3,107 research outputs found
Towards Collaborative Conceptual Exploration
In domains with high knowledge distribution a natural objective is to create
principle foundations for collaborative interactive learning environments. We
present a first mathematical characterization of a collaborative learning
group, a consortium, based on closure systems of attribute sets and the
well-known attribute exploration algorithm from formal concept analysis. To
this end, we introduce (weak) local experts for subdomains of a given knowledge
domain. These entities are able to refute and potentially accept a given
(implicational) query for some closure system that is a restriction of the
whole domain. On this we build up a consortial expert and show first insights
about the ability of such an expert to answer queries. Furthermore, we depict
techniques on how to cope with falsely accepted implications and on combining
counterexamples. Using notions from combinatorial design theory we further
expand those insights as far as providing first results on the decidability
problem if a given consortium is able to explore some target domain.
Applications in conceptual knowledge acquisition as well as in collaborative
interactive ontology learning are at hand.Comment: 15 pages, 2 figure
Plagiocephaly Perception and Prevention: A Need to Intervene Early to Educate Parents
Background: Plagiocephaly is a condition where the cranium has been malformed because of external forces or premature cranial suture fusion. This study’s objective was to gather and examine data regarding parent and caregiver awareness of plagiocephaly and its potential impact on development as well as to determine their rate of concern for positional flattening.
Method: A cross-sectional survey study was conducted. Categorical variables were described by frequency and proportions. The study was conducted across eight outpatient pediatric sites. Approximately 1,100 parents and caregivers were targeted. Inclusion criteria required participants to be willing to answer the questionnaire, to be 18 years of age or older, and to have an infant 12 months of age or younger.
Results: There were 404 participants, most of whom were female (89.8%) and 30–39 years of age (61.1%). Nineteen children (4.7%) were reported to have plagiocephaly, torticollis, and/or muscle weakness (PTM). A greater percentage of the participants with a child with PTM knew of positional flattening or plagiocephaly (73.3%) compared to those without (53.8%). The respondents with a child with PTM had a greater concern about plagiocephaly than those without (p = .03). Many of the respondents (65.3%) would use a device designed to prevent plagiocephaly.
Conclusion: Many parents and caregivers were unaware of plagiocephaly and its potential impact on facial symmetry. A greater percentage of the participants with a child with PTM knew of positional flattening and also had a greater concern about plagiocephaly than those without
Diffractive Optics for Gravitational Wave Detectors
All-reflective interferometry based on nano-structured diffraction gratings
offers new possibilities for gravitational wave detection. We investigate an
all-reflective Fabry-Perot interferometer concept in 2nd order Littrow mount.
The input-output relations for such a resonator are derived treating the
grating coupler by means of a scattering matrix formalism. A low loss
dielectric reflection grating has been designed and manufactured to test the
properties of such a grating cavity
Effects of interaction on an adiabatic quantum electron pump
We study the effects of inter-electron interactions on the charge pumped
through an adiabatic quantum electron pump. The pumping is through a system of
barriers, whose heights are deformed adiabatically. (Weak) interaction effects
are introduced through a renormalisation group flow of the scattering matrices
and the pumped charge is shown to {\it always} approach a quantised value at
low temperatures or long length scales. The maximum value of the pumped charge
is set by the number of barriers and is given by . The
correlation between the transmission and the charge pumped is studied by seeing
how much of the transmission is enclosed by the pumping contour. The (integer)
value of the pumped charge at low temperatures is determined by the number of
transmission maxima enclosed by the pumping contour. The dissipation at finite
temperatures leading to the non-quantised values of the pumped charge scales as
a power law with the temperature (), or with
the system size (), where is a
measure of the interactions and vanishes at . For a double
barrier system, our result agrees with the quantisation of pumped charge seen
in Luttinger liquids.Comment: 9 pages, 9 figures, better quality figures available on request from
author
Demonstration of 3-port grating phase relations
We experimentally demonstrate the phase relations of 3-port gratings by
investigating 3-port coupled Fabry-Perot cavities. Two different gratings which
have the same 1st order diffraction efficiency but differ substantially in
their 2nd order diffraction efficiency have been designed and manufactured.
Using the gratings as couplers to Fabry-Perot cavities we could validate the
results of an earlier theoretical description of the phases at a three port
grating
A cognitive map in a poison frog
© 2019. Published by The Company of Biologists Ltd A fundamental question in cognitive science is whether an animal can use a cognitive map. A cognitive map is a mental representation of the external world, and knowledge of one’s place in this world, that can be used to determine efficient routes to any destination. Many birds and mammals are known to employ a cognitive map, but whether other vertebrates can create a cognitive map is less clear. Amphibians are capable of using beacons, gradients and landmarks when navigating, and many are proficient at homing. Yet only one prior study directly tested for a cognitive map in amphibians, with negative results. Poison frogs exhibit unusually complex social and spatial behaviors and are capable of long-distance homing after displacement, suggesting that they may be using complex spatial navigation strategies in nature. Here, we trained the poison frog Dendrobates auratus in a modified Morris water maze that was designed to suppress thigmotaxis to the maze wall, promoting exploration of the arena. In our moat maze, the poison frogs were able to use a configuration of visual cues to find the hidden platform. Moreover, we demonstrate that they chose direct paths to the goal from multiple random initial positions, a hallmark of a cognitive map. The performance of the frogs in the maze was qualitatively similar to that of rodents, suggesting that the potential to evolve a cognitive map is an evolutionarily conserved trait of vertebrates
Billiard Systems in Three Dimensions: The Boundary Integral Equation and the Trace Formula
We derive semiclassical contributions of periodic orbits from a boundary
integral equation for three-dimensional billiard systems. We use an iterative
method that keeps track of the composition of the stability matrix and the
Maslov index as an orbit is traversed. Results are given for isolated periodic
orbits and rotationally invariant families of periodic orbits in axially
symmetric billiard systems. A practical method for determining the stability
matrix and the Maslov index is described.Comment: LaTeX, 19 page
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Protocol-directed sedation versus non-protocol-directed sedation to reduce duration of mechanical ventilation in mechanically ventilated intensive care patients
Background
The sedation needs of critically ill patients have been recognized as a core component of critical care and meeting these is vital to assist recovery and ensure humane treatment. There is growing evidence to suggest that sedation requirements are not always optimally managed. Sub-optimal sedation incorporates both under- and over-sedation and has been linked to both short-term (e.g. length of stay) and long-term (e.g. psychological recovery) outcomes. Various strategies have been proposed to improve sedation management and address aspects of assessment as well as delivery of sedation.
Objectives
To assess the effects of protocol-directed sedation management on the duration of mechanical ventilation and other relevant patient outcomes in mechanically ventilated intensive care unit (ICU) patients. We looked at various outcomes and examined the role of bias in order to examine the level of evidence for this intervention.
Search methods
We searched the Cochrane Central Register of Controlled trials (CENTRAL) (2013; Issue 11), MEDLINE (OvidSP) (1990 to November 2013), EMBASE (OvidSP) (1990 to November 2013), CINAHL (BIREME host) (1990 to November 2013), Database of Abstracts of Reviews of Effects (DARE) (1990 to November 2013), LILACS (1990 to November 2013), Current Controlled Trials and US National Institutes of Health Clinical Research Studies (1990 to November 2013), and reference lists of articles. We re-ran the search in October 2014. We will deal with any studies of interest when we update the review.
Selection criteria
We included randomized controlled trials (RCTs) conducted in adult ICUs comparing management with and without protocol-directed sedation.
Data collection and analysis
Two authors screened the titles and abstracts and then the full-text reports identified from our electronic search. We assessed seven domains of potential risk of bias for the included studies. We examined the clinical, methodological and statistical heterogeneity and used the random-effects model for meta-analysis where we considered it appropriate. We calculated the mean difference (MD) for duration of mechanical ventilation and risk ratio (RR) for mortality across studies, with 95% confidence intervals (CI).
Main results
We identified two eligible studies with 633 participants. Both included studies compared the use of protocol-directed sedation, specifically protocols delivered by nurses, with usual care. We rated the risk of selection bias due to random sequence generation low for one study and unclear for one study. The risk of selection bias related to allocation concealment was low for both studies. We also assessed detection and attrition bias as low for both studies while we considered performance bias high due to the inability to blind participants and clinicians in both studies. Risk due to other sources of bias, such as potential for contamination between groups and reporting bias, was considered unclear. There was no clear evidence of differences in duration of mechanical ventilation (MD -5.74 hours, 95% CI -62.01 to 50.53, low quality evidence), ICU length of stay (MD -0.62 days, 95% CI -2.97 to 1.73) and hospital length of stay (MD -3.78 days, 95% CI -8.54 to 0.97) between people being managed with protocol-directed sedation versus usual care. Similarly, there was no clear evidence of difference in hospital mortality between the two groups (RR 0.96, 95% CI 0.71 to 1.31, low quality evidence). ICU mortality was only reported in one study preventing pooling of data. There was no clear evidence of difference in the incidence of tracheostomy (RR 0.77, 95% CI 0.31 to 1.89). The studies reported few adverse event outcomes; one study reported self extubation while the other study reported re-intubation; given this difference in outcomes, pooling of data was not possible. There was significant heterogeneity between studies for duration of mechanical ventilation (I2 = 86%, P value = 0.008), ICU length of stay (I2 = 82%, P value = 0.02) and incidence of tracheostomy (I2 = 76%, P value = 0.04), with one study finding a reduction in duration of mechanical ventilation and incidence of tracheostomy and the other study finding no difference.
Authors' conclusions
There is currently insufficient evidence to evaluate the effectiveness of protocol-directed sedation. Results from the two RCTs were conflicting, resulting in the quality of the body of evidence as a whole being assessed as low. Further studies, taking into account contextual and clinician characteristics in different ICU environments, are necessary to inform future practice. Methodological strategies to reduce the risk of bias need to be considered in future studies
The ethics of inherent trust in care robots for the elderly
The way elderly care is delivered is changing. Attempts are being made to accommodate the increasing number of elderly, and the decline in the number of people available to care for them, with care robots. This change introduces ethical issues into robotics and healthcare. The two-part study (heuristic evaluation and survey) reported here examines a phenomenon which is a result of that
change. The phenomenon rises out of a contradiction. All but 2 (who were undecided) of the 12 elderly survey respondents, out of the total of 102 respondents, wanted to be able to change how the presented care robot made decisions and 7 of those 12 elderly wanted to be able to examine its decision making process so
as to ensure the care provided is personalized. However, at the same time, 34% of the elderly participants said they were willing to trust the care robot inherently, compared to only 16% of the participants who were under fifty. Additionally, 66% of the elderly respondents said they were very likely or likely to accept and
use such a care robot in their everyday lives. The contradiction of inherent trust and simultaneous wariness about control gives rise to the phenomenon: elderly in need want control over their care to ensure it is personalized, but many may desperately take any help they can get. The possible causes, and ethical implications,
of this phenomenon are the focus of this paper
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