Economic evaluation of a community based exercise programme to prevent falls

OBJECTIVE: To assess the incremental costs and cost effectiveness of implementing a home based muscle strengthening and balance retraining programme that reduced falls and injuries in older women. DESIGN: An economic evaluation carried out within a randomised controlled trial with two years of follow up. Participants were individually prescribed an exercise programme (exercise group, n=116) or received usual care and social visits (control group, n=117). SETTING: 17 general practices in Dunedin, New Zealand. PARTICIPANTS: Women aged 80 years and older living in the community and invited by their general practitioner to take part. MAIN OUTCOME MEASURES: Number of falls and injuries related to falls, costs of implementing the intervention, healthcare service costs resulting from falls and total healthcare service costs during the trial. Cost effectiveness was measured as the incremental cost of implementing the exercise programme per fall event prevented. MAIN RESULTS: 27% of total hospital costs during the trial were related to falls. However, there were no significant differences in health service costs between the two groups. Implementing the exercise programme for one and two years respectively cost $314 and$265 (1995 New Zealand dollars) per fall prevented, and $457 and$426 per fall resulting in a moderate or serious injury prevented. CONCLUSIONS: The costs resulting from falls make up a substantial proportion of the hospital costs for older people. Despite a reduction in falls as a result of this home exercise programme there was no significant reduction in healthcare costs. However, the results reported will provide information on the cost effectiveness of the programme for those making decisions on falls prevention strategies

The Proper Motion of PSR J0205+6449 in 3C 58

We report on sensitive phase-referenced and gated 1.4-GHz VLBI radio observations of the pulsar PSR J0205+6449 in the young pulsar-wind nebula 3C 58, made in 2007 and 2010. We employed a novel technique where the ~105-m Green Bank telescope is used simultaneously to obtain single-dish data used to determine the pulsar's period as well as to obtain the VLBI data, allowing the VLBI correlation to be gated synchronously with the pulse to increase the signal-to-noise. The high timing noise of this young pulsar precludes the determination of the proper motion from the pulsar timing. We derive the position of the pulsar accurate at the milliarcsecond level, which is consistent with a re-determined position from the Chandra X-ray observations. We reject the original tentative optical identification of the pulsar by Shearer and Neustroev (2008), but rather identify a different optical counterpart on their images, with R-band magnitude ~24. We also determine an accurate proper motion for PSR J0205+6449 of (2.3 +- 0.3) mas/yr, corresponding to a projected velocity of only (35 +- 6) km/s for a distance of 3.2 kpc, at p.a. -38 deg. This projected velocity is quite low compared to the velocity dispersion of known pulsars of ~200 km/s. Our measured proper motion does not suggest any particular kinematic age for the pulsar.Comment: 10 pages, 7 figures; accepted for publication in MNRA

Full spin switch effect for the superconducting current in a superconductor/ferromagnet thin film heterostructure

Superconductor/ferromagnet (S/F) proximity effect theory predicts that the superconducting critical temperature of the F1/F2/S or F1/S/F2 trilayers for the parallel orientation of the F1 and F2 magnetizations is smaller than for the antiparallel one. This suggests a possibility of a controlled switching between the superconducting and normal states in the S layer. Here, using the spin switch design F1/F2/S theoretically proposed by Oh et al. [Appl. Phys. Lett. 71, 2376 (1997)], that comprises a ferromagnetic bilayer separated by a non-magnetic metallic spacer layer as a ferromagnetic component, and an ordinary superconductor as the second interface component, we have successfully realized a full spin switch effect for the superconducting current.Comment: 5 pages, 4 figure

Variable Depth Bragg Peak Method for Single Event Effects Testing

Traditionally, accelerator SEE testing is accomplished by removing the tops of packages so that the IC chips are accessible to heavy ions. However, ICs in some advanced packages cannot be de-lidded so a different approach is used that involves grinding and/or chemically etching away part of the package and the chip from the back side. The parts are then tested from the back side with ions having sufficient range to reach the sensitive volume. More recently, the entire silicon substrate in an SOI/SRAM was removed, making it possible to use low-energy ions with shorter ranges. Where removal of part of the package is not possible, facilities at Michigan State, NASA Space Radiation Laboratory, GANIL (France) and GSI (Germany) offer high-energy heavy ions with long ranges so that the ions can reach the devices' sensitive volumes without much change in the LET. Unfortunately, a run will typically involve only one ion species having a single energy and LET due to the long time it takes to tune a new energy. The Variable Depth Bragg Peak (VDBP) method is similar to the above method in that it involves the use of high-energy heavy ions that are able to pass through the packaging material and reach the device, obviating the need to remove the package. However, the method provides a broad range of LETs from a single ion by inserting degraders in the beam that modify the ion energy and, therefore, the LET. The crux of the method involves establishing a fiduciary point for degrader thickness, i.e., where the Bragg peak is located precisely at the sensitive volume in the device, for which the measured SEU cross-section and the ion LET are both also maxima and can be calculated using a Monte-Carlo program, TRIM. Once the fiduciary point has been established, calibrated high density polyethylene (HDPE) degraders are inserted into or removed from the beam to vary the ion LET at the device in a known manner. After each change of degrader thickness, the SEU cross-section is measured and the corresponding LET calculated from the change in degrader thickness. That information is used to generate a plot of cross-section as a function of ion LET. The advantages of this approach are that the part does not have to be de-lidded and a broad range of LETs is available from a single heavy ion without having to go to non-normal angles of incidence to change the "effective" LET. As we will show, it is possible to obtain an entire curve of cross-section versus LET using just two or three ions. Fig. 1 shows curves of cross-section vs LET for a Freescale 4 Mbit SOI/SRAM measured at the 88" Cyclotron at Berkeley and at NSRL. The open symbols are the data obtained from Berkeley for top-side and back-side irradiation. The solid data points are for the data obtained at NSRL using a device for which the package was intact. The data are for Iron and Gold and cover a range of LETs from 4 MeV.cm2/mg to 84 MeV.cm2/mg. The agreement between the data obtained from Berkeley and from NSRL is excellent, demonstrating that the VDBP method is capable of providing accurate values of cross-section versus LET, at least for the 4 Mbit SRAM. Details of the technique will be included in the final presentation

The Effect of Coherent Structures on Stochastic Acceleration in MHD Turbulence

We investigate the influence of coherent structures on particle acceleration in the strongly turbulent solar corona. By randomizing the Fourier phases of a pseudo-spectral simulation of isotropic MHD turbulence (Re $\sim 300$), and tracing collisionless test protons in both the exact-MHD and phase-randomized fields, it is found that the phase correlations enhance the acceleration efficiency during the first adiabatic stage of the acceleration process. The underlying physical mechanism is identified as the dynamical MHD alignment of the magnetic field with the electric current, which favours parallel (resistive) electric fields responsible for initial injection. Conversely, the alignment of the magnetic field with the bulk velocity weakens the acceleration by convective electric fields - \bfu \times \bfb at a non-adiabatic stage of the acceleration process. We point out that non-physical parallel electric fields in random-phase turbulence proxies lead to artificial acceleration, and that the dynamical MHD alignment can be taken into account on the level of the joint two-point function of the magnetic and electric fields, and is therefore amenable to Fokker-Planck descriptions of stochastic acceleration.Comment: accepted for publication in Ap

X-ray constraints on the fraction of obscured AGN at high accretion luminosities

The wide-area XMM-XXL X-ray survey is used to explore the fraction of obscured AGN at high accretion luminosities, $L_X (\rm 2-10 \, keV) > 10^{44} \, erg \,s ^{-1}$, and out to redshift $z\approx1.5$. The sample covers an area of about $\rm14\,deg^2$ and provides constraints on the space density of powerful AGN over a wide range of neutral hydrogen column densities extending beyond the Compton-thick limit, $\rm N_H\approx10^{24}\,cm^{-2}$. The fraction of obscured Compton-thin ($\rm N_H=10^{22}-10^{24}\,cm^{-2}$) AGN is estimated to be $\approx0.35$ for luminosities $L_X(\rm 2-10\,keV)>10^{44}\,erg\,s^{-1}$ independent of redshift. For less luminous sources the fraction of obscured Compton-thin AGN increases from $0.45\pm0.10$ at $z=0.25$ to $0.75\pm0.05$ at $z=1.25$. Studies that select AGN in the infrared via template fits to the observed Spectral Energy Distribution of extragalactic sources estimate space densities at high accretion luminosities consistent with the XMM-XXL constraints. There is no evidence for a large population of AGN (e.g. heavily obscured) identified in the infrared and missed at X-ray wavelengths. We further explore the mid-infrared colours of XMM-XXL AGN as a function of accretion luminosity, column density and redshift. The fraction of XMM-XXL sources that lie within the mid-infrared colour wedges defined in the literature to select AGN is primarily a function of redshift. This fraction increases from about 20-30% at z=0.25 to about 50-70% at $z=1.5$.Comment: MNRAS accepte

The X-ray luminosity function of Active Galactic Nuclei in the redshift interval z=3-5

We combine deep X-ray survey data from the Chandra observatory and the wide-area/shallow XMM-XXL field to estimate the AGN X-ray luminosity function in the redshift range z=3-5. The sample consists of nearly 340 sources with either photometric (212) or spectroscopic (128) redshift in the above range. The combination of deep and shallow survey fields provides a luminosity baseline of three orders of magnitude, Lx(2-10keV)~1e43-1e46erg/s at z>3. We follow a Bayesian approach to determine the binned AGN space density and explore their evolution in a model-independent way. Our methodology accounts for Poisson errors in the determination of X-ray fluxes and uncertainties in photometric redshift estimates. We demonstrate that the latter is essential for unbiased measurement of space densities. We find that the AGN X-ray luminosity function evolves strongly between the redshift intervals z=3-4 and z=4-5. There is also suggestive evidence that the amplitude of this evolution is luminosity dependent. The space density of AGN with Lx<1e45erg/s drops by a factor of 5 between the redshift intervals above, while the evolution of brighter AGN appears to be milder. Comparison of our X-ray luminosity function with that of UV/optical selected QSOs at similar redshifts shows broad agreement at bright luminosities, Lx>1e45erg/s. The faint-end slope of UV/optical luminosity functions however, is steeper than for X-ray selected AGN. This implies that the type-I AGN fraction increases with decreasing luminosity at z>3, opposite to trends established at lower redshift. We also assess the significance of AGN in keeping the hydrogen ionised at high redshift. Our X-ray luminosity function yields ionising photon rate densities that are insufficient to keep the Universe ionised at redshift z>4. A source of uncertainty in this calculation is the escape fraction of UV photons for X-ray selected AGN.Comment: MNRAS accepte

Growing Stronger: Strength Training for Older Adults

In choosing to read this book, you have taken the first step on a journey toward greater strength and vitality. Growing Stronger was written for you—the older adult who wants to grow stronger, healthier, more active, and more independent. You may be inactive or only mildly active at the moment. You may know that regular exercise is important for your health and well-being and want to get started on a program of physical activity. But you may feel that you don’t have the necessary information. Perhaps you are concerned that because of your age or health problems physical activity may not be safe for you. Or perhaps you have had trouble finding or staying with a suitable program. This book gives you a safe, simple, and highly effective exercise program based on the principles of strength training. Studies at laboratories around the world have shown that strength training benefits women and men of all ages and all levels of fitness. According to Physical Activity and Health: A Report of the Surgeon General (1996), experts agree that aerobic activities should be supplemented with strength-developing exercises at least twice per week