Neutron and muon-induced background studies for the AMoRE double-beta decay experiment

AMoRE (Advanced Mo-based Rare process Experiment) is an experiment to search a neutrinoless double-beta decay of $^{100}$Mo in molybdate crystals. The neutron and muon-induced backgrounds are crucial to obtain the zero-background level (<$10^{-5}$ counts/(keV$\cdot$kg$\cdot$yr)) for the AMoRE-II experiment, which is the second phase of the AMoRE project, planned to run at YEMI underground laboratory. To evaluate the effects of neutron and muon-induced backgrounds, we performed Geant4 Monte Carlo simulations and studied a shielding strategy for the AMORE-II experiment. Neutron-induced backgrounds were also included in the study. In this paper, we estimated the background level in the presence of possible shielding structures, which meet the background requirement for the AMoRE-II experiment

Effects of adsorbed phase on diffusion of subcritical hydrocarbons in activated carbon at low pressures

Diffusions of free and adsorbed molecules of subcritical hydrocarbons in activated carbon were investigated to study the influence of adsorbed molecules on both diffusion processes at low pressures. A collision reflection factor, defined as the fraction of molecules undergoing collision to the solid surface over reflection from the surface, is incorporated into Knudsen diffusivity and surface diffusivity in meso/macropores. Since the porous structure of activated carbon is bimodal in nature, the diffusion of adsorbed molecules is contributed by that of weakly adsorbed molecules on the meso/macropore surfaces and that of strongly adsorbed molecules in the small confinement of micropores. The mobility of adsorbed molecules on the meso/macropore surface is characterized by the surface diffusivity D-mu 2, while that in the micropore is characterized by D-mu 1. In our study with subcritical hydrocarbons, we have found that the former increases almost linearly with pressure, while the latter exhibits a sharp increase at a very low-pressure region and then decreases beyond a critical pressure. This critical pressure is identified as a pressure at which the micropores are saturated

Measurement and models accounting for cell death capture hidden variation in compound response.

Cancer cell sensitivity or resistance is almost universally quantified through a direct or surrogate measure of cell number. However, compound responses can occur through many distinct phenotypic outcomes, including changes in cell growth, apoptosis, and non-apoptotic cell death. These outcomes have divergent effects on the tumor microenvironment, immune response, and resistance mechanisms. Here, we show that quantifying cell viability alone is insufficient to distinguish between these compound responses. Using an alternative assay and drug-response analysis amenable to high-throughput measurement, we find that compounds with identical viability outcomes can have very different effects on cell growth and death. Moreover, additive compound pairs with distinct growth/death effects can appear synergistic when only assessed by viability. Overall, these results demonstrate an approach to incorporating measurements of cell death when characterizing a pharmacologic response

Atomic and nano-scale characterization of a 50-year-old hydrated C3S paste

This paper investigates the atomic and nano-scale structures of a 50-year-old hydrated alite paste. Imaged by TEM, the outer product C-S-H fibers are composed of particles that are 1.5-2 nm thick and several tens of nanometers long. 29Si NMR shows 47.9% Q1 and 52.1% Q2, with a mean SiO4 tetrahedron chain length (MCL) of 4.18, indicating a limited degree of polymerization after 50 years' hydration. A Scanning Transmission X-ray Microscopy (STXM) study was conducted on this late-age paste and a 1.5 year old hydrated C3S solution. Near Edge X-ray Absorption Fine Structure (NEXAFS) at Ca L3,2-edge indicates that Ca2 + in C-S-H is in an irregular symmetric coordination, which agrees more with the atomic structure of tobermorite than that of jennite. At Si K-edge, multi-scattering phenomenon is sensitive to the degree of polymerization, which has the potential to unveil the structure of the SiO44 - tetrahedron chain

Adhesion Induced DNA Naturation

DNA adsorption and naturation is modeled via two interacting flexible homopolymers coupled to a solid surface. DNA denatures if the entropy gain for unbinding the two strands overcomes the loss of binding energy. When adsorbed to a surface, the entropy gain is smaller than in the bulk, leading to a stronger binding and, upon neglecting self-avoidance, absence of a denatured phase. Now consider conditions where the binding potentials are too weak for naturation, and the surface potential too weak to adsorb single strands. In a variational approach it is shown that their combined action may lead to a naturated adsorbed phase. Conditions for the absence of naturation and adsorption are derived too. The phase diagram is constructed qualitatively.Comment: 4 pages, 1 figur

Room temperature spin coherence in ZnO

Time-resolved optical techniques are used to explore electron spin dynamics in bulk and epilayer samples of n-type ZnO as a function of temperature and magnetic field. The bulk sample yields a spin coherence time T2* of 20 ns at T = 30 K. Epilayer samples, grown by pulsed laser deposition, show a maximum T2* of 2 ns at T = 10 K, with spin precession persisting up to T = 280 K.Comment: 3 pages, 3 figure

The experience of watching baseball games in Korea: an analysis of user-generated content on social media using Leximancer

The current study explores international tourists’ experiences of watching professional baseball games in Korea. Total 152 reviews posted by tourists on TripAdvisor were analyzed through Leximancer, a computer program used in the qualitative content analysis. The software identified three dominant themes of tourist experiences: the distinctive atmosphere of Korean professional baseball games, the diverse services in the stadium, and fanatical cheering behavior for the team. Moreover, it revealed that international tourists were generally positive toward the culturally distinctive style of Korean professional baseball games. This study suggests that the professional sports of a travel destination can be a form of providing international tourists with pleasurable experiences and a way to learn about the distinctive Korean baseball culture

Immunocytochemical localization of casein kinase II during interphase and mitosis

We have developed specific antibodies to synthetic peptide antigens that react with the individual subunits of casein kinase II (CKII). Using these antibodies, we studied the localization of CKII in asynchronous HeLa cells by immunofluorescence and immunoelectron microscopy. Further studies were done on HeLa cells arrested at the G1/S transition by hydroxyurea treatment. Our results indicate that the CKII alpha and beta subunits are localized in the cytoplasm during interphase and are distributed throughout the cell during mitosis. Further electron microscopic investigation revealed that CKII alpha subunit is associated with spindle fibers during metaphase and anaphase. In contrast, the CKII alpha' subunit is localized in the nucleus during G1 and in the cytoplasm during S. Taken together, our results suggest that CKII may play significant roles in cell division control by shifting its localization between the cytoplasm and nucleus

High Energy Physics from High Performance Computing

We discuss Quantum Chromodynamics calculations using the lattice regulator. The theory of the strong force is a cornerstone of the Standard Model of particle physics. We present USQCD collaboration results obtained on Argonne National Lab's Intrepid supercomputer that deepen our understanding of these fundamental theories of Nature and provide critical support to frontier particle physics experiments and phenomenology.Comment: Proceedings of invited plenary talk given at SciDAC 2009, San Diego, June 14-18, 2009, on behalf of the USQCD collaboratio