599 research outputs found

    EFFECT OF LIBRARY SERVICES ON STUDENTS’ ACADEMIC ACHIEVEMENT IN SECONDARY SCHOOL AT BANKURA DISTRICT IN WEST BENGAL

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    A library can be defined as a location where information materials in various formats are methodically gathered, arranged, kept, maintained, and made available to users when necessary to suit their information needs. This study's purpose is to examine how library services affect students' academic performance in secondary schools in West Bengal's Bankura. Researcher used survey method and descriptive statistics for conducting this research work. Researcher find out and conclude that is significant difference between library service and academic achievement of secondary level students Ho1 in Bankura District and Ho2 is finding that negative relationship observed between library service and academic achievement of secondary level of students

    Appendicular endometriosis: a case report

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    Endometriosis is an estrogen-dependent inflammatory disease that affects 8 to 10% of women at reproductive age, characterized by the presence of endometrial glands and stroma outside the uterine cavity. In our case we are presenting a case report of a reproductive age group woman with appendicular endometriosis, because of the presence of pelvic endometriosis combined with an enlarged appendix, the choice was appendectomy, with complete suppression of abdominal symptoms after the surgery, a fact also reported by other authors. We concluded that endometriosis of the appendix is rare and almost never diagnosed before the surgery, with the definitive diagnosis obtained through microscopic examination. However, it should always be taken into account for the diagnosis of chronic pelvic pain, especially in young women complaining of recurrent pain, history of infertility and pelvic endometriosis.

    Az érett T-sejtes lymphomák funkcionális patogenezise = Functional pathogenesis of mature T-cell lymphomas

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    A világon az elsők között állapítottuk meg, hogy az angioimmunoblastos T-sejtes lymphoma daganatsejtjei az aktivált follicularis B helper T-sejtek (TFH) immunfenotípusát mutatják. A Würzburgi Egyetem Patológiai Intézetével közösen végzett kutatásaink során megállapítottuk egyes perifériás T-sejtes lymphoma entitások funkcionális differenciálódási státuszát. Megállapítottuk, hogy a hepatosplenicus gamma/delta T-sejtes lymphoma hátterében nemcsak 7-es izokromoszóma állhat, hanem az ezzel ekvivalens genetikai eltérést képviselő 7-es ring kromoszóma is. Megállapítottuk, hogy az NFATc1 transzkripciós faktor expresszió epigenetikusan gátolt anaplasiás nagysejtes lymphomában, és ez a gátlás az ezen lymphomákra jellemző immunreceptor jelátvitel károsodására vezethető vissza. Eredményeket értünk el a regulátoros T-sejtek lymphomáinak meghatározása területén is. Meghatároztunk olyan lymphomákat, amelyek a természetes T regulátoros sejtek fenotípusát hordozzák; ilyen lymphomákat még nem írtak le a magyar populációban. Egy jelentős, és relatíve egységes lymphoma csoportot különítettünk el, amelyre a TH3 fenotípus a jellemző. A regulátoros T-sejtekkel kapcsolatos eredményeinket jelenleg foglaljuk össze. Az eddig elért eredményeink nemcsak egyes lymphomák jobb megértését, hanem egyes, eddig alig ismert funkcionális T-sejt szubpopulációk megismerését is szolgálhatják. | We are among hte first investigators who have established that tumor cells of angioimmunoblastic T-cell lymphoma possess the phenotype of activated follicular B helper T-cells (TFH). In collaboration with the Department of Pathology, Wurzburg University, Germany, we have described the functinonal differentiation status of the different nodal peripheral T-cell lymphoma entities. We have described that, besides the 7 isochromosome, its equivalent genetic abrerration, the 7-ring chromosome can also be presented in hepatosplenic gamma/delta T-cell lymphoma. We have described that the NFATc1 transcription factor expression is epigenetically supressed in anaplastic large cell lymphoma, and this suppression is based on impared immunoreceptor signaling, characteristic for anaplastic large cell lymphoma. We achieved substantial result in the definition of regulatory T-cell lymphomas as well. We have described lymphomas showing natural T-regulatory cell phenotype, first in the Hungarian population. We have differentiated an important and relatively homogenous group of lymphomas, which is charcterised by TH3 phenotype. Our results on regulatory T-cells are just being compiled. Our results can facilitate the better understanding of different mature T-cell lympoma enitities, and may contribute to explore immunological properties of some functional T-cell subpopulations
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