Hak Asasi Manusia Dalam Pendidikan

In our everyday discourse many good things have been done and attributed for the sake of wellbeing of children. This paper questions the effectiveness of what we have been doing in education in the name of children by, first, portraying children and adolescents according to recent scholarship, and then presenting problems in our current educational practice. To address the problems which arise from the observation, some strategic steps are then presented to conclude the discussio

Feature Extraction Method using HoG with LTP for Content-Based Medical Image Retrieval

An accurate diagnosis is significant for the treatment of any disease in its early stage. Content-Based Medical Image Retrieval (CBMIR) is used to find similar medical images in a huge database to help radiologists in diagnosis. The main difficulty in CBMIR is semantic gaps between the lower-level visual details, captured by computer-aided tools and higher-level semantic details captured by humans. Many existing methods such as Manhattan Distance, Triplet Deep Hashing, and Transfer Learning techniques for CBMIR were developed but showed lower efficiency and the computational cost was high. To solve such issues, a new feature extraction approach is proposed using Histogram of Gradient (HoG) with Local Ternary Pattern (LTP) to automatically retrieve medical images from the Contrast-Enhanced Magnetic Resonance Imaging (CE-MRI) database. Adam optimization algorithm is utilized to select features and the Euclidean measure calculates the similarity for query images. From the experimental analysis, it is clearly showing that the proposed HoG-LTP method achieves higher accuracy of 98.8%, a sensitivity of 98.5%, and a specificity of 99.416%, which is better when compared to the existing Random Forest (RF) method which displayed an accuracy, sensitivity, and specificity of 81.1%, 81.7% and 90.5% respectively

THERMAL ANALYSIS OF AUTOMOTIVE CYLINDER HEAD MADE BY ALUMINIUM METAL MATRIX COMPOSITE REINFORCED WITH NANO ALUMINA

Metal Matrix Nano Composites (MMNC’s) have been developed to meet the demand for lighter materials with significant improvements in mechanical and physical properties like high strength, excellent wear resistance, good thermal conductivity, low thermal expansion coefficient with particulate reinforcements. Aluminium based nano composites (AA356 – nano Al2O3) with three different percentage (1%, 1.5%, 2.5% Wt) of nano – alumina particulate reinforcement (~40 nm) were fabricated using in-situ stir casting technique. Mechanical properties characterization which strongly depends on microstructural properties of reinforcement revealed that the presence of nano – alumina particulates lead to simultaneous increase in hardness, UTS, wear behaviour. The results revealed that UTS, Hardness, Wear behaviour increases with the increase in the percentage of reinforcement of nano – Al2O3 whereas the thermal conductivity drops with increasing percentage of reinforcement when compared to the base alloy AA356. An attempt is made in the present study to review the opportunities of using such a MMNC developed in automotive brake drum replacing the current system using cast iron

Indonesian Teachers’ Beliefs and Experiences of Computer-Based English Summative Tests

Computer-Based English Summative Test (CBEST) has gained popularity in many educational institutions recently. In this testing mode, students do the exam with the help of computer in language laboratory. The result of the test is usually gained immediately after the test is done. Though CBEST has been popular, the implementation of CBEST in Indonesian educational context has not been widely published. This paper specifically presents teachers\u27 beliefs and experiences in doing CBEST testing mode. The data were collected by distributing questionnaire to 9 (nine) English teachers from 3 (three) different vocational schools. The result of the study showed that teachers believe that the implementation of CBEST give them benefits in several aspects, such as aspect of economy, aspect of system implementation and aspect of test administration and design.

2,3-Dibromo-3-(4-chloro­phen­yl)-1-(2-hy­droxy­phen­yl)propan-1-one

In the title mol­ecule, C15H11Br2ClO2, an S(6) ring motif is formed via an intra­molecular O—H⋯O hydrogen bond. The dihedral angle formed between the chloro- and hy­droxy-substituted benzene rings is 34.10 (15)°. In the crystal, weak inter­molecular C—H⋯O hydrogen bonds link the mol­ecules into chains along the c axis

Papaverine, a phosphodiesterase 10A inhibitor, ameliorates quinolinic acid-induced synaptotoxicity in human cortical neurons

Phosphodiesterase-10A (PDE10A) hydrolyse the secondary messengers cGMP and cAMP, two molecules playing important roles in neurodevelopment and brain functions. PDE10A is associated to progression of neurodegenerative diseases like Alzheimer's, Parkinson's, Huntington's diseases, and a critical role in cognitive functions. The present study was undertaken to determine the possible neuroprotective effects and the associated mechanism of papaverine (PAP), a PDE10A isoenzyme inhibitor, against quinolinic acid (QUIN)-induced excitotoxicity using human primary cortical neurons. Cytotoxicity potential of PAP was analysed using MTS assay. Reactive oxygen species (ROS) and mitochondrial membrane potential were measured by DCF-DA and JC10 staining, respectively. Caspase 3/7 and cAMP levels were measured using ELISA kits. Effect of PAP on the CREB, BNDF and synaptic proteins such as SAP-97, synaptophysin, synapsin-I, and PSD-95 expression was analysed by Western blot. Pre-treatment with PAP increased intracellular cAMP and nicotinamide adenine dinucleotide (NAD(+)) levels, restored mitochondrial membrane potential (Delta psi m), and decreased ROS and caspase 3/7 content in QUIN exposed neurons. PAP up-regulated CREB and BDNF, and synaptic protein expression. In summary, these data indicate that PDE10A is involved in QUIN-mediated synaptotoxicity and its inhibition elicit neuroprotection by reducing the oxidative stress and protecting synaptic proteins via up-regulation of cAMP signalling cascade

(2E)-3-(3-Benzyl­oxyphen­yl)-1-(2-hydroxy-5-methyl­phen­yl)prop-2-en-1-one

In the mol­ecule of the title compound, C23H20O3, an intra­molecular O—H⋯O hydrogen bond generates an S(6) ring. The central benzene ring makes dihedral angles of 80.17 (8) and 16.99 (7)°, respectively, with the benz­yloxy and hy­droxy­methyl phenyl rings. In the crystal, mol­ecules are linked via inter­molecular C—H⋯O hydrogen bonds to form dimers. The dimers are connected by C—H⋯O hydrogen bonds and C—H⋯π inter­actions to form columns down the b axis

(E)-3-(3,4-Dimeth­oxy­phen­yl)-1-(2-hy­droxy­phen­yl)prop-2-en-1-one

In the title compound, C17H16O4, the dihedral angle between the mean planes of the hy­droxy­phenyl and dimeth­oxy­phenyl rings is 5.9 (6)°. The mean plane of the prop-2-en-1-one group makes dihedral angles of 3.6 (0) and 2.6 (7)° with the hy­droxy­phenyl and dimeth­oxy­phenyl rings, respectively. An intra­molecular O—H⋯O hydrogen bond occurs. The crystal packing is stabilized by weak inter­molecular C—H⋯O contacts and π–π stacking inter­actions [centroid–centroid distance = 3.6571 (8) Å]

The total neutron production from the alpha induced reaction on natural Zirconium

A significant amount of alpha particles, upto $\sim$ 35 MeV are produced in the reactor environment. Alpha induced reaction on natural Zirconium, a reactor component, upto 40 MeV has been measured using stacked foil activation technique. The total neutron production cross section from all possible channels for $\alpha$ energies upto 35 MeV is also estimated using TALYS 1.96. The isomeric cross section ratio for the production of the radionuclide $^{95}Nb$ has been measured and reported for the first time