613 research outputs found

    Games and Activities for the English as a Second Language Classroom

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    A study has been made to select activities and games that promote language use in the second language classroom. Low classroom and personal anxiety promote language learning; games and activities are a method of focusing the language on its message rather than its structural form. Ways for teachers to help decrease classroom pressure and encourage learning are discussed. Language games for beginning, intermediate, and advanced students are presented in the project portion of this paper and will be used as a handbook of games for English as a second language teachers

    Achieving shared situational awareness during steadystate operations in New York state : a model for success

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    CHDS State/LocalIn order to effectively engage in decision making for the safety and well-being of the citizens of New York, the governor and state leaders must have access to real-time, accurate, and comprehensive information. During response operations, the state emergency operations center serves as the focal point for information exchange. During steady-state operations, gaps exist in information sharing, resulting in a fragmented understanding of the operating environment. This lack of a shared situational awareness during steady-state operations requires public-safety leaders to spend time developing a shared situational awareness when an untoward event emerges. This thesis explores the terms situational awareness, shared situational awareness and common operating picture as they apply during steady-state operations. It argues for the importance of shared situational awareness in support of group decision making during the transition from steady-state to response operations, examines existing models of information sharing, and proposes two new models. The thesis concludes that New York State should leverage its Disaster Preparedness Commission interagency coordination architecture to establish a governing body with responsibility for assessing current practices, identifying gaps, and developing strategies to ensure that an all-hazards public-safety shared situational awareness exists through a daily common operating picture.http://archive.org/details/achievingshareds109455375Deputy Director, New York State Emergency Management Office author (civilian)Approved for public release; distribution is unlimited

    Ion-beam mixing induced by atomic and cluster bombardment in the electronic stopping-power regime

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    Single crystals of magnesium oxide containing nanoprecipitates of sodium were bombarded with swift ions (∼GeV-Pb, U) or cluster beams (∼20 MeV-C60) to study the phase change induced by electronic processes at high stopping power (≳10 keV/nm). The sodium precipitates and the defect creation were characterized by optical absorption and transmission electron microscopy. The ion or cluster bombardment leads to an evolution of the Na precipitate concentration but the size distribution remains unchanged. The decrease in Na metallic concentration is attributed to mixing effects at the interfaces between Na clusters and MgO. In addition, optical-absorption measurements show a broadening of the absorption band associated with electron plasma oscillations in Na clusters. This effect is due to a decrease of the electron mean free path, which could be induced by defect creation in the metal. All these results show an influence of high electronic stopping power in materials known to be very resistant to irradiation with weak ionizing projectiles. The dependence of these effects on electronic stopping power and on various solid-state parameters is discussed

    Food security under high bioenergy demand toward long-term climate goals

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    Bioenergy is expected to play an important role in the achievement of stringent climate-change mitigation targets requiring the application of negative emissions technology. Using a multi-model framework, we assess the effects of high bioenergy demand on global food production, food security, and competition for agricultural land. Various scenarios simulate global bioenergy demands of 100, 200, 300, and 400 exajoules (EJ) by 2100, with and without a carbon price. Six global energy-economy-agriculture models contribute to this study, with different methodologies and technologies used for bioenergy supply and greenhouse-gas mitigation options for agriculture. We find that the large-scale use of bioenergy, if not implemented properly, would raise food prices and increase the number of people at risk of hunger in many areas of the world. For example, an increase in global bioenergy demand from 200 to 300 EJ causes a − 11% to + 40% change in food crop prices and decreases food consumption from − 45 to − 2 kcal person−1 day−1, leading to an additional 0 to 25 million people at risk of hunger compared with the case of no bioenergy demand (90th percentile range across models). This risk does not rule out the intensive use of bioenergy but shows the importance of its careful implementation, potentially including regulations that protect cropland for food production or for the use of bioenergy feedstock on land that is not competitive with food production

    Compound C prevents Hypoxia-Inducible Factor-1α protein stabilization by regulating the cellular oxygen availability via interaction with Mitochondrial Complex I

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    The transcription factor Hypoxia-Inducible Factor-1α is a master regulator of the cellular response to low oxygen concentration. Compound C, an inhibitor of AMP-activated kinase, has been reported to inhibit hypoxia dependent Hypoxia-Inducible Factor-1α activation via a mechanism that is independent of AMP-activated kinase but dependent on its interaction with the mitochondrial electron transport chain. The objective of this study is to characterize the interaction of Compound C with the mitochondrial electron transport chain and to determine the mechanism through which the drug influences the stability of the Hypoxia-Inducible Factor-1α protein

    Biomass residues as twenty-first century bioenergy feedstock—a comparison of eight integrated assessment models

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    In the twenty-first century, modern bioenergy could become one of the largest sources of energy, partially replacing fossil fuels and contributing to climate change mitigation. Agricultural and forestry biomass residues form an inexpensive bioenergy feedstock with low greenhouse gas (GHG) emissions, if harvested sustainably. We analysed quantities of biomass residues supplied for energy and their sensitivities in harmonised bioenergy demand scenarios across eight integrated assessment models (IAMs) and compared them with literature-estimated residue availability. IAM results vary substantially, at both global and regional scales, but suggest that residues could meet 7–50% of bioenergy demand towards 2050, and 2–30% towards 2100, in a scenario with 300 EJ/year of exogenous bioenergy demand towards 2100. When considering mean literature-estimated availability, residues could provide around 55 EJ/year by 2050. Inter-model differences primarily arise from model structure, assumptions, and the representation of agriculture and forestry. Despite these differences, drivers of residues supplied and underlying cost dynamics are largely similar across models. Higher bioenergy demand or biomass prices increase the quantity of residues supplied for energy, though their effects level off as residues become depleted. GHG emission pricing and land protection can increase the costs of using land for lignocellulosic bioenergy crop cultivation, which increases residue use at the expense of lignocellulosic bioenergy crops. In most IAMs and scenarios, supplied residues in 2050 are within literature-estimated residue availability, but outliers and sustainability concerns warrant further exploration. We conclude that residues can cost-competitively play an important role in the twenty-first century bioenergy supply, though uncertainties remain concerning (regional) forestry and agricultural production and resulting residue supply potentials

    Evaluation of PRNP Expression Based on Genotypes and Alleles of Two Indel Loci in the Medulla Oblongata of Japanese Black and Japanese Brown Cattle

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    BACKGROUND: Prion protein (PrP) level plays the central role in bovine spongiform encephalopathy (BSE) susceptibility. Increasing the level of PrP decreases incubation period for this disease. Therefore, studying the expression of the cellular PrP or at least the messenger RNA might be used in selection for preventing the propagation of BSE and other prion diseases. Two insertion/deletion (indel) variations have been tentatively associated with susceptibility/resistance of cattle to classical BSE. METHODOLOGY/PRINCIPAL FINDINGS: We studied the expression of each genotype at the two indel sites in Japanese Black (JB) and Japanese Brown (JBr) cattle breeds by a standard curve method of real-time PCR. Five diplotypes subdivided into two categories were selected from each breed. The two cattle breeds were considered differently. Expression of PRNP was significantly (p<0.0001) greater in the homozygous deletion genotype at the 23-bp locus in JB breed. Compared to the homozygous genotypes, the expression of PRNP was significantly greater in the heterozygous genotype at the 12-bp locus in JB (p<0.0001) and in JBr (p = 0.0394) breeds. In addition, there was a statistical significance in the PRNP levels between the insertion and the deletion alleles of the 23-bp locus in JB (p = 0.0003) as well as in JBr (p = 0.0032). There was no significance in relation to sex, age, geographical location or due to their interactions (p>0.05). CONCLUSION: Our results suggest that the del/del genotype or at least its del allele may modulate the expression of PRNP at the 23-bp locus in the medulla oblongata of these cattle breeds

    Waveguide-integrated silicon T centres

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    The performance of modular, networked quantum technologies will be strongly dependent upon the quality of their quantum light-matter interconnects. Solid-state colour centres, and in particular T centres in silicon, offer competitive technological and commercial advantages as the basis for quantum networking technologies and distributed quantum computing. These newly rediscovered silicon defects offer direct telecommunications-band photonic emission, long-lived electron and nuclear spin qubits, and proven native integration into industry-standard, CMOS-compatible, silicon-on-insulator (SOI) photonic chips at scale. Here we demonstrate further levels of integration by characterizing T centre spin ensembles in single-mode waveguides in SOI. In addition to measuring long spin T_1 times, we report on the integrated centres' optical properties. We find that the narrow homogeneous linewidth of these waveguide-integrated emitters is already sufficiently low to predict the future success of remote spin-entangling protocols with only modest cavity Purcell enhancements. We show that further improvements may still be possible by measuring nearly lifetime-limited homogeneous linewidths in isotopically pure bulk crystals. In each case the measured linewidths are more than an order of magnitude lower than previously reported and further support the view that high-performance, large-scale distributed quantum technologies based upon T centres in silicon may be attainable in the near term
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