Effect of therapeutic dose X rays on mechanical and chemical properties of esthetic dental materials

The aim of this study was to investigate the influence of therapeutic dose X rays on the microhardness (MH) and degree of conversion (DC) of two different esthetic restorative dental materials. The materials were photo-activated with a LED light-curing unit using three cure-times: 5, 20 and 40 seconds. The photo-activation was carried out in two distinct periods: before and after irradiation with doses of 5, 35 and 70 Gy, from a 6 MV X rays beam. In accordance with the methodology used, it was conclude that a therapeutic dose does not have a detrimental effect on the photoinitiator molecules, because the photo-activation occurred after they were irradiated. When the irradiation was applied before photo-activation, the materials showed MH improvement, but when photo-activation was performed after irradiation, there was less improvement. However, there was no correlation between MH and DC. Thus, a therapeutic dose applied to cured material can promote linking and breaking of chain bonds in a non-linear way.FUNCAM

Correlation between Porcine and Human Skin Models by Optical Methods

Background: Topical photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA) and methyl aminolevulinate (MAL) as precursors of protoporphyrin IX (PPIX) have been used in skin cancer treatment and other skin diseases. To establish new topical PDT, protocols are necessary first to conduct studies in vivo using animal skin models. The goal of this study is to evaluate the robust correlation between porcine and human skin models in vivo by optical methods to confirm the suitability of porcine skin models to predict drug behavior in the human skin on topical PDT protocols. Methods: The study was performed in vivo using porcine and human skin models. In human skin, ALA and MAL cream mixture samples were applied to the inner arm in a circular area of 1 cm2. In porcine skin, the cream was applied on the back in an area of 4 cm2, over which an occlusive dressing was placed. PPIX production was monitored for up to 5 h using widefield fluorescence imaging and fluorescence spectroscopy techniques. Results: Human skin models showed similar behavior to porcine skin models, which indicates high similarity between both models and confirms that porcine skin is an adequate model to establish new clinical PDT protocols in human volunteers

Effect of therapeutic dose X rays on mechanical and chemical properties of esthetic dental materials

The aim of this study was to investigate the influence of therapeutic dose X rays on the microhardness (MH) and degree of conversion (DC) of two different esthetic restorative dental materials. The materials were photo-activated with a LED light-curing unit using three cure-times: 5, 20 and 40 seconds. The photo-activation was carried out in two distinct periods: before and after irradiation with doses of 5, 35 and 70 Gy, from a 6 MV X rays beam. In accordance with the methodology used, it was conclude that a therapeutic dose does not have a detrimental effect on the photoinitiator molecules, because the photo-activation occurred after they were irradiated. When the irradiation was applied before photo-activation, the materials showed MH improvement, but when photo-activation was performed after irradiation, there was less improvement. However, there was no correlation between MH and DC. Thus, a therapeutic dose applied to cured material can promote linking and breaking of chain bonds in a non-linear way.113313318FUNCAM

Effect of Four Bleaching Regimens on Color Changes and Microhardness of Dental Nanofilled Composite

Objective. The purpose of this study was to compare the color changes and microhardness of a nanocomposite after four bleaching regimens. Materials. Twenty-five specimens (n = 25) were made with a nanocomposite resin (Filtek Supreme XT). The specimens were divided into five groups equally (n = 5): bleaching groups and control group, as follows: G1: artificial saliva at 37°C; (control) G2: hydrogen peroxide (HP) at 7%; G3: hydrogen peroxide (HP) at 35%; G4: carbamide peroxide (CP) at 10%; G5: carbamide peroxide (CP) 35%. Color measurements were made with spectrophotometer using CIELAB color scale. The Vickers hardness (VHN) measurements were performed at the top surface. The data were analyzed with two-way Analysis of Variance. Results. ΔE and VHN mean values into the groups were not statistically different, however, the VHN mean values before and after storage and bleaching showed statistically significant differences. Conclusion. Nanocomposite samples showed no significant alteration (color and microhardness) after bleaching. Thus, no replacement of restorations is required after bleaching

Continuously assessing and improving software quality with software analytics tools: a case study

In the last decade, modern data analytics technologies have enabled the creation of software analytics tools offering real-time visualization of various aspects related to software development and usage. These tools seem to be particularly attractive for companies doing agile software development. However, the information provided by the available tools is neither aggregated nor connected to higher quality goals. At the same time, assessing and improving software quality has also been a key target for the software engineering community, yielding several proposals for standards and software quality models. Integrating such quality models into software analytics tools could close the gap by providing the connection to higher quality goals. This study aims at understanding whether the integration of quality models into software analytics tools provides understandable, reliable, useful, and relevant information at the right level of detail about the quality of a process or product, and whether practitioners intend to use it. Over the course of more than one year, the four companies involved in this case study deployed such a tool to assess and improve software quality in several projects. We used standardized measurement instruments to elicit the perception of 22 practitioners regarding their use of the tool. We complemented the findings with debriefing sessions held at the companies. In addition, we discussed challenges and lessons learned with four practitioners leading the use of the tool. Quantitative and qualitative analyses provided positive results; i.e., the practitioners’ perception with regard to the tool’s understandability, reliability, usefulness, and relevance was positive. Individual statements support the statistical findings and constructive feedback can be used for future improvements. We conclude that potential for future adoption of quality models within software analytics tools definitely exists and encourage other practitioners to use the presented seven challenges and seven lessons learned and adopt them in their companies.Peer ReviewedPostprint (published version