3,191 research outputs found

    The Massachusetts Commonwealth Health Insurance Connector: Structure and Functions

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    Describes the role and financing of the Commonwealth Health Insurance Connector Authority, an agency created to help small businesses and individuals buy affordable, high-quality insurance. Considers its potential as a model for national reform

    Adolescent Perceptions of Nutrition: Identifying Memorable Messages

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    Research is necessary to uncover ways to improve adolescent nutrition and reduce obesity rates, particularly in the Appalachian region, which has high rates of food insecurity and adolescent obesity. The current study examines rural cultural norms about food, memorable messages adolescents received about nutrition, and the sources of identified memorable messages. Adolescents shared memorable messages during comprehensive, semi-structured, small group interviews in which participants revealed their individual experiences. Thematic framework analysis is used to present the range and nature of memorable messages about nutrition and to develop strategies for future health campaigns and interventions. This qualitative method of sequential inductive analysis provides transparency of data and resulting interpretations through thematic identification and indexing. Analysis revealed themes of messages that featured critical pieces of the rule-structure of memorable messages – specifically, adherence and consequence regarding nutritional behaviors. Prominent memorable messages of adherence included topics of balance (e.g., MyPlate), type (e.g., junk food), and timing (e.g., “don’t eat after 7 p.m.”). Messages with elements of consequence included communication of short-term (e.g., “breakfast gets your blood flowing) and long-term consequence (e.g., obesity, etc.). Adolescents identified family members, educators, and media as salient sources of memorable messages

    Youth smoking and anti-smoking policies in North Dakota: a system dynamics simulation study

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    Background: The current study utilizes system dynamics to model the determinants of youth smoking and simulate effects of anti-smoking policies in the context of North Dakota, a state with one of the lowest cigarette tax rates in the USA. Methods: An explanatory model was built to replicate historical trends in the youth smoking rate. Three different policies were simulated: 1) an increase in cigarette excise taxes; 2) increased funding for CDC-recommended comprehensive tobacco control programs; and 3) enforcement of increased retailer compliance with age restrictions on cigarette sales. Results: The explanatory model successfully replicated historical trends in adolescent smoking behavior in North Dakota from 1992 to 2014. The policy model showed that increasing taxes to $2.20 per pack starting in 2015 was the most effective of the three policies, producing a 32.6% reduction in youth smoking rate by 2032. Other policies reduced smoking by a much lesser degree (7.0 and 3.2% for comprehensive tobacco control program funding and retailer compliance, respectively). The effects of each policy were additive. Conclusions: System dynamics modeling suggests that increasing cigarette excise taxes are particularly effective at reducing adolescent smoking rates. More generally, system dynamics offers an important complement to conventional analysis of observational data.publishedVersio

    Nickel-Catalyzed Enantioconvergent Borylation of Racemic Secondary Benzylic Electrophiles

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    Nickel‐catalyzed cross‐coupling has emerged as the most versatile approach to date for achieving enantioconvergent carbon–carbon bond formation using racemic alkyl halides as electrophiles. In contrast, there have not yet been reports of the application of chiral nickel catalysts to the corresponding reactions with heteroatom nucleophiles to produce carbon–heteroatom bonds with good enantioselectivity. Herein, we establish that a chiral nickel/pybox catalyst can borylate racemic secondary benzylic chlorides to provide enantioenriched benzylic boronic esters, a highly useful family of compounds in organic synthesis. The method displays good functional group compatibility (e.g., being unimpeded by the presence of an indole, a ketone, a tertiary amine, or an unactivated alkyl bromide), and both of the catalyst components (NiCl_2⋅glyme and the pybox ligand) are commercially available
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