Absolute spacetime: the twentieth century ether

All gauge theories need ``something fixed'' even as ``something changes.'' Underlying the implementation of these ideas all major physical theories make indispensable use of an elaborately designed spacetime model as the ``something fixed,'' i.e., absolute. This model must provide at least the following sequence of structures: point set, topological space, smooth manifold, geometric manifold, base for various bundles. The ``fine structure'' of spacetime inherent in this sequence is of course empirically unobservable directly, certainly when quantum mechanics is taken into account. This issue is at the basis of the difficulties in quantizing general relativity and has been approached in many different ways. Here we review an approach taking into account the non-Boolean properties of quantum logic when forming a spacetime model. Finally, we recall how the fundamental gauge of diffeomorphisms (the issue of general covariance vs coordinate conditions) raised deep conceptual problems for Einstein in his early development of general relativity. This is clearly illustrated in the notorious ``hole'' argument. This scenario, which does not seem to be widely known to practicing relativists, is nevertheless still interesting in terms of its impact for fundamental gauge issues.Comment: Contribution to Proceedings of Mexico Meeting on Gauge Theories of Gravity in honor of Friedrich Heh

Is Quantum Mechanics Compatible with a Deterministic Universe? Two Interpretations of Quantum Probabilities

Two problems will be considered: the question of hidden parameters and the problem of Kolmogorovity of quantum probabilities. Both of them will be analyzed from the point of view of two distinct understandings of quantum mechanical probabilities. Our analysis will be focused, as a particular example, on the Aspect-type EPR experiment. It will be shown that the quantum mechanical probabilities appearing in this experiment can be consistently understood as conditional probabilities without any paradoxical consequences. Therefore, nothing implies in the Aspect experiment that quantum theory is incompatible with a deterministic universe.Comment: REVISED VERSION! ONLY SMALL CHANGES IN THE TEXT! compressed and uuencoded postscript, a uuencoded version of a demo program file (epr.exe for DOS) is attached as a "Figure

Exotic Smoothness and Physics

The essential role played by differentiable structures in physics is reviewed in light of recent mathematical discoveries that topologically trivial space-time models, especially the simplest one, ${\bf R^4}$, possess a rich multiplicity of such structures, no two of which are diffeomorphic to each other and thus to the standard one. This means that physics has available to it a new panoply of structures available for space-time models. These can be thought of as source of new global, but not properly topological, features. This paper reviews some background differential topology together with a discussion of the role which a differentiable structure necessarily plays in the statement of any physical theory, recalling that diffeomorphisms are at the heart of the principle of general relativity. Some of the history of the discovery of exotic, i.e., non-standard, differentiable structures is reviewed. Some new results suggesting the spatial localization of such exotic structures are described and speculations are made on the possible opportunities that such structures present for the further development of physical theories.Comment: 13 pages, LaTe

Localized Exotic Smoothness

Gompf's end-sum techniques are used to establish the existence of an infinity of non-diffeomorphic manifolds, all having the same trivial ${\bf R^4}$ topology, but for which the exotic differentiable structure is confined to a region which is spatially limited. Thus, the smoothness is standard outside of a region which is topologically (but not smoothly) ${\bf B^3}\times {\bf R^1}$, where ${\bf B^3}$ is the compact three ball. The exterior of this region is diffeomorphic to standard ${\bf R^1}\times {\bf S^2}\times{\bf R^1}$. In a space-time diagram, the confined exoticness sweeps out a world tube which, it is conjectured, might act as a source for certain non-standard solutions to the Einstein equations. It is shown that smooth Lorentz signature metrics can be globally continued from ones given on appropriately defined regions, including the exterior (standard) region. Similar constructs are provided for the topology, ${\bf S^2}\times {\bf R^2}$ of the Kruskal form of the Schwarzschild solution. This leads to conjectures on the existence of Einstein metrics which are externally identical to standard black hole ones, but none of which can be globally diffeomorphic to such standard objects. Certain aspects of the Cauchy problem are also discussed in terms of ${\bf R^4_\Theta}$\models which are ``half-standard'', say for all $t<0,$ but for which $t$ cannot be globally smooth.Comment: 8 pages plus 6 figures, available on request, IASSNS-HEP-94/2

The Origin of Structures in Generalized Gravity

In a class of generalized gravity theories with general couplings between the scalar field and the scalar curvature in the Lagrangian, we can describe the quantum generation and the classical evolution of both the scalar and tensor structures in a simple and unified manner. An accelerated expansion phase based on the generalized gravity in the early universe drives microscopic quantum fluctuations inside a causal domain to expand into macroscopic ripples in the spacetime metric on scales larger than the local horizon. Following their generation from quantum fluctuations, the ripples in the metric spend a long period outside the causal domain. During this phase their evolution is characterized by their conserved amplitudes. The evolution of these fluctuations may lead to the observed large scale structures of the universe and anisotropies in the cosmic microwave background radiation.Comment: 5 pages, latex, no figur

Protein-decorated microbubbles for ultrasound-mediated cell surface manipulation

Delivering cargo to the cell membranes of specific cell types in the body is a major challenge for a range of treatments, including immunotherapy. This study investigates employing protein-decorated microbubbles (MBs) and ultrasound (US) to “tag” cellular membranes of interest with a specific protein. Phospholipid-coated MBs were produced and functionalized with a model protein using a metallochelating complex through an NTA(Ni) and histidine residue interaction. Successful “tagging” of the cellular membrane was observed using microscopy in adherent cells and was promoted by US exposure. Further modification of the MB surface to enable selective binding to target cells was then achieved by functionalizing the MBs with a targeting protein (transferrin) that specifically binds to a receptor on the target cell membrane. Attachment and subsequent transfer of material from MBs functionalized with transferrin to the target cells significantly increased, even in the absence of US. This work demonstrates the potential of these MBs as a platform for the noninvasive delivery of proteins to the surface of specific cell types

Black Holes with a Massive Dilaton

The modifications of dilaton black holes which result when the dilaton acquires a mass are investigated. We derive some general constraints on the number of horizons of the black hole and argue that if the product of the black hole charge $Q$ and the dilaton mass $m$ satisfies $Q m < O(1)$ then the black hole has only one horizon. We also argue that for $Q m > O(1)$ there may exist solutions with three horizons and we discuss the causal structure of such solutions. We also investigate the possible structures of extremal solutions and the related problem of two-dimensional dilaton gravity with a massive dilaton.Comment: 36 pages with 5 figures (as uuencoded compressed tar file) (revised version has one major change in bound on mass for extremal solution and minor typos fixed), harvma

Geometrization of the electro-weak model bosonic component

In this work we develop a geometrical unification theory for gravity and the electro-weak model in a Kaluza-Klein approach; in particular, from the curvature dimensional reduction Einstein-Yang-Mills action is obtained. We consider two possible space-time manifolds: 1)$V^{4}\otimes S^{1}\otimes S^{2}$ where isospin doublets are identified with spinors; 2) $V^{4}\otimes S^{1}\otimes S^{3}$ in which both quarks and leptons doublets can be recast into the same spinor, such that the equal number of quark generations and leptonic families is explained. Finally a self-interacting complex scalar field is introduced to reproduce the spontaneous symmetry breaking mechanism; in this respect, at the end we get an Higgs fields whose two components have got opposite hypercharges.Comment: 15 pages, no figures, to appear on Int. Jour. of Theor. Phy

Scalar GW detection with a hollow spherical antenna

We study the response and cross sections for the absorption of GW energy in a Jordan-Brans-Dicke theory by a resonant mass detector shaped as a hollow sphere.Comment: latex file, 9 page

A time-space varying speed of light and the Hubble Law in static Universe

We consider a hypothetical possibility of the variability of light velocity with time and position in space which is derived from two natural postulates. For the consistent consideration of such variability we generalize translational transformations of the Theory of Relativity. The formulae of transformations between two rest observers within one inertial system are obtained. It is shown that equality of velocities of two particles is as relative a statement as simultaneity of two events is. We obtain the expression for the redshift of radiation of a rest source which formally reproduces the Hubble Law. Possible experimental implications of the theory are discussed.Comment: 7 page