Detecting slope and urban potential unstable areas by means of multi-platform remote sensing techniques: the Volterra (Italy) case study

Volterra (Central Italy) is a town of great historical interest, due to its vast and well-preserved cultural heritage, including a 2.6 km long Etruscan-medieval wall enclosure representing one of the most important elements. Volterra is located on a clayey hilltop prone to landsliding, soil erosion, therefore the town is subject to structural deterioration. During 2014, two impressive collapses occurred on the wall enclosure in the southwestern urban sector. Following these events, a monitoring campaign was carried out by means of remote sensing techniques, such as space-borne (PS-InSAR) and ground-based (GB-InSAR) radar interferometry, in order to analyze the displacements occurring both in the urban area and the surrounding slopes, and therefore to detect possible critical sectors with respect to instability phenomena. Infrared thermography (IRT) was also applied with the aim of detecting possible criticalities on the wall-enclosure, with special regards to moisture and seepage areas. PS-InSAR data allowed a stability back-monitoring on the area, revealing 19 active clusters displaying ground velocity higher than 10 mm/year in the period 2011–2015. The GB-InSAR system detected an acceleration up to 1.7 mm/h in near-real time as the March 2014 failure precursor. The IRT technique, employed on a double survey campaign, in both dry and rainy conditions, permitted to acquire 65 thermograms covering 23 sectors of the town wall, highlighting four thermal anomalies. The outcomes of this work demonstrate the usefulness of different remote sensing technologies for deriving information in risk prevention and management, and the importance of choosing the appropriate technology depending on the target, time sampling and investigation scale. In this paper, the use of a multi-platform remote sensing system permitted technical support of the local authorities and conservators, providing a comprehensive overview of the Volterra site, its cultural heritage and landscape, both in near-real time and back-analysis and at different scales of investigation

Typical examples of classical novae

Because of the very complicated individualistic behavior of each nova, we think it necessary to review the observations of a few well-observed individuals. We have selected a few objects of different speed classes, which have been extensively observed. They are: V1500 Cygni 1975, a very fast nova; V603 Aql 1918, fast nova; CP Pup 1942, fast nova; GK Per 1901, fast nova; V 1668 Cyg 1979, moderately fast nova; FH Ser 1970, slow nova; DQ Her 1934, slow nova; T Aur 1891, slow nova; RR Pic 1925, slow nova; and HR Del 1967, very slow nova

Factors associated with walking, moderate and vigorous physical activities in adolescents

This study aimed at investigating the relationship between a set of variables (adolescents' gender, age, economic level, nutritional status, and fathers' educational level) and physical activity practices. The sample consisted of 578 students from a public school, aged between 11 and 16 years. The International Physical Activity Questionnaire (IPAQ, version 8, short form) was applied in order to measure their physical activity practices. Chi-square, independent t test and one-way ANOVA were implemented. Thirteen percent of adolescents were physically inactive and no significant difference was found between gender (p > .05). Compared to boys, girls spent more time in walking (p = .019) and vigorous activities (p = .017). Adolescents aged 14-16 years spent more time in walking compared with those aged 11-12 years (p = .026) and 13-year-olds (p = .006). There was a positive association between economic level and time spent in moderate physical activity (p = .034)

Sorting Nexin 1 Down-Regulation Promotes Colon Tumorigenesis

PURPOSE: Colon cancer is one of the most common human malignancies, yet studies have only begun to identify the multiple mechanisms that underlie the development of this tumor. In this study, we have identified a novel mechanism, dysregulation of endocytic sorting, which promotes colon cancer development. EXPERIMENTAL DESIGN: Immunohistochemical and microarray analyses were done on human colon cancer tissue specimens to determine the levels of one endocytic protein, sorting nexin 1 (SNX1). SW480 cells, a human colon cancer cell line that retains a relatively high level of SNX1 expression, were used to assess the effects of down-regulating this protein by small hairpin RNA. Activation of signal transduction cascades was evaluated in these cells using Western blotting, and multiple functional assays were done. RESULTS: We determined by immunohistochemistry that the level of SNX1 was significantly down-regulated in 75% of human colon cancers. In corroborative studies using microarray analysis, SNX1 message was significantly decreased (log(2) ratio less than -1) for 8 of 19 colon carcinomas. Cell lines with reduced SNX1 levels showed increased proliferation, decreased apoptosis, and decreased susceptibility to anoikis. They also showed increased activation of epidermal growth factor receptor and extracellular signal-regulated kinase 1/2 in response to epidermal growth factor. This increased activation was abolished by inhibition of endocytosis. CONCLUSIONS: These data suggest that loss of SNX1 may play a significant role in the development and aggressiveness of human colon cancer, at least partially through the mechanism of increased signaling from endosomes. Further, these findings suggest that dysregulation of endocytic proteins may represent a new paradigm in the process of carcinogenesis.Fil: Nguyen, Lananh N.. University of Washington; Estados UnidosFil: Holdren, Matthew S.. University of Washington; Estados UnidosFil: Nguyen, Anthony P.. Baylor College of Medicine; Estados UnidosFil: Furuya, Momoko H.. University of Washington; Estados UnidosFil: Bianchini, Michele. Fundación Cáncer. Centro de Investigaciones Oncológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Levy, Estrella Mariel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Cáncer. Centro de Investigaciones Oncológicas; ArgentinaFil: Mordoh, Jose. Fundación Cáncer. Centro de Investigaciones Oncológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Liu, Annie. University of Washington; Estados UnidosFil: Guncay, Gabriela D.. University of Washington; Estados UnidosFil: Campbell, Jean S.. University of Washington; Estados UnidosFil: Parks, W. Tony. University of Washington; Estados Unido

Myers' type theorems and some related oscillation results

In this paper we study the behavior of solutions of a second order differential equation. The existence of a zero and its localization allow us to get some compactness results. In particular we obtain a Myers' type theorem even in the presence of an amount of negative curvature. The technique we use also applies to the study of spectral properties of Schroedinger operators on complete manifolds.Comment: 16 page

A Slope Instability Case History Involving Swelling Clay in Southern Brazil

This paper describes a slope instability case history involving swelling clay. A 9-m high slope was cut in 3 sedimentary layers during the construction of a single-carriage road. A complex slope failure mechanism was identified during site investigation, consisting of: (a) a progressive surficial degradation, particularly of the lower swelling clay layer. (b) a deep-seated slope failure, and (c) the toppling failure of the upper stronger layers. Site investigation included SPT testing, undisturbed sampling and in situ suction measurement. Laboratory testing consisted of: (a) soil characterization by X-ray diffraction analysis, particle-size analysis and Atterberg limits tests; (b) evaluation of effective shear strength parameters using direct shear tests and ring shear tests: and (c) determination of soil-water characteristic curves. Slope stability analyses were carried out followed by comparison with observed field performance

Ultraviolet Emission Line Ratios of Cataclysmic Variables

We present a statistical analysis of the ultraviolet emission lines of cataclysmic variables (CVs) based on $\approx 430$ ultraviolet spectra of 20 sources extracted from the International Ultraviolet Explorer Uniform Low Dispersion Archive. These spectra are used to measure the emission line fluxes of N V, Si IV, C IV, and He II and to construct diagnostic flux ratio diagrams. We investigate the flux ratio parameter space populated by individual CVs and by various CV subclasses (e.g., AM Her stars, DQ Her stars, dwarf novae, nova-like variables). For most systems, these ratios are clustered within a range of $\sim 1$ decade for log Si IV/C IV $\approx -0.5$ and log He II/C IV $\approx -1.0$ and $\sim 1.5$ decades for log N V/C IV $\approx -0.25$. These ratios are compared to photoionization and collisional ionization models to constrain the excitation mechanism and the physical conditions of the line-emitting gas. We find that the collisional models do the poorest job of reproducing the data. The photoionization models reproduce the Si IV/C IV line ratios for some shapes of the ionizing spectrum, but the predicted N V/C IV line ratios are simultaneously too low by typically $\sim 0.5$ decades. Worse, for no parameters are any of the models able to reproduce the observed He II/C IV line ratios; this ratio is far too small in the collisional and scattering models and too large by typically $\sim 0.5$ decades in the photoionization models.Comment: LaTeX format, uses aaspp4.sty, 28 pages, 11 Postscript figures, accepted for publication in The Astrophysical Journal 10/16/9