Crowdsourcing & Marketing: A Relationship in the Making

Crowdsourcing seems to have come of age since Jeff Howe christened it in 2006 and the writing on the wall is clear. As more and more companies are trying to jump on the crowdsourcing bandwagon, crowdsourcing as a marketing strategy is cementing its place in the fiercely competitive business environment and it’s leading the crowd of strategies which have come to the fore in the recent years. The business corridors are buzzing with this ever evolving phenomenon, which no more seems like another buzz word around. As this phenomenon is gaining currency across boundaries, the academic research around this topic has also gained lot of attention. As a result this paper will draw attention toward the marketer’s perspective about crowdsourcing, as they are the one who are the harbinger of the future growth of crowdsourcing. This paper will highlight the level of awareness of crowdsourcing among the marketing managers, their perspective about its use and impact on various marketing strategies. In addition to this, their perspective on digital divide is considered to be discussed, as digital divide could play a spoilsport in the relationship between crowdsourcing and marketing. Most often it is said that if you want to do something different then don’t follow the crowd, first time it seems it is good to follow the crowd

Characterization of High Porous PZT Piezoelectric Ceramics by different Techniques

Ultimate properties of a porous ceramic is highly process dependent. In this study, prevalent porous ceramics fabrication methods (Freeze casting, Foam reticulation and Burnable Plastic Sphere (BURPS) method) have been compared by fabricating the porous lead zirconate titanate (PZT) based piezoelectric ceramics. Field Emission Scanning electron microscopy (FESEM) studies were carried out to study the pore size and distribution of the ceramics. Hydrostatic co-efficients increased tremendously on incorporation of porosity which led to Hydrostatic Figure of Merit of 7480 in Foam reticulation samples (porosity 86%). The three dimensionally interconnected networks in the freeze casted samples led to lowest acoustic impedance (6 MRayls) despite not having the lowest density

Vitamin B12 deficiency in patients of type 2 diabetes mellitus treated with metformin: a cross section observational study from a tertiary care centre in Sub-Himalayan region of North India

Background: Metformin is first line of treatment in type 2 diabetes mellitus (T2DM). It has been reported to be associated with vitamin B12 deficiency with variable results in various studies. The aim of our study is to correlate metformin use and vitamin B12 levels in patients of T2DM with high prevalence in Sub-Himalyan region of north India.Methods: The study was conducted from August 2017 to July 2018 enrolling 124 patients, aged 18 years and above with T2DM taking metformin treatment for >4 months. Vitamin B12 levels were estimated and the levels <200, 200-300 and >300 pg/ml were defined as having definite deficiency, borderline deficiency and normal levels respectively.Results: A total of 124 patients included 66 (53.2%) male and 58 (46.8%) female patients with T2DM on metformin treatment. The mean vitamin B12 level was found significantly low, 176.23±60.96 pg/ml and 18 (14.5%) patients were found to have significant vitamin B12 deficiency and 8(6.5%) patients, borderline deficiency in longer duration of metformin use for >10 years (p<0.001). Vitamin B12 deficiency was found significantly more in 14 (11.3%) patients taking lower doses ≤1000 mg/day of metformin compared to higher doses, a negative correlation. Peripheral neuropathy was significantly present in 15.3% of patients in metformin induced vitamin B12deficiency.Conclusions: Vitamin B12 deficiency was found to be significantly correlated to longer duration of metformin treatment and neuropathy in T2DM but negatively correlated to higher doses of metformin. Therefore, we recommend the assessment and supplementation of vitamin B12 in metformin use in T2DM, compromising financial burden but not the outcome of its deficiency

Computational Study Reliability of Diesel Engine through Electrical Assembly

Consistency of a system is the probability that, under defined operational and environmental conditions, the device can perform a specific function at the end over a specified time [Dinkar et al. 2018]. Reliability must be defined by definitive norm based on many variables, maximum of that may random [Bhardwaj et al. (2018)]. Reliability is arduous to scale, because no such tool is there to do this for specific machine. The reliability of the diverse units of complex machinery depends on their output process, the standard of the composites used in their design, operating conditions, etc. Despite these criteria the reliability of the system is very much related to diverse forms of uncertainty. The numerical assessment of ambiguities is therefore the starting point for a numerical assessment of reliability [Bhardwaj et al. (2019)]. The theory of probability is a concept concerned with the analysis of risk [Li, Y. - F et al. 2006]. Maintenance regulations can address issues pertaining to general maintenance, fix or dump laws, rules on emergency reporting, inventory control, supply of spare parts, etc. Such maintenance policies may be defined in advance and implementation decisions may be taken accordingly. The design process involves unit length assessments, research protocols, degree of automation as well as integrated redundancies, test time, specific test facilities and measures for safety; and so forth [Allan, T.M., 2012]. Performance is an attribute of reliability to reparable systems which accounts for the quality and service property of a component or device. ABC appraisal seeks to distinguish the item from each other and decide the importance of the element and the degree as required by company

A Qualitative Analysis of the Success of Entrepreneurship Development Programs Based on Segment Studies

Entrepreneurship Development Program include Strategies to increase Business which involve identifying areas where new ventures can be set up and so it is important to analyse the success of such program. This Paper is aimed at analysing success of the Entrepreneurship Development Program that are carried out across the country by educational institutions. A Survey was carried out across all such institutes where EDP was delivered and the participants were asked to rate the program attended by them on parameters that play a key role in development of the entrepreneurial skills. The data of 1000 such participants were taken. Their results were segregated and aggregated and the result was studied through pie graphs to give a qualitative analysis of the inclination of each group among the segregated ones

Floristic diversity of Theog Forest Division, Himachal Pradesh, Western Himalaya

We provide a check list of the vascular plants of Theog Forest Division, Himachal Pradesh, Western Himalaya. Himachal Pradesh has been extensively surveyed in terms of flora by a large number of workers, albeit highly confined to prioritized areas. The floristic inventorization resulted in a total of 442 vascular plant species belonging to 311 genera and 117 families from an area of 512 km2. Out of these, 408 species belonged to Angiosperms, 7 to Gymnosperms and 27 to Pteridophytes. The predominant families among Dicotyledons were Asteraceae, Rosaceae and Lamiaceae. Among the Monocotyledons, the most represented family was Poaceae, followed by Liliaceae and Cyperaceae. Pinaceae and Pteridaceae were found to be the most represented families among the Gymnosperms and Pteridophytes, respectively. Species richness was highest in shrubberies, which formed an ideal habitat for many herbaceous species within different habitat types. Strategic eradication of weed species, especially obnoxious species such as Lantana camara and Parthenium hysterophorus is required for effective management in the area

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Not AvailableMaize is a versatile cereal crop having the highest genetic potential, production, and productivity. In the past few decades, plant tissue culture and transformation approaches have played an important role in maize improvement via introducing beneficial transgene(s) or modulating the expression of the endogenous gene(s), etc. However, the capability of in vitro regeneration in maize is highly influenced by genotypes, type of explants, media compositions among others. Some genotypes are more amenable to tissue culture producing embryogenic calli, while others are recalcitrant to tissue culture. Genotypic differences in morphogenesis and organogenesis are generally reported that might be possible due to differences in endogenous hormone levels. The in vitro regeneration potential in maize is usually decreased during the channelized path of tissue maturation, therefore embryogenic callus is mostly achieved from immature zygotic embryos. The present article aimed to provide the current state of the art in maize somatic embryogenesis. Further, the article describes the procedure for maize whole plant regeneration from embryogenic callus.Not Availabl

A Greener Synthesis of 2-Aminochromenes in Ionic Liquid and Evaluation of Their Antiproliferative Activities

An improved simple and facile synthesis of chromene derivatives by employing threecomponent one-pot condensation reaction of β-naphthol, aromatic aldehydes, and malononitrile in ionic liquids is described

Copper Triflate-Mediated Synthesis of 1,3,5-triarylpyrazoles in [bmim][PF6] Ionic Liquid and Evaluation of Their Anticancer Activities

A simple, efficient, and environment friendly protocol for the synthesis of 1,3,5-triarylpyrazoles and 1,3,5-triarylpyrazolines in [bmim][PF6] ionic liquid mediated by Cu(OTf)2 is described. The reaction protocol gave 1,3,5-triarylpyrazoles in good to high yields (71–84%) via a one-pot addition–cyclocondensation between chalcones and arylhydrazines, and oxidative aromatization without the requirement for an additional oxidizing reagent. The catalyst can be reused for up to four cycles without much loss in the catalytic activity. The pyrazoles (4a–o) and pyrazolines (3a–n) were evaluated for their antiproliferative activity in SK-OV-3, HT-29, and HeLa human cancer cells lines. Among all the compounds, 3b inhibited cell proliferation of HeLa cells by 80% at a concentration of 50 μM

Review insights of nanotheranostics for molecular mechanisms underlying psychiatric disorders and commensurate nanotherapeutics for neuropsychiatry: the mind-knockout

© 2021 The Authors. Published by Ivyspring International Publisher. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://dx.doi.org/10.7150%2Fntno.49619Bio-neuronal led psychiatric abnormalities transpired by the loss of neuronal structure and function (neurodegeneration), pro-inflammatory cytokines, microglial dysfunction, altered neurotransmission, toxicants, serotonin deficiency, kynurenine pathway, and excessively produced neurotoxic substances. These uncontrolled happenings in the etiology of psychiatric disorders initiate further changes in neurotransmitter metabolism, pathologic microglial, cell activation, and impaired neuroplasticity. Inflammatory cytokines, the outcome of dysfunctional mitochondria, dysregulation of the immune system, and under stress functions of the brain are leading biochemical factors for depression and anxiety. Nanoscale drug delivery platforms, inexpensive diagnostics using nanomaterials, nano-scale imaging technologies, and ligandconjugated nanocrystals used for elucidating the molecular mechanisms and foremost cellular communications liable for such disorders are highly capable features to study for efficient diagnosis and therapy of the mental illness. These theranostic tools made up of multifunctional nanomaterials have the potential for effective and accurate diagnosis, imaging of psychiatric disorders, and are at the forefront of leading technologies in nanotheranostics openings field as they can collectively and efficiently target the stimulated territories of the cerebellum (cells and tissues) through molecular-scale interactions with higher bioavailability, and bio-accessibility. Specifically, the nanoplatforms based neurological changes are playing a significant role in the diagnosis of psychiatric disorders and portraying the routes of functional restoration of mental disorders by newer imaging tools at nano-level in all directions. Because of these nanotherapeutic platforms, the molecules of nanomedicine can penetrate the Blood-Brain Barrier with an increased half-life of drug molecules. The discoveries in nanotheranostics and nanotherapeutics inbuilt unique multi-functionalities are providing the best multiplicities of novel nanotherapeutic potentialities with no toxicity concerns at the level of nano rangeThe authors thank the National Institute of Medical Sciences, India, for financial support