Analisis Strategi Promosi Kesehatan di Puskesmas Bambalamotu dalam Pembinaan Masyarakat Suku Daa di Desa Kasoloang Kab.mamuju Utara

The This research is qualitative one that aimed to analyse strategy of health promotion through advocacy held by Center of The Society Health Bambalamotu in social construction of Tribe Daa in Wulai, North Mamuju. The selected informan was field worker of Center of The Society Health, leader of Center of The Society Health, cadre of countryside and society health by getting information through in depth interview, observation and FGD. The result of research showed that, for advocacy with Center of The Society Health through Inwrought Service Post, Circling Countryside Post, Ministrant of Centre of Health Society. Social support that was preparation to become cadre of health and society enablement was done by cadre of Inwrought Service Post in the form of counseling from government or social enablement institute and missioner (church). Suggested to the society ministrant in Clean and Healthy Life Style and other partnership, Social Enablement Institute and other society.Key Word : Health Promotion, Social Education, Tribe Da

Moringa Leaves Extract on Food Intake and Weight Gain of Pregnant Women Working in Informal Sector

Background : The research aimed to determine the effect of Moringa leaves extract on food intake and body weight of pregnant women who are working in nformal sector. This research was carried out in 4 local government clinics in Manggala district (Puskesmas) in Batua, Antang, Perumnas Antang and Tamangapa. Method : This study was a double blind randomized controlled with pregnant women who were generally working as trader in traditional market. Subject divided into 2 group with intervention group (n=35) received extract Moringa leaves together with Fe tablet for 3 months and control group (n=33) received only Fe tablet. Food consumption and body weight were collected by well-trained field workers. T-test was used to measure the mean difference of the increased of food intake and weight gain between groups. Result : The results showed that characteristic of subject was not difference before intervention (P>0,05). After intervention, the results indicatedthatenergyintakeandfolicaciddecreasedin both groupswith highersignificant reduction on control group (p<0.05), butthe decreased was not significantlydifferent(p>0.05). Intake of protein, iron, andfiberalsodecreased in both group,butnot significant (p>0.05). VitaminCandEintake decreasedin both groupswith agreater significant reductionin intervention group (p<0.05), butthe difference of decreasedwas not significant(p>0.05). Zinc intake increasedon intervention groupanddecreasedon control groupthatwere notsignificant, however,the comparisonamong the groupsshows significant differences (p<0.05). Beside that, Body weight seen increased in both intervension groups (56,06 ± 9,86 to 61,23 ± 9,85, p=0,000) nor control groups(58,66 ± 10,07 to 61,74 ± 9,86, p=0,000)and seen a significant difference for weight gain between two groups. Conclusion : Moringa leaves extract can increasedweight gain but not for food intake of pregnant women informal sector workers

Pengaruh antara Penggunaan Teknologi Informasi, Implementasi Strategi Diferensiasi, dan Kualitas Layanan dalam Mencapai Keunggulan Bersaing pada Rumah Sakit Haji Makassar

Perkembangan persaingan antar Perusahaan semakin ketat baik pada tingkat regional maupun global. Pada sebagian besar industri jasa, kualitas layanan secara umum diterima sebagai suatu faktor penentu (key factor). Zeithaml dan Berry menyatakan bahwa kualitas layanan merupakan strategi yang mendasar dalam upaya Perusahaan meraih sukses dan keberlanjutan dalam lingkungan bisnis yang ketat. Kualitas pelayanan dapat dipengaruhi oleh faktor-faktor seperti penggunaan teknologi informasi dan implementasi strategi diferensiasi. Tujuan penelitian ini adalah untuk menganalisis pengaruh penggunaan teknologi informasi terhadap kualitas pelayanan, pengaruh kualitas pelayanan terhadap keunggulan bersaing, dan pengaruh implementasi strategi diferensiasi terhadap keunggulan bersaing. Penelitian ini merupakan penelitian explanatory adalah untuk menjelaskan hubungan kausal antara variabel melalui proposisi konfirmatory dan pengujian. Dalam penelitian ini teknik analisis yang digunakan Structural Equation Modelling (SEM). Perwakilan jumlah sampel yang digunakan dalam penelitian yang sesuai dengan menggunakan teknik analisis SEM.Teknologi informasi memiliki pengaruh positif dan signifikan terhadap kualitas pelayanan, strategi diferensiasi memiliki pengaruh positif dan signifikan terhadap keunggulan kompetitif, kualitas layanan memiliki pengaruh positif dan signifikan terhadap keunggulan kompetitif. Teknologi informasi dan strategi diferensiasi dapat memengaruhi kualitas pelayanan dan kualitas pelayanan itu sendiri akan memengaruhi keunggulan bersaing rumah sakit. Kesimpulannya adalah penggunaan teknologi informasi berpengaruh positif dan signifikan terhadap kualitas pelayanan sedangkan strategi diferensiasi dan kualitas layanan berpengaruh positif dan signifikan terhadap keunggulan bersaing

The Relationship Between Food Pattern and Hemoglobin Level in Pregnant Women at Maros, South Sulawesi

Food consumption pattern is known as a determinant factor for nutritional problems among pregnant mothers. This study was intended to assess food consumption and its relationship to anemia in Maros Districts, Indonesia. This study was conducted in two sub-districts and pregnant mothers was randomly selected (n = 200) and proportionally from both districts. Data was collected by train field workers including measurement of hemoglobin, height and weight, 24-hour recall and food frequency questionnaire. Multivariate analyses were performed to see the relationship between food consumption and anemia. It showed that anemia prevalence was 41% whereas mostly in mild and moderate levels (44% and 55% respectively). The most common pattern of food consumption was rice, fish, and some vegetables. However, vegetables and fruit mostly consumed only 3-6 time a week. Energy and protein intakes were only 59% to 72% recommended dietary allowance (RDA) or 1300 kcal and 48 gr respectively. Most vitamin was consumed only around 40% except for vitamin A (76%, 605 RE), folic acid (195%, 1170 ug), and Vitamin B12 (142%, 3,7 ug). However, iron and zinc intakes were only 6.1 gr (17.5% RDA) and 5.9 gr (44% RDA), respectively. Multivariate analyses showed that education duration of mothers, nutritional status, iron tablet intakes, vitamin C, and B6 consumption were significantly related to anemia of pregnant mothers in the study and accounted for 24% (p<0.05). We conclude that food consumption was relatively low and caused lack intakes for both macro and micro nutrients of pregnant mothers in the  study. Education and nutritional status of the mothers contributed also to the anemia prevalence

Relation Expression of Eestrogen Reseptor and Ki67 in Invasive Ductal Carcinoma Breast Cancer

Estrogen are potent mitogenic stimuli that share important properties in the control of cellular proliferation. Increased expression and/or activity of estrogen reseptor (ER) result in aberrant activation of downstream signaling pathways including cAMP/PKA, MAPK/ERK and PI3K/AKT. The importance of estrogen and as a signaling axis in cancer development, progression and metastasis is highlighted by its effects on cancer cells, notably proliferation

The Correlation Between Level of C-Reactive Protein and Radiographic Grading of Knee Osteoarthritis

Introductions. Several studies have shown that the acute phase response may take place in osteoarthritis, suggesting that low grade systemic inflammation may be present in patients with osteoarthritis. Materials and methods. This study was aimed to measure the c-reactive protein level of knee osteoarthritis, to determine radiographic grading of knee osteoarthritis according to Kellgren-Lawrence grading, and to determine correlation between level of c-reactive protein and radiographic grading of knee osteoarthritis. This study used observational cross sectional design. Samples were 65 postmenopausal women with clinical knee osteoarthritis, aged 50 to 70 years old. Clinical and radiologic diagnoses of knee osteoarthritis were determined by clinical and radiographic examination with AP weight bearing position. Grade <3, grade 3 and grade 4 were radiographic grading of knee osteoarthritis according to Kellgren-Lawrence classification. Results. From 65 samples, 28 (43%) samples had grade < 3 with level of c-reactive protein 0.2-1.0 mg/dl (0.54±0.23 mg/dl), 22 (34%) samples had grade 3 with level of c-reactive protein 0.3-1.4 mg/dl (0.70±0.33 mg/dl) and 15 (23%) samples had grade 4 with level of c-reactive protein 0.3 -1.3 mg/dl (0.80±0.26 mg/dl). The cumulative of level of c-reactive protein was 0.2-1.4 mg/dl (0.65±0.29 mg/dl). There is correlation between level of c-reactive protein and radiographic grading of knee osteoarthritis (p=0.04), with Spearman rho correlation of 0.349 and α=5%. The level of c-reactive protein in grade <3, grade 3 and grade 4 overlaps, so the level of c-reactive protein could not be used to determine radiographic grading of knee osteoarthritis. Conclusions. There is no correlation between level of c-reactive protein and radiographic grading of knee osteoarthritis, there is a tendency that the level of c-reactive protein is higher in high grade knee osteoarthritis

FORMULASI DAN ANALISIS KANDUNGAN MIKRONUTRIEN SERTA AKTIVITAS ANTIOKSIDAN SELAI LEMBARAN ALBEDO SEMANGKA DAN KULIT BUAH NAGA SEBAGAI ALTERNATIF PENCEGAHAN HIPERTENSI : FORMULATION AND ANALYSIS OF MICRONUTRIENT AND ANTIOXIDANT ACTIVITY OF WATERMELON ALBEDO AND DRAGON FRUIT PEEL- BASED SHEET JAM AS AN ALTERNATIVE TO PREVENTING HYPERTENSION

Pendahuluan: Menurut hasil Riskesdas tahun 2018, prevalensi hipertensi di Indonesia mencapai 34,1%. Albedo semangka dan kulit buah naga merupakan buah yang banyak mengandung tinggi kalium dan vitamin C namun rendah natrium. Tujuan: Penelitian ini bertujuan untuk mengetahui kandungan mikronutrien dan aktivitas antioksidan selai lembaran berbasis albedo semangka dan kulit buah naga. Bahan dan Metode: Desain penelitian ini adalah eksperimental laboratorium. Pada formula terpilih, dilakukan analisis mikronutrien berupa natrium, kalium dan vitamin C serta aktivitas antioksidan. Analisis natrium dan kalium dilakukan dengan metode AAS (Atomic Absorbtion Spektrofotometer), analisis vitamin C menggunakan metode Titrasi Iodometri, sedangkan analisis aktivitas aktioksidan dilakukan dengan metode DPPH. Hasil: Kandungan zat gizi pada formula terpilih selai lembaran berbasis albedo semangka dan kulit buah naga per 45 gram atau satu porsi, yaitu sebesar 10,81 mg natrium, 122,99 mg kalium, 14,19 mg vitamin C. Nilai Inhibition Concentration (IC50) sebesar 341,53 ppm (aktivitas antioksidan sangat lemah). 1 lembar/porsi selai lembaran albedo semangka dan kulit buah naga dapat memenuhi 0,77% kebutuhan natrium, 2,61% kebutuhan kalium dan 18,92% kebutuhan vitamin C berdasarkan AKG pada wanita dewasa akhir berusia 50-64 tahun. Kesimpulan: Selai lembaran albedo semangka mengandung natrium lebih rendah, kalium lebih tinggi dan vitamin C lebih tinggi dibandingkan dengan selai pada umumnya. Dibutuhkan pengembangan lebih lanjut agar masyarakat, dapat menjadikan selai lembaran albedo semangka dan kulit buah naga sebagai alternatif selai yang rendah natrium, tinggi kalium serta tinggi vitamin C. Kata kunci: Albedo Semangka, Kulit Buah Naga, Selai Lembaran, Hipertensi, Zat Gizi, Aktivitas Antioksida

Effectiveness of Topical Cyclosporin-A 0.1% Compared to Combined Topical Cyclosporin-A 0.1% with Topical Sodium Hyaluronate on Interleukin-6 Levels in the Tears of Patients with Dry Eye Disease

Introduction: Pro-inflammatory cytokines are important contributors to dry eye disease (DED). The cytokine interleukin (IL)-6 has become a therapeutic target in several DED drug studies. This randomized controlled trial aimed to determine the effectiveness of topical cyclosporin-A 0.1% compared to the combination of topical cyclosporin-A 0.1% and sodium hyaluronate in reducing tear IL-6 levels in DED patients. Methods: The participants were 20 patients, each with two eyes, who had moderate-to-severe DED. Before and after treatment, the clinical degree of DED was examined in each group, using ocular surface disease index (OSDI) scores, tear break-up time (TBUT), fluorescent tests, and Schirmer I tests. In addition, tear samples were taken to examine IL-6 levels through the ELISA method. The results were analyzed using the t-test, Wilcoxon test, and Mann–Whitney test. The correlation between tear IL-6 levels and the severity of DED was analyzed using the Spearman correlation test. Results: The study showed a significantly lower tear IL-6 level, OSDI score, and degree of ocular staining after either topical cyclosporin-A 0.1% or a combination of topical cyclosporin-A 0.1% and sodium hyaluronate (all values p < 0.05). Conclusions: The combination therapy was superior in reducing tear IL-6 levels. In addition, a correlation existed between tear IL-6 levels and the severity of DED based on the TBUT, although it was weak and not statistically significant

The Effectiveness of Android-based Education Media of Growth and Development Care Towards Mother's Knowledge Improvement

A Finnish study aimed to see the effect of using android-based educational media for child development care (Pekka Madising) on increasing mother's knowledge. The study is a quasi-experimental study with one control group and one control pretest-posttest group. Each group was given educational media in the form of Pekka madising application in the intervention group and Printed Out in the cont print drop for a week. The results showed that there were differences in the level of knowledge of respondents before being given the intervention, namely (p-Value = 0.736) at and after being given it