656 research outputs found

    Geometric and structural design of foldable structures

    Full text link
    p. 2392-2404This paper initially investigates the previous works on foldable structures. Subsequently, generation and geometric (architectural) design of compatible foldable structures with scissor-like elements is formulated for various shapes of barrels with no geometric limitations (free forms) for the purpose of configuration processing. Special cases for configuration processing based on given formulation are studied to obtain different geometries. For example, the division of the sum of the internal angles of duplets leads to different geometries. The method employed for this division could be equal between duplets, according to arithmetic or geometric progression, or using algebraic equations. These methods are used to divide the sum of internal angles and radius of curvature; Corresponding geometries are then created and compared. The method to generate a geometry imposed by architectural requirements is also proposed in this work. Using such ordering, one can create and model free form foldable structures. To provide changeability for geometry of the structure, a special mid-connection (pivot) is proposed and a prototype model is constructed to demonstrate the efficiency. To construct real scale foldable structures, some connections and a simple method to analyze and design of this type of connections are proposed. A graph of maximum displacement vs. height of the structure is illustrated. A design-construct methodology for foldable structures is proposed.Babaei, M.; Sanaei, E. (2010). Geometric and structural design of foldable structures. Editorial Universitat Politècnica de València. http://hdl.handle.net/10251/728

    Isolation, spectroscopic characterization, X-ray, theoretical studies as well as in vitro cytotoxicity of Samarcandin

    Get PDF
    Samarcandin 1, a natural sesquiterpene-coumarin, was isolated as well as elucidated from F. assa-foetida which has significant effect in Iranian traditional medicine because of its medicinal attitudes. The crystal structure of samarcandin was determined by single-crystal X-ray structure analysis. It is orthorhombic, with unit cell parameters a = 10.8204 (5) Å, b = 12.9894 (7) Å, c = 15.2467 (9) Å, V = 2142.9 (2) Å3, space group P212121 and four symmetry equivalent molecules in the unit cell. Samarcandin was isolated in order to study for its theoretical studies as well as its cellular toxicity as anti-cancer drug against two cancerous cells. In comparison with controls, our microscopic and MTT assay data showed that samarcandin suppresses cancer cell proliferation in a dose-dependent manner with IC50 = 11 μM and 13 for AGS and WEHI-164 cell lines, respectively. Density functional theory (DFT) and time-dependent density functional theory (TD-DFT) of the structure was computed by three functional methods and 6-311++G∗∗ standard basis set. The optimized molecular geometry and theoretical analysis agree closely to that obtained from the single crystal X-ray crystallography. To sum up, the good correlations between experimental and theoretical studies by UV, NMR, and IR spectra were found. © 2016 Elsevier Inc. All rights reserved

    Molecular and morphological characterization of the tapeworm Taenia hydatigena (Pallas, 1766) in sheep from Iran

    Get PDF
    Although Taenia hydatigena is one of the most prevalent taeniid species of livestock, very little molecular genetic information exists for this parasite. Up to 100 sheep isolates of T. hydatigena were collected from 19 abattoirs located in the provinces of Tehran, Alborz and Kerman. A calibrated microscope was used to measure the larval rostellar hook lengths. Following DNA extraction, fragments of cytochrome c oxidase 1 (CO1) and 12S rRNA genes were amplified by the polymerase chain reaction method and the amplicons were subjected to sequencing. The mean total length of large and small hooks was 203.4 μm and 135.9 μm, respectively. Forty CO1 and 39 12S rRNA sequence haplotypes were obtained in the study. The levels of pairwise nucleotide variation between individual haplotypes of CO1 and 12S rRNA genes were determined to be between 0.3-3.4% and 0.2-2.1%, respectively. The overall nucleotide variation among all the CO1 haplotypes was 9.7%, and for all the 12S rRNA haplotypes it was 10.1%. A significant difference was observed between rostellar hook morphometry and both CO1 and 12S rRNA sequence variability. A significantly high level of genetic variation was observed in the present study. The results showed that the 12S rRNA gene is more variable than CO1. © 2013 Cambridge University Press

    Shape from Release: Inverse Design and Fabrication of Controlled Release Structures

    Get PDF

    H-GA-PSO Method for Tuning of a PID Controller for a Buck-Boost Converter Modeled with a New Method of Signal Flow Graph Technique

    Full text link
    In this paper, a new method of signal flow graph technique and Mason's gain formula are applied for extracting the model and transfer functions from control to output and from input to output of a buck-boost converter. In order to investigate necessity of a controller for the converter with assumed parameters, the frequency and time domain analysis is done and the open loop system characteristics are verified. In addition, the needed closed loop controlled system specifications are determined. Moreover, designing a controller for the mentioned converter system based on the extracted model is discussed. For this purpose, a proportional-integral-derivative (PID) controller is designed and the hybrid of genetic algorithm (GA) and particle swarm optimization (PSO), called H-GA-PSO method is used for tuning of the PID controller. Finally, the simulation results are used to show the performance of the proposed modeling and regulation methods

    The Influence of GPL Reinforcements on the Post-Buckling Behavior of FG Porous Rings Subjected to an External Pressure

    Get PDF
    The work focuses on the post- buckling behavior of functionally graded graphene platelet (FG-GPL)-reinforced porous thick rings with open-cell internal cavities under a uniform external pressure. The generalized rule of mixture and the modified Halpin–Tsai model are here used to evaluate the effective mechanical properties of the ring. Three types of porosity patterns are assumed together with five different GPL distributions as reinforcement across the ring thickness. The theoretical formulation relies on a 2D-plane stress linear elasticity theory and Green strain field in conjunction a virtual work principle to derive the nonlinear governing equations of the postbuckling problem. Unlike the simple ring models, 2D elasticity considers the thickness stretching. The finite element model combined with an iterative Newton–Raphson algorithm is used to obtain the post-buckling path of the ring up to the collapse. A systematic investigation evaluates the effect of the weight fraction of nanofillers, the coefficient of porosity, porosity distribution, and the GPLs distribution on the deep post-buckling path of the ring. Based on the results, it is found that the buckling value and post-buckling strength increase considerably (by approximately 80%) by increasing the weight fraction of the nanofiller of about 1%

    Combined Economic Dispatch and Reliability in Power System by Using PSO-SIF Algorithm

    Get PDF
    Reliability investigation has always been one of the most important issues in power systems planning. The outages rate in power system reflects the fact that more attentions should be paid on reliability indices to supply consumers with uninterrupted power. Using reliability indices in economic dispatch problem may lead to the system load demand with high reliability and low probability of power's outage rate. In this paper, the Economic Dispatch (ED) problem is optimized using the reliability indices. That is, ED problem and system reliability are proposed as Combined Economic Dispatch and Reliability (CEDR) problem. In CEDR problem, it is tried to utilize generating units in a way that we have high reliability in supplying the system load demand as well as the minimum fuel costs. Due to multi-objective and non-convex characteristics of this problem, Particle Swarm Optimization with Smart Inertia Factor (PSO-SIF) is used to solve the problem. In this research, the ED of power plants is successfully implemented in two systems with 6 and 26 generating units considering emission and system reliability

    Bioactivation of 3D Cell-Imprinted Polydimethylsiloxane Surfaces by Bone Protein Nanocoating for Bone Tissue Engineering

    Get PDF
    Physical and chemical parameters that mimic the physiological niche of the human body have an influence on stem cell fate by creating directional signals to cells. Micro/nano cell-patterned polydimethylsiloxane (PDMS) substrates, due to their ability to mimic the physiological niche, have been widely used in surface modification. Integration of other factors such as the biochemical coating on the surface can achieve more similar microenvironmental conditions and promote stem cell differentiation to the target cell line. Herein, we investigated the effect of physical topography, chemical functionalization by acid bone lysate (ABL) nanocoating, and the combined functionalization of the bone proteins' nanocoated surface and the topographically modified surface. We prepared four distinguishing surfaces: plain PDMS, physically modified PDMS by 3D cell topography patterning, chemically modified PDMS with bone protein nanocoating, and chemically modified nano 3D cell-imprinted PDMS by bone proteins (ABL). Characterization of extracted ABL was carried out by Bradford staining and sodium dodecyl sulfate polyacrylamide gel electrophoresis analysis, followed by the MTT assay for evaluation of cell viability on ABL-coated PDMS. Moreover, field emission scanning electron microscopy and profilometry were used for the determination of optimal coating thickness, and the appropriate coating concentration was identified and used in the study. The binding and retention of ABL to PDMS were confirmed by Fourier transform infrared spectroscopy and bicinchoninic acid assay. Sessile drop static water contact angle measurements on substrates showed that the combined chemical functionalization and nano 3D cell-imprinting on the PDMS surface improved surface wettability by 66% compared to plain PDMS. The results of ALP measurement, alizarin red S staining, immunofluorescence staining, and real-time PCR showed that the nano 3D cell-imprinted PDMS surface functionalized by extracted bone proteins, ABL, is able to guide the fate of adipose derived stem cellss toward osteogenic differentiation. Eventually, chemical modification of the cell-imprinted PDMS substrate by bone protein extraction not only improved the cell adhesion and proliferation but also contributed to the topographical effect itself and caused a significant synergistic influence on the process of osteogenic differentiation
    • …
    corecore