38 research outputs found
Empirical Tests for Evaluation of Multirate Filter Bank Parameters
Empirical tests have been developed for evaluating the numerical properties of multirate M-band filter banks represented as N matrices of filter coe#cients. Each test returns a numerically observed estimate ofa1 M vector parameter in which the m element corresponds to the m filter band. These vector valued parameters can be readily converted to scalar valued parameters for comparison of filter bank performance or optimization of filter bank design. However, they are intended primarily for the characterization and verification of filter banks. By characterizing the numerical performance of analytic or algorithmic designs, these tests facilitate the experimental verification of theoretical specifications
Comparative assessment of budesonideâMMX and mesalamine in active, mildâtoâmoderate ulcerative colitis: A systematic review and network metaâanalysis
Nutritional management of patients with severe liver disease by using intravenous hyperalimentation and elemental diet
Crossâsectional study on patients' understanding and views of the informed consent procedure of a secondary stroke prevention trial
Background and purpose
Improving understanding of study contents and procedures might enhance recruitment into studies and retention during follow-up. However, data in stroke patients on understanding of the informed consent (IC) procedure are sparse.
Methods
We conducted a cross-sectional study among ischemic stroke patients taking part in the IC procedure of an ongoing cluster-randomized secondary prevention trial. All aspects of the IC procedure were assessed in an interview using a standardized 20-item questionnaire. Responses were collected within 72 h after the IC procedure and analyzed quantitatively and qualitatively. Participants were also asked their main reasons for participation.
Results
A total of 146 stroke patients (65 ± 12 years old, 38% female) were enrolled. On average, patients recalled 66.4% (95% confidence interval = 65.2%â67.5%) of the content of the IC procedure. Most patients understood that participation was voluntary (99.3%) and that they had the right to withdraw consent (97.1%); 79.1% of the patients recalled the study duration and 56.1% the goal. Only 40.3% could clearly state a benefit of participation, and 28.8% knew their group allocation. Younger age, higher graduation, and allocation to the intervention group were associated with better understanding. Of all patients, 53% exclusively stated a personal and 22% an altruistic reason for participation.
Conclusions
Whereas understanding of patient rights was high, many patients were unable to recall other important aspects of study content and procedures. Increased attention to older and less educated patients may help to enhance understanding in this patient population. Actual recruitment and retention benefit of an improved IC procedure remains to be tested in a randomized trial