Salmonellosis in Lagos, Nigeria: Incidence of Plasmodium falciparum-associated Co-infection, Patterns of Antimicrobial Resistance, and Emergence of Reduced Susceptibility to Fluoroquinolones

The present study was undertaken to examine the status of antimicrobial resistance in Salmonella-associated diseases, by verifying possible emergence of reduced susceptibility to fluoroquinolones in Salmonella isolates and determining the incidence of Plasmodium falciparum-associated co-infection with Salmonella serotypes. Antimicrobial resistance in clinical isolates of Salmonellae was examined for a 12-month period. Four hundred and forty-one patients comprising two groups were recruited. Group A comprised 235 patients diagnosed by clinicians of having pyrexia, and group B included stool samples of 206 patients presenting with gastroenteritis. Samples were cultured and isolates identified, and drug susceptibility testing was performed using the standard methods. Of the 235 samples screened in group A, 42 Salmonella isolates and 107 Plasmodium spp. were identified. Of the 42 Salmonella isolates, 19 (45.2%) were Salmonella Typhi, 9 (21.4%) S. Enteritidis, and 7 (16.7%) each of S. Paratyphi and S. Arizonae. Plasmodium spp.-associated co-infection with Salmonellae was observed in 16 patients mostly in complicated typhoidal cases and S. Enteritidis-associated bacteraemia. Fiftty-three of the 206 stool samples from group B patients were confirmed positive for bacterial pathogens, made up of 35 Salmonella and 18 Shigella isolates. Of the Salmonella isolates, 18 (51.4%) were S. Enteritidis, 11 (31.4%) S. Arizonae, 4 (11.4%) S. Paratyphi, and 2 (5.7%) S. Typhi. There was no statistically significant difference (p<0.01) in antimicrobial resistance patterns exhibited among typhoidal Salmonellae isolated in 2000 and 2005. A similar trend in resistance was recorded for non-typhoidal Salmonellae (p<0.05). For the first time in Lagos, Nigeria, Salmonella isolates (10–18%) with reduced susceptibility to both ciprofloxacin and ofloxacin at MIC50 and MIC90 values of 0.015 and 0.03 μg/mL respectively were found. Despite this development, ciprofloxacin and ofloxacin remain the drug of choice for severe cases of salmonellosis, although caution should be exercised by clinicians in their pres-criptions such that fluoroquinolone antibiotic therapy is used only in laboratory-proven cases of typhoid fever and Salmonella-associated bacteraemia to preserve its efficacy

Overcoming Language Barriers in Business-To-Consumer Electronic Service

Communication has been described as one of the determinants of service quality. However, communication is only effective when the parties involved speak the same language. This is almost impossible to achieve in Business-To-Consumer (B2C) Electronic Commerce (e-Commerce) given the diversity of languages used on the Internet. This paper seeks to explore the possibility of using current advances in technology to bridge the communication gap among entities on the Internet

Salmonellosis in Lagos, Nigeria: Incidence of Plasmodium falciparum -associated Co-infection, Patterns of Antimicrobial Resistance, and Emergence of Reduced Susceptibility to Fluoroquinolones

The present study was undertaken to examine the status of antimicrobial resistance in Salmonella-associated diseases, by verifying possible emergence of reduced susceptibility to fluoroquinolones in Salmonella isolates and determining the incidence of Plasmodium falciparum -associated co-infection with Salmonella serotypes. Antimicrobial resistance in clinical isolates of Salmonellae was examined for a 12-month period. Four hundred and forty-one patients comprising two groups were recruited. Group A comprised 235 patients diagnosed by clinicians of having pyrexia, and group B included stool samples of 206 patients presenting with gastroenteritis. Samples were cultured and isolates identified, and drug susceptibility testing was performed using the standard methods. Of the 235 samples screened in group A, 42 Salmonella isolates and 107 Plasmodium spp. were identified. Of the 42 Salmonella isolates, 19 (45.2%) were Salmonella Typhi, 9 (21.4%) S. Enteritidis, and 7 (16.7%) each of S. Paratyphi and S. Arizonae. Plasmodium spp.-associated co-infection with Salmonellae was observed in 16 patients mostly in complicated typhoidal cases and S. Enteritidis-associated bacteraemia. Fiftty-three of the 206 stool samples from group B patients were confirmed positive for bacterial pathogens, made up of 35 Salmonella and 18 Shigella isolates. Of the Salmonella isolates, 18 (51.4%) were S. Enteritidis, 11 (31.4%) S. Arizonae, 4 (11.4%) S. Paratyphi, and 2 (5.7%) S. Typhi. There was no statistically significant difference (p&lt;0.01) in antimicrobial resistance patterns exhibited among typhoidal Salmonellae isolated in 2000 and 2005. A similar trend in resistance was recorded for non-typhoidal Salmonellae (p&lt;0.05). For the first time in Lagos, Nigeria, Salmonella isolates (10-18%) with reduced susceptibility to both ciprofloxacin and ofloxacin at MIC50 and MIC90 values of 0.015 and 0.03 \ub5g/mL respectively were found. Despite this development, ciprofloxacin and ofloxacin remain the drug of choice for severe cases of salmonellosis, although caution should be exercised by clinicians in their prescriptions such that fluoroquinolone antibiotic therapy is used only in laboratory-proven cases of typhoid fever and Salmonella-associated bacteraemia to preserve its efficacy

INFLUENCE OF BOTANICALS ON SOIL FERTILITY POTENTIALS, SEED GERMINATION AND PERFORMANCE OF MAIZE (ZEA MAYS) VARIETIES UNDER LOW FERTILE CONTINUOUSLY-CROPPED SOIL CONDITIONS

It is not unreasonable to state that, even before the introduction of organic agriculture, African local farmers have numerous of undocumented environment-friendly, nature-inclined indigenous techniques for boosting soil fertility and enhancing crop yield. However, despite the versatility of indigenous knowledge, setback is always experienced from western science, which tags such knowledge as being non-scientific and not worthy of scholarly engagements. A field experiment was carried out in the year 2013, at the Teaching and Research Farms, Ladoke Akintola University of Technology, Ogbomoso, to assess the soil fertility and yield promoting potentials of some indigenous plant species’ botanicals used as pre-planting treatments on different maize varieties. It was a 3 by 5 factorial experiment. The treatments introduced were: Three (3) maize varieties (V1 = ACR-DMR-SR-Y, V2 = Local EM-W and V3 = Suwan Solo Yellow and five (5) other treatments (comprising pre-sowing botanical treatments of: Kigelia africana only, Glyphea brevis only, combination of Kigelia africana and Glyphea brevis only, NPK fertilizer application (as a reference) and the control (treated with ordinary water only). The trial was laid out in Split Plot in Randomized Complete Block Design (RCBD), replicated three times. Data were collected on growth and yield parameters, and the data collected were analysed using analysis of variance (ANOVA). Means were compared using Duncan Multiple Range Test (DMRT). All the botanical treatments significantly influenced germination, growth, yield and nutrient uptakes of maize, compared to the control. Either of the botanicals tested (with ordinary basal manure application of the pre-existing plant residues on the field), competed effectively with NPK fertilized plants. Hence, since maize responded better to sole treatments of either Kigelia africana or Glyphea brevis extracts, irrespective of varieties than the combined treatment of the two botanicals, any of the maize varieties is therefore recommended as being suitably compatible with either of the sole botanical treatments, in the study area. Thus, this research is reasonable, particularly in the aspects of fertilizer economy, environment-friendliness, organic farming and more profitable crop production in the tropics, where soils are continuously cropped and marginal

The Relevance of Financial Inclusion on Sustainable Economic Growth in Sub-Saharan African Nations

The primary concern of this examination is to systematically survey the importance of inclusive access to finance on the growth in terms of the economy in 48 sub-Saharan African (SSA) sovereign states with periodicity from 1995 to 2017. This study reports the results using both static and dynamic estimation techniques. For consistency, the baseline finding of the study estimation is based on the Generalized Method of Moments (GMM) system GMM. This article finds that there is a complimentary association between the present degree of inclusiveness of finance and economic advancement in SSA. The suggestion deduced in this examination is that programs with the plan of comprehensive financing ought to be custom fitted to the agricultural segment of the economy to encourage more economic opportunities for development in a sustainable manne

Comparative Analysis of Upstream Petroleum Fiscal Systems of Three (3) Petroleum Exporting Countries: Indonesia, Nigeria and Malaysia

The role of oil: its output and infrastructure and technology in the world are established. Exploration and Exploitation of oil is not only significant as a revenue generator but has become indispensible in the world economy especially as a result of the inability of world economy to find a better substitute. The recent decline and fluctuation arising from oil sector over the decades have prompted a reassessment of petroleum fiscal systems. The research compares the current upstream fiscal systems of three oil exporting countries: Nigeria, Indonesia and Malaysia. The approach adopted for this study is a review of the existing literature on fiscal regimes; the focus is an objective presentation of empirical evidence. The methodology involved desktop research which looked into published literature. Based on the evaluation, the paper arrived at possible conclusions and implications for oil fiscal regimes for the respective countries and the world fiscal systems in general