Sudden Critical Current Drops Induced in S/F Structures

In the search for new physical properties of S/F structures, we have found that the superconductor critical current can be controlled by the domain state of the neighboring ferromagnet. The superconductor is a thin wire of thickness d_{s} ~ 2 xi_{S}. Nb/Co and Nb/Py (Permalloy Ni_{80}Fe_{20}) bilayer structures were grown with a significant magnetic anisotropy. Critical current measurements of Nb/Co structures with ferromagnet thickness d_{F} > 30nm show sudden drops in two very defined steps when the measurements are made along the hard axes direction (i.e. current track parallel to hard anisotropy axes direction). These drops disappear when they are made along the easy axis direction or when the ferromagnet thickness is below 30nm. The drops are accompanied by vortex flux flow. In addition magnetorestistance measurements close to Tc show a sharp increase near saturation fields of the ferromagnet. Similar results are reproduced in Nb/Py bilayer structure with the ferromagnet thickness d_{F} ~ 50nm along the easy anisotropy axes. These results are explained as being due to spontaneous vortex formation and flow induced by Bloch domain walls of the ferromagnet underneath. We argue these Bloch domain walls produce a 2D vortex-antivortex lattice structure.Comment: 6 pages, 6 figure

Negative Specific Heat in a Quasi-2D Generalized Vorticity Model

Negative specific heat is a dramatic phenomenon where processes decrease in temperature when adding energy. It has been observed in gravo-thermal collapse of globular clusters. We now report finding this phenomenon in bundles of nearly parallel, periodic, single-sign generalized vortex filaments in the electron magnetohydrodynamic (EMH) model for the unbounded plane under strong magnetic confinement. We derive the specific heat using a steepest descent method and a mean field property. Our derivations show that as temperature increases, the overall size of the system increases exponentially and the energy drops. The implication of negative specific heat is a runaway reaction, resulting in a collapsing inner core surrounded by an expanding halo of filaments.Comment: 12 pages, 3 figures; updated with revision

Quantum Theory from Quantum Gravity

We provide a mechanism by which, from a background independent model with no quantum mechanics, quantum theory arises in the same limit in which spatial properties appear. Starting with an arbitrary abstract graph as the microscopic model of spacetime, our ansatz is that the microscopic dynamics can be chosen so that 1) the model has a low low energy limit which reproduces the non-relativistic classical dynamics of a system of N particles in flat spacetime, 2) there is a minimum length, and 3) some of the particles are in a thermal bath or otherwise evolve stochastically. We then construct simple functions of the degrees of freedom of the theory and show that their probability distributions evolve according to the Schroedinger equation. The non-local hidden variables required to satisfy the conditions of Bell's theorem are the links in the fundamental graph that connect nodes adjacent in the graph but distant in the approximate metric of the low energy limit. In the presence of these links, distant stochastic fluctuations are transferred into universal quantum fluctuations.Comment: 17 pages, 2 eps figure

Investigations of electron emission characteristics of low work function surfaces Quarterly report no. 5, 1 Oct. - 31 Dec. 1965

Electron emission characteristics of low work function surfaces from magnetic deflection probe measurements of cesium adsorption on tungste

Investigations of electron emission characteristics of low work function surfaces Quarterly report no. 2, 1 Jan. - 31 Mar. 1966

Formation and electron emission characteristics of low work function surface

Environmental dependence of AGN activity in the supercluster A901/2

We present XMM data for the supercluster A901/2, at z ~ 0.17, which is combined with deep imaging and 17-band photometric redshifts (from the COMBO-17 survey), 2dF spectra and Spitzer 24um data, to identify AGN in the supercluster. The 90ksec XMM image contains 139 point sources, of which 11 are identified as supercluster AGN with L_X(0.5-7.5keV) > 1.7x10^41 erg/cm2/s. The host galaxies have M_R < -20 and only 2 of 8 sources with spectra could have been identified as AGN by the detected optical emission lines. Using a large sample of 795 supercluster galaxies we define control samples of massive galaxies with no detected AGN. The local environments of the AGN and control samples differ at >98 per cent significance. The AGN host galaxies lie predominantly in areas of moderate projected galaxy density and with more local blue galaxies than the control sample, with the exception of one very bright Type I AGN very near the centre of a cluster. These environments are similar to, but not limited to, cluster outskirts and blue groups. Despite the large number of potential host galaxies, no AGN are found in regions with the highest galaxy density (excluding some cluster cores where emission from the ICM obscures moderate luminosity AGN). AGN are also absent from the areas with lowest galaxy density. We conclude that the prevalence of cluster AGN is linked to their environment.Comment: 20 pages, 15 figures. MNRAS accepted. Version with full resolution figures, including Figure 14, is available at http://www.sc.eso.org/~rgilmour

Investigations of electron emission characteristics of low work function surfaces Final report, 27 Sep. 1964 - 28 Sep. 1966

Electron emission characteristics of low work function surface

Vibration effects on heat transfer in cryogenic systems Quarterly progress report no. 1, Jun. 1 - Aug. 31, 1966

Vibration effects on natural convection and fluid transport properties in cryogenic system

Investigations of electron emission characteristics of low work function surfaces Quarterly report, 28 Sep. - 27 Dec. 1966

Coadsorption of cesium and fluorine on tungsten, and analysis of mechanisms leading to decay of field emission current from low work function zirconium/oxygen coated tungsten emitte

Argyrin B a non-competitive inhibitor of the human immunoproteasome exhibiting preference for β1i

Inhibitors of the proteasome have found broad therapeutic applications however, they show severe toxicity due to the abundance of proteasomes in healthy cells. In contrast, inhibitors of the immunoproteasome, which is upregulated during disease states, are less toxic and have increased therapeutic potential including against autoimmune disorders. In this project, we report argyrin B, a natural product cyclic peptide to be a reversible, non-competitive inhibitor of the immunoproteasome. Argyrin B showed selective inhibition of the β5i and β1i sites of the immunoproteasome over the β5c and β1c sites of the constitutive proteasome with nearly 20-fold selective inhibition of β1i over the homologous β1c. Molecular modelling attributes the β1i over β1c selectivity to the small hydrophobic S1 pocket of β1i and β5i over β5c to site-specific amino acid variations that enable additional bonding interactions and stabilization of the binding conformation. These findings facilitate the design of immunoproteasome selective and reversible inhibitors that may have a greater therapeutic potential and lower toxicity