Polyphase Glacigenic Deformation of Advance Glaciofluvial Sediments, Near Big Creek, British Colombia

Deformation structures were observed in glaciofluvial sediments near Big Creek, central British Columbia. These sediments record a sequence of polyphase deformation resulting from the advance and retreat of the Late Wisconsinan (Fraser Glaciation) Cordilleran Ice Sheet. Deformation is attributed to ductile then brittle failure resulting from: (a) horizontal compression and loading as ice advanced over saturated sediments; followed by (b) lateral extension then (c) compression under frozen conditions during glacier overriding; and finally (d) vertical extension during unloading upon déglaciation. Most deformation (a-c, above) appears to have occurred during the advance phase of the Fraser Glaciation.Des structures de déformation ont été observées dans des sédiments fluvioglaciaires, près de Big Creek. Ces sédiments comprennent la séquence d'une déformation polyphasée résultant de l'avancée et du retrait de l'Inlandsis de la Cordillère (Glaciation de Fraser) au Wisconsinien supérieur. La déformation est attribuée à des fractures d'abord de type ductile, puis cassant résultant : (a) d'une compression et d'une charge horizontales à mesure que la glace avançait sur les sédiments saturés; suivie (b) d'une extension latérale, puis (c) d'une compression en milieu gelé pendant la phase de chevauchement glaciaire; et enfin (d) d'une extension verticale pendant la décharge au moment de la déglaciation. La plus grande partie de la déformation (a-c) s'est produite au cours de la phase d'avancée de la Glaciation de Fraser.Nahe bei Big Creek im Zentrum von British Columbia hat man Verformungsstrukturen in fluvioglazialen Sedimenten beobachtet. Diese Sedimente belegen eine Sequenz mehrphasiger Verformung, welche durch den VorstoB und Rùckzug der Kordilleren-Eisdecke im spaten Wisconsin (Fraser-Vereisung) verursacht wurde. Die Verformung fuhrt man auf zunàchst geschmeidiges, dann sprodes Nachgeben zuruck, veranlaRt durch: (a) horizontale Verdichtung und Anhâufung wàhrend das Eis uber die saturierten Sedimente vordrang, darauf folgend (b) eine latérale Ausdehnung und dann (c) Verdichtung in vereistem Milieu wàhrend der Gletscherûberschiebung, und schlie&lich (d) vertikale Ausdehnung wàhrend der durch die Enteisung bewirkten Stromungen. Der grôRte TeN der Verformung (siehe a-c oben) scheint wàhrend der VorstoRphase der Fraser-Vereisung geschehen zu sein

Assessing the Impact of Integrated Personal Health and Care Services: the Need for Modelling

In Europe Public expenditure for healthcare and Long-Term Care (LTC) currently absorbs 6.8% of GDP and without innovative cost containment measures could almost double by 2050 and reach 12.8% of GDP due to several socio-economic and cultural trends. This challenge can be turned into an opportunity for inclusive innovation and growth if the potential of ICT would be fully exploited to deliver personal health and social care services to prevent and manage chronic diseases (i.e. remote monitoring and treatment) or to ensure a dignified and independent living at home for the elderly (i.e. Ambient Assisted Living, AAL). This potential is fully recognised in both the EU2020 Strategy and in the new Digital Agenda for Europe, and one of the first European Innovation Partnership in 2011 will focus on Health and Ageing and related services. This favourable context, however, suffers from a scientific gap with important strategic implications for policy making: there exists currently no micro or macro economic empirical or modelling analysis that would enable policy makers to either demonstrate ex post the impact of Health&Care services or to simulate ex ante their potential impacts. Lacking this support it is at times difficult to win traditional resistance to innovation and push full adoption of such services in Europe. This research explored the availability of tools and methods, both for macro- and micro- modelling tools and processes, assessed their implications, challenges and opportunities and reports on its findings. The paper concludes by laying the foundations for proposing a new research plan that would aim at filling the scientific and policy relevant gap by proposing a hands-on modelling exercise to study the impacts in one country for on chronic disease.JRC.DDG.J.4-Information Societ

The Development of Canada's Competency Profile for Professional Geoscientists at Entry-to-Practice

Competency-based assessment approaches to professional registration reflect the move by professions, both in Canada and around the world, away from traditional credentials-based assessments centred on a combination of academic achievements and supervised practice time. Entry to practice competencies are the abilities required to enable effective and safe entry-level practice in a profession.   In 2012, Geoscientists Canada received funding from the Government of Canada’s Foreign Credentials Recognition Program. A central component of the funding involved the development of a competency profile to assist in assessment for licensing in the geoscience profession. Work concluded with the approval of the Competency Profile for Professional Geoscientists at Entry to Practice by Geoscientists Canada in November 2014.   The Competency Profile comprises concise statements in plain language, setting out the skills and abilities that are required to be able to work as a geoscientist, in an effective and safe manner, independent of direct supervision. It covers competencies common to all geoscientists; competencies for the primary subdisciplines of geoscience (geology, environmental geoscience and geophysics); and a generic set of high level competences that can apply in any specific work context in geoscience.   The paper is in two parts. Part 1 puts the concept of competencies in context and describes the approach taken to develop the profile, including: input from Subject Matter Experts (practising geoscientists representing a diverse sampling of the profession); extensive national consultation and refinement; and a validation procedure, including a survey of practising Canadian geoscientists. Part 2 introduces the profile, explains its structure, and provides examples of some of the competencies. The full competency profile can be obtained from the Geoscientists Canada website www.geoscientistscanada.ca.  Future work will identify specific indicators of proficiency related to each competency and suggest appropriate methodologies to assess such competencies. It will also involve mapping the profile to the existing Canadian reference standard, Geoscience Knowledge and Experience Requirements for Professional Registration in Canada.RÉSUMÉLes approches d'évaluation basées sur les compétences en vue de l'inscription professionnelle reflètent l'abandon par les professions, tant au Canada que partout dans le monde, des évaluations classiques basées sur les titres de compétences et axées sur une combinaison de réalisations académiques et de temps de pratique supervisée. Les compétences au niveau débutant sont les capacités requises pour une pratique efficace et en toute sécurité audit niveau dans une profession.   En 2012, Géoscientifiques Canada a reçu un financement du Programme de reconnaissance des titres de compétences étrangers du gouvernement du Canada. Une composante centrale du financement incluait l’élaboration d'un profil des compétences pour faciliter l'évaluation de la délivrance de permis dans la profession de géoscience. Ce travail a été conclu en novembre 2014 avec l'approbation par Géoscientifiques Canada du Profil des compétences pour les géoscientifiques professionnels au niveau débutant.   Le profil des compétences comprend des déclarations concises dans un langage clair, définissant les compétences et les capacités requises pour exercer efficacement, en toute sécurité et indépendamment de toute supervision directe, en tant que géoscientifique. Il couvre les compétences communes à tous les géoscientifiques; les compétences pour les sous-disciplines primaires de la géoscience (géologie, géoscience environnementale et géophysique); et un ensemble générique de compétences de haut niveau pouvant s'appliquer dans tout contexte de travail spécifique en géoscience.   Le document comporte deux parties. La 1ère partie met en contexte le concept de compétences et décrit l'approche adoptée pour élaborer le profil, y compris : les contributions d'experts dans le domaine (géoscientifiques professionnels représentant un échantillonnage diversifié de la profession); de vastes consultations et perfectionnements à l'échelle nationale; et une procédure de validation, incluant une enquête auprès des géoscientifiques professionnels canadiens. La 2ème partie présente le profil, explique sa structure et fournit des exemples pour certaines des compétences. Le profil des compétences complet est disponible sur le site web de Géoscientifiques Canada www.geoscientistscanada.ca.   Les travaux futurs identifieront des indicateurs spécifiques d’aptitude liés à chaque compétence et suggèreront des méthodologies appropriées pour leur évaluation. Ils comprendront également la mise en correspondance du profil avec la norme de référence canadienne existante et les exigences en matière de Connaissances et expérience des géosciences requises pour l'inscription à titre professionnel au Canada.

Dynamic software randomisation: Lessons learnec from an aerospace case study

Timing Validation and Verification (V&V) is an important step in real-time system design, in which a system's timing behaviour is assessed via Worst Case Execution Time (WCET) estimation and scheduling analysis. For WCET estimation, measurement-based timing analysis (MBTA) techniques are widely-used and well-established in industrial environments. However, the advent of complex processors makes it more difficult for the user to provide evidence that the software is tested under stress conditions representative of those at system operation. Measurement-Based Probabilistic Timing Analysis (MBPTA) is a variant of MBTA followed by the PROXIMA European Project that facilitates formulating this representativeness argument. MBPTA requires certain properties to be applicable, which can be obtained by selectively injecting randomisation in platform's timing behaviour via hardware or software means. In this paper, we assess the effectiveness of the PROXIMA's dynamic software randomisation (DSR) with a space industrial case study executed on a real unmodified hardware platform and an industrial operating system. We present the challenges faced in its development, in order to achieve MBPTA compliance and the lessons learned from this process. Our results, obtained using a commercial timing analysis tool, indicate that DSR does not impact the average performance of the application, while it enables the use of MBPTA. This results in tighter pWCET estimates compared to current industrial practice.The research leading to these results has received funding from the European Community’s FP7 [FP7/2007-2013] under the PROXIMA Project (www.proxima-project.eu), grant agreement no 611085. This work has also been partially supported by the Spanish Ministry of Science and Innovation under grant TIN2015-65316-P and the HiPEAC Network of Excellence. Jaume Abella has been partially supported by the Ministry of Economy and Competitiveness under Ramon y Cajal postdoctoral fellowship number RYC-2013-14717.Peer ReviewedPostprint (author's final draft

Envisioning Digital Europe 2030: Scenarios for ICT in Future Governance and Policy Modelling

The report Envisioning Digital Europe 2030 is the result of research conducted by the Information Society Unit of IPTS as part of the CROSSROAD Project - A Participative Roadmap on ICT research on Electronic Governance and Policy Modelling (www.crossroad-eu.net ). After outlining the purpose and scope of the report and the methodological approach followed, the report presents the results of a systematic analysis of societal, policy and research trends in the governance and policy modelling domain in Europe. These analyses are considered central for understanding and roadmapping future research on ICT for governance and policy modelling. The study further illustrates the scenario design framework, analysing current and future challenges in ICT for governance and policy modelling, and identifying the key impact dimensions to be considered. It then presents the scenarios developed at the horizon 2030, including the illustrative storyboards representative of each scenario and the prospective opportunities and risks identified for each of them. The scenarios developed are internally consistent views of what the European governance and policy making system could have become by 2030 and of what the resulting implications for citizens, business and public services would be. Finally, the report draws conclusions and presents the proposed shared vision for Digital Europe 2030, offering also a summary of the main elements to be considered as an input for the future development of the research roadmap on ICT for governance and policy modelling.JRC.DDG.J.4-Information Societ

The 2010 Report on R&D in ICT in the European Union

This report is the 2010 edition of a report that is published annually. It presents all the data available on ICT R&D private and public expenditures in Europe, at sector, country and company levels, and from an international perspective (benchmarking). It provides data up to 2007. The second part of the report includes a thematic analysis on ICT R&D internationalisation.JRC.DDG.J.4-Information Societ

Probabilistic timing analysis on time-randomized platforms for the space domain

Timing Verification is a fundamental step in real-time embedded systems, with measurement-based timing analysis (MBTA) being the most common approach used to that end. We present a Space case study on a real platform that has been modified to support a probabilistic variant of MBTA called MBPTA. Our platform provides the properties required by MBPTA with the predicted WCET estimates with MBPTA being competitive to those with current MBTA practice while providing more solid evidence on their correctness for certification.The research leading to these results has received funding from the European Community’s FP7 [FP7/2007-2013] under the PROXIMA Project (www.proxima-project.eu), grant agreement no 611085. This work has also been partially supported by the Spanish Ministry of Science and Innovation under grant TIN2015-65316-P and the HiPEAC Network of Excellence. Jaume Abella has been partially supported by the Ministry of Economy and Competitiveness under Ramon y Cajal postdoctoral fellowship number RYC-2013-14717. Carles Hernandez is jointly funded by the Spanish Ministry of Economy and Competitiveness and FEDER funds through grant TIN2014-60404-JIN.Peer ReviewedPostprint (author's final draft

Functional Human \u3cem\u3eGRIN2B\u3c/em\u3e Promoter Polymorphism and Variation of Mental Processing Speed in Older Adults

We investigated the role of a single nucleotide polymorphism rs3764030 (G \u3e A) within the human GRIN2B promoter in mental processing speed in healthy, cognitively intact, older adults. In vitro DNA-binding and reporter gene assays of different allele combinations in transfected cells showed that the A allele was a gain-of-function variant associated with increasing GRIN2B mRNA levels. We tested the hypothesis that individuals with A allele will have better memory performance (i.e. faster reaction times) in older age. Twenty-eight older adults (ages 65-86) from a well-characterized longitudinal cohort were recruited and performed a modified delayed match-to-sample task. The rs3764030 polymorphism was genotyped and participants were grouped based on the presence of the A allele into GG and AA/AG. Carriers of the A allele maintained their speed of memory retrieval over age compared to GG carriers (p = 0.026 slope of the regression line between AA and AG versus GG groups). To validate the results, 12 older adults from the same cohort participated in a different version of the short-term memory task. Reaction times were significantly slower with age in older adults with G allele (p \u3c 0.001). These findings support a role for rs3764030 in maintaining faster mental processing speed over aging

The Impact of Social Computing on the EU Information Society and Economy

This report provides a systematic empirical assessment of the creation, use and adoption of specific social computing applications and its impact on ICT/media industries, personal identity, social inclusion, education and training, healthcare and public health, and government services and public governance.JRC.J.4-Information Societ

Alzheimer\u27s Biomarkers are Correlated with Brain Connectivity in Older Adults Differentially During Resting and Task States

β-amyloid (Aβ) plaques and tau-related neurodegeneration are pathologic hallmarks of Alzheimer’s disease (AD). The utility of AD biomarkers, including those measured in cerebrospinal fluid (CSF), in predicting future AD risk and cognitive decline is still being refined. Here, we explored potential relationships between functional connectivity (FC) patterns within the default-mode network (DMN), age, CSF biomarkers (Aβ42 and pTau181), and cognitive status in older adults. Multiple measures of FC were explored, including a novel time series-based measure [total interdependence (TI)]. In our sample of 27 cognitively normal older adults, no significant associations were found between levels of Aβ42 or pTau181 and cognitive scores or regional brain volumes. However, we observed several novel relationships between these biomarkers and measures of FC in DMN during both resting-state and a short-term memory task. First, increased connectivity between bilateral anterior middle temporal gyri was associated with higher levels of CSF Aβ42 and Aβ42/pTau181 ratio (reflecting lower AD risk) during both rest and task. Second, increased bilateral parietal connectivity during the short-term memory task, but not during rest, was associated with higher levels of CSF pTau181 (reflecting higher AD risk). Third, increased connectivity between left middle temporal and left parietal cortices during the active task was associated with decreased global cognitive status but not CSF biomarkers. Lastly, we found that our new TI method was more sensitive to the CSF Aβ42-connectivity relationship whereas the traditional cross-correlation method was more sensitive to levels of CSF pTau181 and cognitive status. With further refinement, resting-state connectivity and task-driven connectivity measures hold promise as non-invasive neuroimaging markers of Aβ and pTau burden in cognitively normal older adults