Analytical Modelling of Power Efficient Reliable Operation of Data Fusion in Wireless Sensor Network

Irrespective of inclusion of Wireless Sensor Network (WSN) in majority of the research proposition for smart city planning, it is still shrouded with some significant issues. A closer look into problems in WSN shows that energy parameter is the origination point of majority of the other problems in resource-constrained sensors as well as it significant minimizes the reliability in standard sensory operation in adverse environment. Therefore, this manuscript presents a novel analytical model that is meant for establishing a well balance between energy efficiency over multi-path data forwarding and reliable operation with improved network performance. The complete process is emphasized during data fusion stage to ensure data quality too. A simulation study has been carried out using benchmarked test-bed of MEMSIC nodes to find that proposed system offers good energy conservation process during data fusion operation as well as it also ensure good reliable operation in comparison to existing system

Modeling a Coronal Mass Ejection as a Magnetized Structure with EUHFORIA

We studied an Earth-directed coronal mass ejection (CME) that erupted on 2015 March 15. Our aim was to model the CME flux rope as a magnetized structure using the European Heliospheric Forecasting Information Asset (EUHFORIA). The flux rope from eruption data (FRED) output was applied to the EUHFORIA spheromak CME model. In addition to the geometrical properties of the CME flux rope, we needed to input the parameters that determine the CME internal magnetic field like the helicity, tilt angle, and toroidal flux of the CME flux rope. According to the FRED technique geometrical properties of the CME flux rope are obtained by applying a graduated cylindrical shell fitting of the CME flux rope on the coronagraph images. The poloidal field magnetic properties can be estimated from the reconnection flux in the source region utilizing the post-eruption arcade method, which uses the Heliospheric Magnetic Imager magnetogram together with the Atmospheric Imaging Assembly (AIA) 193 angstrom images. We set up two EUHFORIA runs with RUN-1 using the toroidal flux obtained from the FRED technique and RUN-2 using the toroidal flux that was measured from the core dimming regions identified from the AIA 211 angstrom images. We found that the EUHFORIA simulation outputs from RUN-1 and RUN-2 are comparable to each other. Overall using the EUHFORIA spheromak model, we successfully obtained the magnetic field rotation of the flux rope, while the arrival time near Earth and the strength of the interplanetary CME magnetic field at Earth are not as accurately modeled.Peer reviewe

ADVANCED RECEIVER ARCHITECTURES IN RADIOFREQUENCY APPLICATIONS

The general principles of several types of receivers fall under the two main headings of TRF (tuned radio frequency)receivers, where the received signal is processed at the incoming frequency right up to the detector stage, and the superhet(supersonic heterodyne) receiver, where the incoming signal is translated (sometimes after some amplification at theincoming frequency) to an intermediate frequency for further processing. There are however, a number of variants of each ofthese two main types. Regeneration (‘reaction’ or ‘tickling’) may be applied in a TRF receiver, to increase both its sensitivityand selectivity. This may be carried to the stage where the RF amplifier actually oscillates – either continuously, so that thereceiver operates as a synchrodyne or homodyne, or intermittently, so that the receiver operates as a super-regenerativereceiver, both of which have been described previously. The synchrodyne or homodyne may be considered alternatively as asuperhet, where the IF (intermediate frequency) is 0 Hz. In this paper we present the new type of receiver architectureswhich work in radiofrequencies.Keywords: supersonic heterodyne, tuned radio frequency

Crystal structure of 1-benzylsulfonyl-1,2,3,4-tetrahydroquinoline

SJ thanks the Vision Group on Science and Technology, Government of Karnataka, for the award of a major project under the CISE scheme (reference No. VGST/CISE/GRD192/2013-14). BSPM thanks Rajegowda, Department of Studies and Research in Chemistry, UCS, Tumkur University, Karnataka 572 103, India, for his support.Peer reviewedPublisher PD

Proper qq-caterpillars are distinguished by their Chromatic Symmetric Functions

Stanley's Tree Isomorphism Conjecture posits that the chromatic symmetric function can distinguish non-isomorphic trees. While already established for caterpillars and other subclasses of trees, we prove the conjecture's validity for a new class of trees that generalize proper caterpillars, thus confirming the conjecture for a broader class of trees.Comment: 11 page

DESIGN AND DEVELOPMENT OF ORAL SUSTAINED RELEASE MATRIX TABLETS OF DIDANOSINE

Objectives: In present study, an attempt was made to design sustained-release tablets containing Didanosine using natural gums like Xanthan gum, Guar gum and Karaya gum. Methods: The sustained-release tablets containing Didanosine prepared by using natural gums by wet granulation method. Influence of natural polymer on Didanosine was studied. The prepared tablets were selected for DSC and FTIR studies.Results and Discussions: The tablets were selected for DSC and FTIR studies did not show any chemical interaction between drug and polymer. The prepared formulations were evaluated for Hardness, Thickness, Friability, Weight variation, drug content estimation, Swelling index, in-vitro drug release are within the acceptable standard. In-vitro release profile was check for 8 hrs to evaluate the SR matrix tablet of Didanosine. The optimized tablets were carried out according to ICH guidelines at 40 ± 2º C/ 75 ± 5percent RH for three months. All the prepared tablets were stable at room temperature. The values of pre-compression parameters of prepared granules were evaluated the results were within prescribed limits and indicated good free flowing property. The prepared tablets were subjected to all the quality control tests they were within the official pharmacopoeial limits. Friability is less than 1percent, indicated that tablets had a good mechanical resistance. Weight variation test revealed that the tablets were within the range of pharmacopoeial limit. Thickness, hardness and drug content were within the range of pharmacopoeial limit. The evaluation parameters were within acceptable range for all the formulations. The in-vitro release of Didanosine was conducted for 8 hrs. The optimized formulations WGX3, WGG5 and WGK9 sustained the release up to 8hr. Hence Didanosine along with Xanthan gum, Guar gum and Karaya Gum could be used to prepared sustained released matrix tablets. The in-vitro release obeyed zero order kinetics with mechanism of release was erosion followed by non-fickian diffusion.Conclusion: Among all the formulations WGK9 is the best shows excellent release around 99percent after 8 hrs. The prepared matrix tablets of Didanosine were stable. So, it may be concluded that sustained release matrix tablets would improve the patient compliance and bioavailability may be improved. Keywords:  Didanosine, Xanthan gum, Guar gum and Karaya gum

Structure and stability of glucoamylase II from Aspergillus niger: a circular dichroism study

Glucoamylase II (EC 3.2.1.3) from Aspergillus niger has 31 % α-helix, 36 % β-structure and rest aperiodic structure at pH 4.8 as analysed by the method of Provencher and Glockner (1981,Biochemistry, 20,33). In the near ultra-violet circular dichroism spectrum the enzyme exhibits peaks at 304, 289, 282 and 257 nm and troughs at 285, 277 and 265 nm respectively. The enzyme activity and structure showed greater stability at pH 4.8 than at pH 7.0, were highly sensitive to alkaline pH but less sensitive to acid pH values. The enzyme retained most of its catalytic activity and structure even on partial removal of carbohydrate moieties by periodate treatment but was less stable at higher temperatures and storage at 30‡C. Reduction of the periodate treated enzyme did not reverse the loss of stability. Binding of the synthetic substrate, p-nitrophenyl-α-D-glucoside, perturbed the environment around aromatic amino acids and caused a decrease in the ordered structure

Measurement of Differentially Methylated INS DNA Species in Human Serum Samples as a Biomarker of Islet β Cell Death

The death of islet β cells is thought to underlie the pathogenesis of virtually all forms of diabetes and to precede the development of frank hyperglycemia, especially in type 1 diabetes. The development of sensitive and reliable biomarkers of β cell death may allow for early therapeutic intervention to prevent or delay the development of diabetes. Recently, several groups including our own have reported that cell-free, differentially methylated DNA encoding preproinsulin (INS) in the circulation is correlated to β cell death in pre-type 1 diabetes and new-onset type 1 diabetes. Here, we present a step-by-step protocol using digital PCR for the measurement of cell-free INS DNA that is differentially methylated at cytosine at position -69 bp (relative to the transcriptional start site). We demonstrate that the assay can distinguish between methylated and unmethylated cytosine at position -69 bp, is linear across several orders of magnitude, provides absolute quantitation of DNA copy numbers, and can be applied to samples of human serum from individuals with new-onset type 1 diabetes and disease-free controls. The protocol described here can be adapted to any DNA species for which detection of differentially methylated cytosines is desired, whether from circulation or from isolated cells and tissues, and can provide absolute quantitation of DNA fragments

Floral biology studies in wild melon [Cucumis melo L. ssp. agrestis (Naudin) Pangalo var. agrestis Naudin]

Studies on floral morphology, phenology and biology of wild melon revealed that the ratio of staminate and pistillate flowers was 3.40:1. The longevity of the male flowers were between 5 and 6 days, whereas, female flowers between 6 and 7 days. Anthesis was observed from 4.00 am to 10.00 am, while, the anther dehiscence started from 5.00 am which was continued to 7.00 am. The peak anthesis was observed from 8.00 am to 9.00 am and anther dehiscence from 6.00 am to 6.30 am. Freshly opened flowers showed pollen viability up to 98.35%, decreased upon closure and crashed to 17.48% in 3 days. Pollen germination was occurred after 15 minutes of incubation and continued up to 24 h of incubation. The stigma receptivity lasts from one to two days of anthesis. Major pollinator of wild melons observed was honey bee, mostly visited between 9:00 am to 6:00 pm

First report of the occurrence of Myrothecium verrucaria in watermelon seeds from India

Watermelon (Citrullus lanatus) is known to be affected by a variety of both seed-borne and soil-borne fungi. In routine screening of watermelon seed samples, sporodochia of Myrothecium verrucaria were observed. The fungus was isolated and the spore suspension was inoculated onto healthy seedlings of watermelon. The resulting symptoms confirmed Koch's postulates