data, readability statistics, NLS scores and scores on the Reading Comprehension Section of the Short Test of Functional Health Literacy in Adults (S-TOFHLA) were collected in a cross-sectional study of 341 patients from two primary care practices. RESULTS: The NLS score showed acceptable internal consistency of 0.84 by Cronbach's alpha coefficient. The Pearson correlation between the NLS and the S-TOFHLA was 0.61, supporting evidence for construct validity. CONCLUSION: Given the importance of proper weight and nutrition in the health of the public, as well as the absence of research on literacy skills as related to nutritional concepts, the NLS has the potential to add to the national research agenda in these areas
The development of health literacy in patients with a long-term health condition: the health literacy pathway model
Background
Inadequate health literacy has been associated with poor management of long-term health conditions and has been identified as a key social determinant of health outcomes. However, little is understood about how health literacy might develop over time or the processes by which people may become more health literate. Our objectives were to describe how patients with a long-term condition practice health literacy in the management of their health and communication with health professionals, how they become more health literate over time and their experience of using health services. We also sought to identify and describe the motivations, facilitators and barriers in the practice of health literacy in healthcare consultations.
Methods
We designed a longitudinal qualitative study using serial interviews with 18 participants to explore their experiences of learning to manage their condition and their experiences of health literacy when participating in healthcare processes. Participants were recruited from patient education programmes and were interviewed three times over a period of 9 months. A framework approach was used to analyse data.
Results
A model is presented that illustrates the development of health literacy along a trajectory that includes the development of knowledge, health literacy skills and practices, health literacy actions, abilities in seeking options and informed and shared decision making opportunities. Motivations and barriers to developing and practising health literacy skills partly reflected participants' characteristics but were also influenced by health professionals. Some participants developed their health literacy to a point where they became more involved in healthcare processes (including informed and shared decision-making).
Conclusions
Patients with a long-term condition can develop health literacy skills over time and put their skills into practice in becoming more active in healthcare consultations. Our findings have implications for developing health literacy interventions aimed at patient involvement in healthcare processes and improved self-management of long-term conditions
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