150 research outputs found

    Uncertainties in import/export studies and the outwelling theory. An analysis with the support of hydrodynamic modelling

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    According to the “outwelling theory”, salt marshes are net exporters of primary production. This view has been contested, inducing a considerable interest in the subject. Both theses are based on annual budgets of organic matter exchange across salt marsh boundaries. These budgets are a function of integrated fluxes computed from water discharge and concentration of solutes and suspensates. Inaccuracies can follow from errors in velocity measurement and subsequent flow rate calculations as well as from analytical errors. Furthermore, the oscillatory nature of tidal transport implies that net budgets are at present one order of magnitude lower than total fluxes. Therefore, only rather more accurate methods can lead to safe conclusions on this issue. Moreover, a number of other fundamental uncertainties remain with the processing of organic matter in salt marsh sediments. These questions are discussed within the framework of the results of a European comparative salt marsh study on the Mira estuary in Portugal. Hydrodynamic modelling has been shown to be a useful tool particularly in situations where velocities are most of the time bellow the range of accuracy of commercial current meters (< 5 cm s-1)

    Inactivation of Listeria monocytogenes by pulsed light in packaged and sliced salpicĂŁo, a ready-to-eat traditional cured smoked meat sausage

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    The efficacy of pulsed light (PL) for the surface decontamination of a sliced ready-to-eat cured meat product, salpicão, was studied. The surface of the slices was inoculated with Listeria monocytogenes (107 cfu/g), and then PL treatment was applied. Microbial analyses (L. monocytogenes, coagulase-negative Staphylococci (CNS), Lactic acid bacteria (LAB) and Enterobacteriaceae) were performed immediately after the treatment. pH, aw, colour and volatile profile were also evaluated. Response Surface experimental Design was applied regarding factors voltage (ranging from 1828 to 3000 V) and distance (ranging from 2.6 to 5 cm) to the light source, and a maximum of 16.11 J/cm2 energy dose was achieved. A reduction of 1.58 log cfu/g in L. monocytogenes count was obtained when a fluence of 5.31 J/cm2 was applied. Enterobacteriaceae, LAB and CNS endogenous microbial populations were not influenced by PL treatment. PL application reduced a* values and influenced b* values without impacting the sample ΔE or L* values. The potential oxidative effect of this technology was evaluated by solid-phase microextraction (SPME) and gas chromatography-mass spectrometry (GC-MS), and no significant changes were verified after its application in this sliced cured meat product.info:eu-repo/semantics/publishedVersio

    N-terminal-pro-B type natriuretic peptide as a useful tool to evaluate pulmonary hypertension and cardiac function in CDH infants

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    Objective: In congenital diaphragmatic hernia (CDH) the severity of pulmonary hypertension (PH) is considered, by several authors, determinant of clinical outcome. Plasmatic N-terminal-pro-B type natriuretic peptide (NT-proBNP) might be useful in diagnosis and management of PH in newborns, although its interest in CDH infants remains to be defined. Early NT-proBNP levels were assessed in CDH infants and correlated with cardiovascular echocardiographic parameters. Patients and Methods: 28 newborns, CDH and age-matched controls were enrolled in a prospective study. Clinical condition, NT-proBNP plasmatic levels, echo parameters of PH and biventricular function were assessed at 24 h after delivery as well as survival outcome. Results: Estimated mean pulmonary pressure and NT-proBNP were significantly higher in CDH than control infants. NT-proBNP significantly correlated with estimated pulmonary artery pressure, right ventricular Tei index, and tricuspid E/A ratio. Additionally, we found that CDH infants with NT-proBNP >11,500 pg/ml experienced a worse prognosis. Conclusions: We demonstrated that PH is associated with NT-proBNP elevation and diastolic impairment in CDH infants. Early elevations in NT-proBNP levels seem to alert for a subset of CDH infants with worse prognosis. Copyrigh

    As mĂșltiplas funçÔes da agricultura familiar: um estudo no assentamento Monte Alegre, regiĂŁo de Araraquara (SP).

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    A partir da emergĂȘncia da ideia de sustentabilidade, a agricultura adquiriu novas conotaçÔes, associadas nĂŁo apenas ao aspecto produtivo, mas tambĂ©m Ă  conservação dos recursos naturais e dos territĂłrios rurais, em um reconhecimento de sua multifuncionalidade. Com base nesta noção, que valoriza as funçÔes socioambientais desempenhadas pelas famĂ­lias rurais e pelas agriculturas praticadas, o presente artigo analisa um assentamento rural no estado de SĂŁo Paulo, buscando identificar quais sĂŁo e de que forma se expressam as funçÔes para alĂ©m da produção neste territĂłrio particular. Por meio de uma metodologia de cunho quali-quantitativo, observou-se que, no assentamento em foco, a agricultura encerra em si questĂ”es de coesĂŁo territorial, manutenção da segurança alimentar, conservação da agrobiodiversidade e de fomento a outras atividades produtivas, sendo o elemento central da reconstrução de um modo de vida rural neste ambiente

    Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

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    Nearly 100 loci have been identified for pulmonary function, almost exclusively in studies of European ancestry populations. We extend previous research by meta-analyzing genome-wide association studies of 1000 Genomes imputed variants in relation to pulmonary function in a multiethnic population of 90,715 individuals of European (N = 60,552), African (N = 8429), Asian (N = 9959), and Hispanic/Latino (N = 11,775) ethnicities. We identify over 50 additional loci at genome-wide significance in ancestry-specific or multiethnic meta-analyses. Using recent fine-mapping methods incorporating functional annotation, gene expression, and differences in linkage disequilibrium between ethnicities, we further shed light on potential causal variants and genes at known and newly identified loci. Several of the novel genes encode proteins with predicted or established drug targets, including KCNK2 and CDK12. Our study highlights the utility of multiethnic and integrative genomics approaches to extend existing knowledge of the genetics of l
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