171 research outputs found

    Securing future decentralised industrial IoT infrastructures: challenges and free open source solutions

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    peer-reviewedThe next industrial revolution is said to be paved by the use of novel Internet of Things (IoT) technology. One important aspect of the modern IoT infrastructures is decentralised communication, often called Peer-to-Peer (P2P). In the context of industrial communication, P2P contributes to resilience and improved stability for industrial components. Current industrial facilities, however, still rely on centralised networking schemes which are considered to be mandatory to comply with security standards. In order to succeed, introduced industrial P2P technology must maintain the current level of protection and also consider possible new threats. The presented work starts with a short analysis of well-established industrial communication infrastructures and how these could benefit from decentralised structures. Subsequently, previously undefined Information Technology (IT) security requirements are derived from the new cloud based decentralised industrial automation model architecture presented in this paper. To meet those requirements, state-of-the-art communication schemes and their open source implementations are presented and assessed for their usability in the context of industrial IoT. Finally, derived building blocks for industrial IoT P2P security are presented which are qualified to comply with the stated industrial IoT security requirements

    Genetic landscape and clinical outcomes of patients with <i>BCOR</i> mutated myeloid neoplasms

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    The BCL6-corepressor (BCOR) is a tumor-suppressor gene located on the short arm of chromosome X. Data are limited regarding factors predicting survival in BCOR-mutated (mBCOR) acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). We evaluated 138 patients with mBCOR myeloid disorders, of which 36 (26.1%) had AML and 63 (45.6%) had MDS. Sixty-six (47.8%) patients had a normal karyotype while 18 (13%) patients had complex karyotype. BCOR-mutated MDS/AML were highly associated with RUNX1 and U2AF1 co-mutations. In contrast, TP53 mutation was infrequently seen with mBCOR MDS. Patients with an isolated BCOR mutation had similar survival compared to those with high-risk co-mutations by European LeukemiaNet (ELN) 2022 criteria (median OS 1.16 vs. 1.27 years, P=0.46). Complex karyotype adversely impacted survival among mBCOR AML/MDS (HR 4.12, P<0.001), while allogeneic stem cell transplant (alloSCT) improved survival (HR 0.38, P=0.04). However, RUNX1 co-mutation was associated with an increased risk of post-alloSCT relapse (HR 88.0, P=0.02), whereas melphalan-based conditioning was associated with a decreased relapse risk (HR 0.02, P=0.01). We conclude that mBCOR is a high-risk feature across MDS/AML, and that alloSCT improves survival in this population

    Technologies for context based video search

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    This thesis presents methods and a system for video search over the internet or the intranet. The objective is to design a real time and automated video clustering and search system that provides users of the search engine the most relevant videos available that are responsive to a query at a particular moment in time, and supplementary information that may also be useful. The thesis highlights methods to mitigate the effect of the semantic gap faced by current content based video search approaches. A context-sensitive video ranking scheme is used, wherein the context is generated in an automated manner.M.S.Committee Chair: Madisetti, Vijay; Committee Member: Navathe, Shamkant; Committee Member: Yalamanchili, Sudhaka

    An account of critical regionalism in diverse building types in postcolonial Indian architecture

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    Critical regionalism is an architectural concept that seeks to balance local needs and capabilities with the progressive lessons of modernisation. Critical regionalism has been an influential architectural approach in postcolonial Indian architecture. Even before the term was coined in the 1980s, architects in India had subconsciously begun pursuing the ideas of critical regionalism in designing their buildings. The degree of influence of critical regionalism on postcolonial Indian architecture has varied over the course of time as a result of economic, political and social changes. This paper identifies key architectural projects realised in India since 1947 that adhere to the ideas and principles of critical regionalism. The identified regionalist projects have been categorised according to their building programmes and significant examples in each building type are discussed chronologically while bringing forth their qualities that make them regionalist in first place. By focussing on regionalist projects of significance in each building type, the paper highlights that critical regionalism is capable of producing potent architecture to cater to any building programme. Keywords: Critical regionalism, Postcolonial architecture, Indian architectur

    A Study of Regional Assertions in the Architecture of Delhi from the 1970s to the present

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    Critical regionalism is an architectural approach that seeks to correct sterile and abstract modernism by using contextual forces that focus on local needs and potential. As globalisation disrupts and displaces local building traditions in India&rsquo;s metropolitan cities, critical regionalism offers resistance to the homogenising forces of global modernism. This paper analyses five key architectural works realised in Delhi in the past four decades that incorporate the ideas of critical regionalism in their designs. The different approaches adopted by regionalist architects in dealing with local climate, topography, materials and sociological complexes have been presented. By limiting itself to regionalist works in Delhi, the paper attempts to highlight that critical regionalism is not a set of aesthetic preferences but a philosophical framework capable of producing diverse forms of architecture despite analogous external influences arising from similar site conditions

    A Study of Regional Assertions in the Architecture of Delhi from the 1970s to the present

    No full text
    Critical regionalism is an architectural approach that seeks to correct sterile and abstract modernism by using contextual forces that focus on local needs and potential. As globalisation disrupts and displaces local building traditions in India&#8217;s metropolitan cities, critical regionalism offers resistance to the homogenising forces of global modernism. This paper analyses five key architectural works realised in Delhi in the past four decades that incorporate the ideas of critical regionalism in their designs. The different approaches adopted by regionalist architects in dealing with local climate, topography, materials and sociological complexes have been presented. By limiting itself to regionalist works in Delhi, the paper attempts to highlight that critical regionalism is not a set of aesthetic preferences but a philosophical framework capable of producing diverse forms of architecture despite analogous external influences arising from similar site conditions

    Internet of things: A hands-on approach

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    s.l.433 p.: bibl., index; 25 c

    Knowledge Acquisition for Electronic Health Records on cloud

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