120 research outputs found
Path Integral Monte Carlo Approach to the U(1) Lattice Gauge Theory in (2+1) Dimensions
Path Integral Monte Carlo simulations have been performed for U(1) lattice
gauge theory in (2+1) dimensions on anisotropic lattices. We extractthe static
quark potential, the string tension and the low-lying "glueball" spectrum.The
Euclidean string tension and mass gap decrease exponentially at weakcoupling in
excellent agreement with the predictions of Polyakov and G{\" o}pfert and Mack,
but their magnitudes are five times bigger than predicted. Extrapolations are
made to the extreme anisotropic or Hamiltonian limit, and comparisons are made
with previous estimates obtained in the Hamiltonian formulation.Comment: 12 pages, 16 figure
Rectification and Flux Reversals for Vortices Interacting with Triangular Traps
We simulate vortices in superconductors interacting with two-dimensional
arrays of triangular traps. We find that, upon application of an ac drive, a
net dc flow can occur which shows current reversals with increasing ac drive
amplitude for certain vortex densities, in agreement with recent experiments
and theoretical predictions. We identify the vortex dynamics responsible for
the different rectification regimes. We also predict the occurrence of a novel
transverse rectification effect in which a dc flow appears that is transverse
to the direction of the applied ac drive.Comment: 4 pages, 4 postscript figure
Tight-binding parameters for charge transfer along DNA
We systematically examine all the tight-binding parameters pertinent to
charge transfer along DNA. The molecular structure of the four DNA bases
(adenine, thymine, cytosine, and guanine) is investigated by using the linear
combination of atomic orbitals method with a recently introduced
parametrization. The HOMO and LUMO wavefunctions and energies of DNA bases are
discussed and then used for calculating the corresponding wavefunctions of the
two B-DNA base-pairs (adenine-thymine and guanine-cytosine). The obtained HOMO
and LUMO energies of the bases are in good agreement with available
experimental values. Our results are then used for estimating the complete set
of charge transfer parameters between neighboring bases and also between
successive base-pairs, considering all possible combinations between them, for
both electrons and holes. The calculated microscopic quantities can be used in
mesoscopic theoretical models of electron or hole transfer along the DNA double
helix, as they provide the necessary parameters for a tight-binding
phenomenological description based on the molecular overlap. We find that
usually the hopping parameters for holes are higher in magnitude compared to
the ones for electrons, which probably indicates that hole transport along DNA
is more favorable than electron transport. Our findings are also compared with
existing calculations from first principles.Comment: 15 pages, 3 figures, 7 table
Fitting the integrated Spectral Energy Distributions of Galaxies
Fitting the spectral energy distributions (SEDs) of galaxies is an almost
universally used technique that has matured significantly in the last decade.
Model predictions and fitting procedures have improved significantly over this
time, attempting to keep up with the vastly increased volume and quality of
available data. We review here the field of SED fitting, describing the
modelling of ultraviolet to infrared galaxy SEDs, the creation of
multiwavelength data sets, and the methods used to fit model SEDs to observed
galaxy data sets. We touch upon the achievements and challenges in the major
ingredients of SED fitting, with a special emphasis on describing the interplay
between the quality of the available data, the quality of the available models,
and the best fitting technique to use in order to obtain a realistic
measurement as well as realistic uncertainties. We conclude that SED fitting
can be used effectively to derive a range of physical properties of galaxies,
such as redshift, stellar masses, star formation rates, dust masses, and
metallicities, with care taken not to over-interpret the available data. Yet
there still exist many issues such as estimating the age of the oldest stars in
a galaxy, finer details ofdust properties and dust-star geometry, and the
influences of poorly understood, luminous stellar types and phases. The
challenge for the coming years will be to improve both the models and the
observational data sets to resolve these uncertainties. The present review will
be made available on an interactive, moderated web page (sedfitting.org), where
the community can access and change the text. The intention is to expand the
text and keep it up to date over the coming years.Comment: 54 pages, 26 figures, Accepted for publication in Astrophysics &
Space Scienc
Recovering Joys Law as a Function of Solar Cycle, Hemisphere, and Longitude
Bipolar active regions in both hemispheres tend to be tilted with respect to
the East West equator of the Sun in accordance with Joys law that describes the
average tilt angle as a function of latitude. Mt. Wilson observatory data from
1917 to 1985 are used to analyze the active-region tilt angle as a function of
solar cycle, hemisphere, and longitude, in addition to the more common
dependence on latitude. Our main results are as follows: i) We recommend a
revision of Joys law toward a weaker dependence on latitude (slope of 0.13 to
0.26) and without forcing the tilt to zero at the Equator. ii) We determine
that the hemispheric mean tilt value of active regions varies with each solar
cycle, although the noise from a stochastic process dominates and does not
allow for a determination of the slope of Joys law on an 11-year time scale.
iii) The hemispheric difference in mean tilt angles, 1.1 degrees + 0.27, over
Cycles 16 to 21 was significant to a three-sigma level, with average tilt
angles in the northern and southern hemispheres of 4.7 degrees + 0.26 and 3.6
degrees + 0.27 respectively. iv) Area-weighted mean tilt angles normalized by
latitude for Cycles 15 to 21 anticorrelate with cycle strength for the southern
hemisphere and whole-Sun data, confirming previous results by Dasi-Espuig,
Solanki, Krivova, et al. (2010, Astron. Astrophys. 518, A7). The northern
hemispheric mean tilt angles do not show a dependence on cycle strength. vi)
Mean tilt angles do not show a dependence on longitude for any hemisphere or
cycle. In addition, the standard deviation of the mean tilt is 29 to 31 degrees
for all cycles and hemispheres indicating that the scatter is due to the same
consistent process even if the mean tilt angles vary.Comment: 13 pages, 4 figures, 3 table
Effects of sleep deprivation on neural functioning: an integrative review
Sleep deprivation has a broad variety of effects on human performance and neural functioning that manifest themselves at different levels of description. On a macroscopic level, sleep deprivation mainly affects executive functions, especially in novel tasks. Macroscopic and mesoscopic effects of sleep deprivation on brain activity include reduced cortical responsiveness to incoming stimuli, reflecting reduced attention. On a microscopic level, sleep deprivation is associated with increased levels of adenosine, a neuromodulator that has a general inhibitory effect on neural activity. The inhibition of cholinergic nuclei appears particularly relevant, as the associated decrease in cortical acetylcholine seems to cause effects of sleep deprivation on macroscopic brain activity. In general, however, the relationships between the neural effects of sleep deprivation across observation scales are poorly understood and uncovering these relationships should be a primary target in future research
Novel genetic loci associated with hippocampal volume
The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (rg =-0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness
Paediatric and adult congenital cardiology education and training in Europe
Background: Limited data exist on training of European paediatric and adult congenital cardiologists. Methods: A structured and approved questionnaire was circulated to national delegates of Association for European Paediatric and Congenital Cardiology in 33 European countries. Results: Delegates from 30 countries (91%) responded. Paediatric cardiology was not recognised as a distinct speciality by the respective ministry of Health in seven countries (23%). Twenty countries (67%) have formally accredited paediatric cardiology training programmes, seven (23%) have substantial informal (not accredited or certified) training, and three (10%) have very limited or no programme. Twenty-two countries have a curriculum. Twelve countries have a national training director. There was one paediatric cardiology centre per 2.66 million population (range 0.87-9.64 million), one cardiac surgical centre per 4.73 million population (range 1.63-10.72 million), and one training centre per 4.29 million population (range 1.63-10.72 million population). The median number of paediatric cardiology fellows per training programme was 4 (range 1-17), and duration of training was 3 years (range 2-5 years). An exit examination in paediatric cardiology was conducted in 16 countries (53%) and certification provided by 20 countries (67%). Paediatric cardiologist number is affected by gross domestic product (R-2 = 0.41). Conclusion: Training varies markedly across European countries. Although formal fellowship programmes exist in many countries, several countries have informal training or no training. Only a minority of countries provide both exit examination and certification. Harmonisation of training and standardisation of exit examination and certification could reduce variation in training thereby promoting high-quality care by European congenital cardiologists.Developmen
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