583 research outputs found
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A moving-mesh finite element method and its application to the numerical solution of phase-change problems
A distributed Lagrangian moving-mesh finite element method is applied to problems involving changes of phase. The algorithm uses a distributed conservation principle to determine nodal mesh velocities, which are then used to move the nodes. The nodal values are obtained from an ALE (Arbitrary Lagrangian-Eulerian) equation, which represents a generalization of the original algorithm presented in Applied Numerical Mathematics, 54:450--469 (2005). Having described the details of the generalized algorithm it is validated on two test cases from the original paper and is then applied to one-phase and, for the first time, two-phase Stefan problems in one and two space dimensions, paying particular attention to the implementation of the interface boundary conditions. Results are presented to demonstrate the accuracy and the effectiveness of the method, including comparisons against analytical solutions where available
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Solved! Making the case for collaborative problem-solving
This report argues that the ability to solve problems with others is a crucial skill for our young people in the workplace of the future but the current education system does little to support it. Key findings Collaborative problem-solving (CPS) is an increasingly important skill to teach young people in order to prepare them for the future. Despite strong evidence for its impact, CPS is rarely taught in schools but if structured well it can reinforce knowledge and improve attainment. Significant barriers exist for teachers implementing this practice, from behaviour management to curriculum coverage, to task-design. For CPS to gain ground, a concerted shift is needed including teacher training, better resources and system level support. This report is part of Nesta’s ongoing commitment to equipping young people with the skills they need to succeed. It makes a series of recommendations on how organisations and policymakers can help support and embrace the implementation of CPS. Nesta is following this up with a series of small-scale pilots of aligned programmes in order to evaluate impact and explore how CPS can be implemented in a range of practical settings. Policy recommendations Stimulate production of quality collaborative problem-solving (CPS) resources and training, from primary education onwards. Fund existing, aligned programmes to scale and evaluate impact. Educate and involve the out-of-school learning sector and volunteer educators. Develop smarter collaborative problem-solving assessment methods. Help higher education organisations and MOOCs to track what works
\u3ci\u3eAcrobasis\u3c/i\u3e Shoot Moth (Lepidoptera: Pyralidae) Infestation-Tree Height Link in a Young Black Walnut Plantation
Acrobasis shoot moth infestations were evaluated in a young black walnut progeny test for 4 years, from ages 3 to 6. Infestation levels were greatest on the largest trees in the fourth and fifth year after plantation establishment, and were declining by the sixth year. Acrobasis infestation appears to be a problem primarily on young trees less than 2.5 m in height. There was no evidence for genetic resistance to Acrobasis infestation in black walnut
Regulation of synaptic connectivity: levels of fasciclin II influence synaptic growth in the Drosophila CNS
Much of our understanding of synaptogenesis comes from studies that deal with the development of the neuromuscular junction (NMJ). Although well studied, it is not clear how far the NMJ represents an adequate model for the formation of synapses within the CNS. Here we investigate the role of Fasciclin II (Fas II) in the development of synapses between identified motor neurons and cholinergic interneurons in the CNS of Drosophila. Fas II is a neural cell adhesion molecule homolog that is involved in both target selection and synaptic plasticity at the NMJ in Drosophila. In this study, we show that levels of Fas II are critical determinants of synapse formation and growth in the CNS. The initial establishment of synaptic contacts between these identified neurons is seemingly independent of Fas II. The subsequent proliferation of these synaptic connections that occurs postembryonically is, in contrast, significantly retarded by the absence of Fas II. Although the initial formation of synaptic connectivity between these neurons is seemingly independent of Fas II, we show that their formation is, nevertheless, significantly affected by manipulations that alter the relative balance of Fas II in the presynaptic and postsynaptic neurons. Increasing expression of Fas II in either the presynaptic or postsynaptic neurons, during embryogenesis, is sufficient to disrupt the normal level of synaptic connectivity that occurs between these neurons. This effect of Fas II is isoform specific and, moreover, phenocopies the disruption to synaptic connectivity observed previously after tetanus toxin light chain-dependent blockade of evoked synaptic vesicle release in these neurons
A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions
Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA viruses. However, such machinery is well characterized in tailed bacteriophage, which share a common evolutionary origin with herpesvirus. In tailed bacteriophage, the genome exits from the virus particle through a portal and is transferred into the host cell by a complex apparatus (i.e. the tail) located at the portal vertex. Here we use electron cryo-tomography of human herpes simplex type-1 (HSV-1) virions to reveal a previously unsuspected feature at the portal vertex, which extends across the HSV-1 tegument layer to form a connection between the capsid and the viral membrane. The location of this assembly suggests that it plays a role in genome release into the nucleus and is also important for virion architecture
Understanding the independent dancer: roles, development and success
Little research has been published about the varied role of the independent dancer. The aim of this study was to provide insight into the work independent dancers undertake and how their careers change over time. Semi-structured interviews were conducted with 14 independent dancers. Content analysis revealed that the dancers had multifaceted careers that relied on both formal and informal activities, and varied according to three distinct stages (early, middle, late). The experiences reported by the dancers indicated that the realities of the independent dancer's role are not sufficiently recognised or supported within the industry
The age of the directly imaged planet host star k Andromedae determined from interferometric observations
κ Andromedae, an early-type star that hosts a directly imaged low-mass companion, is expected to be oblate due to its rapid rotational velocity (v sin i = ~162 km s⁻¹). We observed the star with the CHARA Array's optical beam combiner, PAVO, measuring its size at multiple orientations and determining its oblateness. The interferometric measurements, combined with photometry and this v sin i value are used to constrain an oblate star model that yields the fundamental properties of the star and finds a rotation speed that is ~85% of the critical rate and a low inclination of ~30°. Three modeled properties (the average radius, bolometric luminosity, and equatorial velocity) are compared to MESA evolution models to determine an age and mass for the star. In doing so, we determine an age for the system of 47_₄₀⁺²⁷ Myr. Based on this age and previous measurements of the companion's temperature, the BHAC15 evolution models imply a mass for the companion of 22_₉⁺⁸ MJ.This work is based upon observations
obtained with the Georgia State University Center for High
Angular Resolution Astronomy Array at Mount Wilson
Observatory. The CHARA Array is supported by the National
Science Foundation under grants AST-1211929 and AST-
1411654. Institutional support has been provided from the
GSU College of Arts and Sciences and the GSU Office of the
Vice President for Research and Economic Development. J.J.
and R.J.W. acknowledge support from NSF AAG grants
1009643 and 1517762
Grid-Based Atmospheric Retrievals for Reflected-Light Spectra of Exoplanets using PSGnest
Techniques to retrieve the atmospheric properties of exoplanets via direct
observation of their reflected light have often been limited in scope due to
computational constraints imposed by the forward-model calculations. We have
developed a new set of techniques which significantly decreases the time
required to perform a retrieval while maintaining accurate results. We
constructed a grid of 1.4 million pre-computed geometric albedo spectra valued
at discrete sets of parameter points. Spectra from this grid are used to
produce models for a fast and efficient nested sampling routine called PSGnest.
Beyond the upfront time to construct a spectral grid, the amount of time to
complete a full retrieval using PSGnest is on the order of seconds to minutes
using a personal computer. An extensive evaluation of the error induced from
interpolating intermediate spectra from the grid indicates that this bias is
insignificant compared to other retrieval error sources, with an average
coefficient of determination between interpolated and true spectra of 0.998. We
apply these new retrieval techniques to help constrain the optimal bandpass
centers for retrieving various atmospheric and bulk parameters from a
LuvEx-type mission observing several planetary archetypes. We show that
spectral observations made using a 20\% bandpass centered at 0.73 microns can
be used alongside our new techniques to make detections of and
without the need to increase observing time beyond what is necessary for a
signal-to-noise ratio of 10. The methods introduced here will enable robust
studies of the capabilities of future observatories to characterize exoplanets.Comment: 32 pages, 17 figures. Accepted for publication in The Astronomical
Journa
The microbiome of the marine flatworm Macrostomum lignano provides fitness advantages and exhibits circadian rhythmicity
AbstractThe close association between animals and their associated microbiota is usually beneficial for both partners. Here, we used a simple marine model invertebrate, the flatworm Macrostomum lignano, to characterize the host-microbiota interaction in detail. This analysis revealed that the different developmental stages each harbor a specific microbiota. Studies with gnotobiotic animals clarified the physiological significance of the microbiota. While no fitness benefits were mediated by the microbiota when food was freely available, animals with microbiota showed significantly increased fitness with a reduced food supply. The microbiota of M. lignano shows circadian rhythmicity, affecting both the total bacterial load and the behavior of specific taxa. Moreover, the presence of the worm influences the composition of the bacterial consortia in the environment. In summary, the Macrostomum-microbiota system described here can serve as a general model for host-microbe interactions in marine invertebrates.</jats:p
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