Work-related musculoskeletal disorders in anesthesiologists: A cross-sectional study on prevalence and risk factors

Aim: To investigate the prevalence of self-reported work-related musculoskeletal disorders (WRMDs) of anesthesiologists, to evaluate potential risk factors, including personal and workload characteristics and working ergonomics. Material and Methods: A cross-sectional international survey including personal and workload characteristics of anesthesiologists was conducted. The Standardized Nordic Musculoskeletal Questionnaire was used to identify working ergonomics and the quality of ergonomic conditions of the operating room. The prevalence of WRMDs was calculated, and predictors of these symptoms were evaluated using binary logistic regression. Results: 98.4% of respondents reported a WRMD in the previous 12 months, mainly low back disorders (70.7%). Cardiothoracic anesthesiologists were more likely to report 12-month knee problems (66%). Overall, pediatric anesthesiologists were more likely to report 12-month WRMDs in most of their body sites. Women were more likely to develop WRMDs in the upper back (OR=2.465; 95% CI:1.061-5.729) as compared with men. Long-duration bending was the most significant ergonomic hazard for all 3 body regions of musculoskeletal symptoms, with an OR of 4.210 (95% CI:1.081-16.391) for the neck, 4.619 (1.274-16.744) for the upper back, and 4.750 (1.045-21.590) for the low back. Suboptimal quality of ergonomic conditions in the operating room was significantly associated with increased WRMDs risk of the neck (OR=0.346; 95% CI:0.147- 0.812) and shoulder (OR=0.405; 95% CI:0.167- 0.982) regions. Conclusion: Anesthesiologists are at high risk for WRMDs. There is a need to improve ergonomic conditions of operative rooms according to demands of anesthesiologists and to educate them on proper posture for a longer and pain-free career

Reinterpreting American missionary presence in the Ottoman Empire : American schools and the evolution of Ottoman educational policies (1820-1908)

Ankara : Institute of Economics and Social Sciences of Bilkent University, 1997.Thesis (Master's) -- Bilkent University, 1997.Includes bibliographical references leaves 105-112An interesling aspect of Ottoman educational modernization in the nineteenth century was its relation to the boom in the number of foreign schools in the 1-mpire. This period witnessed the development of an educational web by American missionaries, in a very rapid and comprehensive manner compared to the development of other foreign schools in the same dominions. This development did not escape the attention of Ottoman rulers and bureaucrats, and there were significant efforts to provide for a regular inspection of these schools. The purpose of this study is to trace the evolution of Ottoman educational policies and their utilization with regard to the American schools in the limpire.Başaran, BetülM.S

Recent Advances in Health Biotechnology During Pandemic

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in 2019, cut the epoch that will make profound fluctuates in the history of the world in social, economic, and scientific fields. Urgent needs in public health have brought with them innovative approaches, including diagnosis, prevention, and treatment. To exceed the coronavirus disease 2019 (COVID-19) pandemic, various scientific authorities in the world have procreated advances in real time polymerase chain reaction (RT-PCR) based diagnostic tests, rapid diagnostic kits, the development of vaccines for immunization, and the purposing pharmaceuticals for treatment. Diagnosis, treatment, and immunization approaches put for- ward by scientific communities are cross-fed from the accrued knowledge of multidisciplinary sciences in health biotechnology. So much so that the pandemic, urgently prioritized in the world, is not only viral infections but also has been the pulsion in the development of novel approaches in many fields such as diagnosis, treatment, translational medicine, virology, mi- crobiology, immunology, functional nano- and bio-materials, bioinformatics, molecular biol- ogy, genetics, tissue engineering, biomedical devices, and artificial intelligence technologies. In this review, the effects of the COVID-19 pandemic on the development of various scientific areas of health biotechnology are discussed

The frequency of Duchenne muscular dystrophy/Becker muscular dystrophy and Pompe disease in children with isolated transaminase elevation: results from the observational VICTORIA study

IntroductionElevated transaminases and/or creatine phosphokinase can indicate underlying muscle disease. Therefore, this study aims to determine the frequency of Duchenne muscular dystrophy/Becker muscular dystrophy (DMD/BMD) in male children and Pompe disease (PD) in male and female children with isolated hypertransaminasemia.MethodsThis multi-center, prospective study enrolled patients aged 3–216 months with serum alanine transaminase (ALT) and/or aspartate transaminase (AST) levels >2× the upper limit of normal (ULN) for ≥3 months. Patients with a known history of liver or muscle disease or physical examination findings suggestive of liver disease were excluded. Patients were screened for creatinine phosphokinase (CPK) levels, and molecular genetic tests for DMD/BMD in male patients and enzyme analysis for PD in male and female patients with elevated CPK levels were performed. Genetic analyses confirmed PD. Demographic, clinical, and laboratory characteristics of the patients were analyzed.ResultsOverall, 589 patients [66.8% male, mean age of 63.4 months (standard deviation: 60.5)] were included. In total, 251 patients (188 male and 63 female) had CPK levels above the ULN. Of the patients assessed, 47% (85/182) of male patients were diagnosed with DMD/BMD and 1% (3/228) of male and female patients were diagnosed with PD. The median ALT, AST, and CPK levels were statistically significantly higher, and the questioned neurological symptoms and previously unnoticed examination findings were more common in DMD/BMD patients than those without DMD/BMD or PD (p < 0.001).DiscussionQuestioning neurological symptoms, conducting a complete physical examination, and testing for CPK levels in patients with isolated hypertransaminasemia will prevent costly and time-consuming investigations for liver diseases and will lead to the diagnosis of occult neuromuscular diseases. Trial RegistrationClinicaltrials.gov NCT04120168

Relatório de estágio em farmácia comunitária

Relatório de estágio realizado no âmbito do Mestrado Integrado em Ciências Farmacêuticas, apresentado à Faculdade de Farmácia da Universidade de Coimbr

Personal protective equipment penetration performance may be affected by temperature and humidity

To the Editor, We read with interest the recent article by Wild et al. on the importance of wearing higher protection level gowns during aerosol-generating procedures.1 Their simulation study was mainly based on the penetration of contrast medium diluted with water through different types of gowns. Nevertheless, it has been shown that different ambient, body, and test fluid temperatures and also different types of test fluid may affect the penetration process.2 Moreover, wearing personal protective equipment (PPE) might pose a thermoregulation risk to the practitioner by increasing core body temperature

Puede haber un sesgo de interpretación con respecto al proceso de colocación y retirada

WOS:000658185800016PubMed ID33867188We read with interest the article by Kozanhan et al. showing YouTube might be used for learning donning and doffing of personal protective equipment (PPE) for health care worker

Assessing the educational value and content of YouTube videos for ultrasound-guided subclavian vein catheterization

PubMed ID 37464777Background: The European Society of Anaesthesiology (ESA) published a guideline regarding continuous ultrasound guidance for central venous catheters in 2020. YouTube has been a popular educational platform since its inception. The purpose of the present study was to evaluate the adequacy of videos on ultrasound-guided subclavian vein catheterization posted on YouTube based on this guideline. Method: YouTube was scanned using the keywords associated with ultrasound-guided subclavian vein catheterization and 46 of the 106 most-watched videos were included in the study. The videos were divided into three groups, as individual, manufacturer, and academic according to their sources, and were evaluated as poor, satisfactory, and good in terms of the overall content. The videos were then evaluated based on ESA’s six-title guide for more specific informational content. Results: A total of 46 videos were reviewed and 52.2% (n = 24) were found to be prepared by individuals. Among the videos, the rate of videos describing only venipuncture (poor) was 23.9% (n = 11), 73.9% (n = 34) of videos described the verification of the guidewire location with venipuncture, and 2.2% of videos described all the recommendations suggested by the guide (n = 1). At the end of the catheterization procedure, 4.3% (n = 2) stated that the catheter location should be confirmed by using ultrasound, 15.2% (n = 7) recommended chest-X-ray, and 80.4% (n = 37) did not suggest any. Conclusion: Manufacturer and academic videos can be watched due to their high-quality scores, but it may be practical to prepare training videos with guidelines both for educators and students to have global access to the renewed guideline information

Cefepime-induced encephalopathy in a COVID-19 patient: a case report Response

WOS:000788980400002We thank to Yuan et al. [1] for their comments on our recent publication [2]. First, A priori power analysis was performed for the ANOVA test to demonstrate the primary outcome of our research. A pilot study was conducted to determine the efect size value, and the NRS Group ACB score was 4.58, the Group iPACK + ACB score was 3.41, and the Group PAI+ACB score was 4.22. Standard deviations were homogeneous and the mean was 1.52. Cohen’s efect size was calculated as 0.32 using group means and standard deviation values. Then, as a result of the power analysis performed to reach 80% power with a 5% error (95% confdence level), it was decided to include a total of 99 patients, with a minimum of 33 in each group. To compensate for possible problems, it was decided to collect 5% additional data and reach a total of 105 cases

Reporting drying temperature and humidity may give more standardised results

WOS:000652752100023PubMed ID: 33736914We read with interest the recent article about the simulation studyby Taylor et al.1that showed a high incidence of chlorhexidine trans-fer from skin to gloves, and also from gloves to another surface.Although the simulation study was well designed to demonstrate theseprimary and secondary aims, the actual drying process depends onboth the temperature of volunteers and the environment, and alsothe humidity of the environment.2Taylor et al. did not mention thevolunteer or environmental temperature and humidity. Since adecrease in temperature or high humidity may delay the drying pro-cess, the transfer of chlorhexidine would be affected by these factors.We believe that the addition of environmental factors and patientcharacteristics to similar simulation-based or clinical studies wouldgain more detailed information about this important subje