3,712 research outputs found
Psychosocial factors and work related sickness absence among permanent and non-permanent employees
Study objective: To examine the association between psychosocial work factors and work related sickness absence among permanent and non-permanent employees by sex.Design: A cross sectional survey conducted in 2000 of a representative sample of the European Union total active population, aged 15 years and older. The independent variables were psychological job demands and job control as measures of psychosocial work environment, and work related sickness absence as the main outcome. Poisson regression models were used to compute sickness absence days' rate ratios.Setting: 15 countries of the European Union.Participants: A sample of permanent (n=12875) and non-permanent (n=1203) workers from the Third European Survey on Working Conditions.Results: High psychological job demands, low job control, and high strain and passive work were associated with higher work related sickness absence. The risks were more pronounced in non-permanent compared with permanent employees and men compared with women.Conclusions: This work extends previous research on employment contracts and sickness absence, suggesting different effects depending on psychosocial working conditions and sex
Exceptional Outgroup Stereotypes and White Racial Inequality Attitudes toward Asian Americans
Stereotypes of outgroups help create social identificational boundaries for ingroups. When the ingroup is dominant, members employ individualist sentiments to justify their status. In this study, we build on advances in social psychological research that account for multiple outgroup stereotypes. We argue the Asian American model minority stereotype is analogous to the “cold but competent” position of perceptions toward Asians in Fiske’s stereotype content model. Asian Americans are perceived to be exceptional to other minority groups, and we hypothesize that perceived competence is associated with individualist sentiments directed at Blacks and Latinos. Using data from the National Longitudinal Study of Freshmen, we find support for our hypotheses but find that perceived coldness has no relationship to individualist sentiments. We discuss the implications and directions for further research
A Profile Likelihood Analysis of the Constrained MSSM with Genetic Algorithms
The Constrained Minimal Supersymmetric Standard Model (CMSSM) is one of the
simplest and most widely-studied supersymmetric extensions to the standard
model of particle physics. Nevertheless, current data do not sufficiently
constrain the model parameters in a way completely independent of priors,
statistical measures and scanning techniques. We present a new technique for
scanning supersymmetric parameter spaces, optimised for frequentist profile
likelihood analyses and based on Genetic Algorithms. We apply this technique to
the CMSSM, taking into account existing collider and cosmological data in our
global fit. We compare our method to the MultiNest algorithm, an efficient
Bayesian technique, paying particular attention to the best-fit points and
implications for particle masses at the LHC and dark matter searches. Our
global best-fit point lies in the focus point region. We find many
high-likelihood points in both the stau co-annihilation and focus point
regions, including a previously neglected section of the co-annihilation region
at large m_0. We show that there are many high-likelihood points in the CMSSM
parameter space commonly missed by existing scanning techniques, especially at
high masses. This has a significant influence on the derived confidence regions
for parameters and observables, and can dramatically change the entire
statistical inference of such scans.Comment: 47 pages, 8 figures; Fig. 8, Table 7 and more discussions added to
Sec. 3.4.2 in response to referee's comments; accepted for publication in
JHE
AVALIAÇÃO DE BRUXISMO NA INFÂNCIA – RELATO DE CASO CLINICO
Introdução: O bruxismo é um hábito parafuncional caracterizado pelo rangido e/ou apertamento dos dentes, sendo inconsciente. Sua etiologia é multifuncional e existem fatores psicológicos, como estresse e ansiedade, e fatores neurofisiológicos, ligados a alterações do sono
Identification of Colletotrichum species associated with anthracnose disease of coffee in Vietnam
Colletotrichum gloeosporioides, C. acutatum, C. capsici and C. boninense associated with anthracnose disease on coffee (Coffea spp.) in Vietnam were identified based on morphology and DNA analysis. Phylogenetic analysis of DNA sequences from the internal transcribed spacer region of nuclear rDNA and a portion of mitochondrial small subunit rRNA were concordant and allowed good separation of the taxa. We found several Colletotrichum isolates of unknown species and their taxonomic position remains unresolved. The majority of Vietnamese isolates belonged to C. gloeosporioides and they grouped together with the coffee berry disease (CBD) fungus, C. kahawae. However, C. kahawae could be distinguished from the Vietnamese C. gloeosporioides isolates based on ammonium tartrate utilization, growth rate and pathogenictity. C. gloeosporioides isolates were more pathogenic on detached green berries than isolates of the other species, i.e. C. acutatum, C capsici and C. boninense. Some of the C. gloeosporioides isolates produced slightly sunken lesion on green berries resembling CBD symptoms but it did not destroy the bean. We did not find any evidence of the presence of C. kahawae in Vietnam
Evidence maps and evidence gaps: evidence review mapping as a method for collating and appraising evidence reviews to inform research and policy
Evidence reviews are a key mechanism for incorporating extensive, complex and specialised evidence into policy and practice, and in guiding future research. However, evidence reviews vary in scope and methodological rigour, creating several risks for decision-makers: decisions may be informed by less reliable reviews; apparently conflicting interpretations of evidence may obfuscate decisions; and low quality reviews may create the perception that a topic has been adequately addressed, deterring new syntheses (cryptic evidence gaps). We present a new approach, evidence review mapping, designed to produce a visual representation and critical assessment of the review landscape for a particular environmental topic or question. By systematically selecting and describing the scope and rigour of each review, this helps guide non-specialists to the most relevant and methodologically reliable reviews. The map can also direct future research through the identification of evidence gaps (whether cryptic or otherwise) and redundancy (multiple reviews on similar questions). We consider evidence review mapping a complementary approach to systematic reviews and systematic maps of primary literature and an important tool for facilitating evidence-based decision-making and research efficiency
Klebsiella pneumoniae is able to trigger epithelial-mesenchymal transition process in cultured airway epithelial cells
The ability of some bacterial pathogens to activate Epithelial-Mesenchymal Transition normally is a consequence of the persistence of a local chronic inflammatory response or depends on a direct interaction of the pathogens with the host epithelial cells. In this study we monitored the abilities of the K. pneumoniae to activate the expression of genes related to EMT-like processes and the occurrence of phenotypic changes in airway epithelial cells during the early steps of cell infection. We describe changes in the production of intracellular reactive oxygen species and increased HIF-1α mRNA expression in cells exposed to K. pneumoniae infection. We also describe the upregulation of a set of transcription factors implicated in the EMT processes, such as Twist, Snail and ZEB, indicating that the morphological changes of epithelial cells already appreciable after few hours from the K. pneumoniae infection are tightly regulated by the activation of transcriptional pathways, driving epithelial cells to EMT. These effects appear to be effectively counteracted by resveratrol, an antioxidant that is able to exert a sustained scavenging of the intracellular ROS. This is the first report indicating that strains of K. pneumoniae may promote EMT-like programs through direct interaction with epithelial cells without the involvement of inflammatory cells
Positron emission tomography scan can be a reassuring tool to treat difficult cases of infective endocarditis
The Surgical Infection Society revised guidelines on the management of intra-abdominal infection
Background: Previous evidence-based guidelines on the management of intra-abdominal infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and 2010. At the time the most recent guideline was released, the plan was to update the guideline every five years to ensure the timeliness and appropriateness of the recommendations.
Methods: Based on the previous guidelines, the task force outlined a number of topics related to the treatment of patients with IAI and then developed key questions on these various topics. All questions were approached using general and specific literature searches, focusing on articles and other information published since 2008. These publications and additional materials published before 2008 were reviewed by the task force as a whole or by individual subgroups as to relevance to individual questions. Recommendations were developed by a process of iterative consensus, with all task force members voting to accept or reject each recommendation. Grading was based on the GRADE (Grades of Recommendation Assessment, Development, and Evaluation) system; the quality of the evidence was graded as high, moderate, or weak, and the strength of the recommendation was graded as strong or weak. Review of the document was performed by members of the SIS who were not on the task force. After responses were made to all critiques, the document was approved as an official guideline of the SIS by the Executive Council.
Results: This guideline summarizes the current recommendations developed by the task force on the treatment of patients who have IAI. Evidence-based recommendations have been made regarding risk assessment in individual patients; source control; the timing, selection, and duration of antimicrobial therapy; and suggested approaches to patients who fail initial therapy. Additional recommendations related to the treatment of pediatric patients with IAI have been included.
Summary: The current recommendations of the SIS regarding the treatment of patients with IAI are provided in this guideline
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