INFLUENCE OF OZONE THERAPY AND UTROZHESTAN ON HORMONE PRODUCING FUNCTION OF FETOPLACENTAL COMPLEX AT THE THREATENING PREMATURE BIRTH AND FETOPLACENTAL INSUFFICIENCY

We researched hormonal function of fetoplacental complex (FPC) in 180 pregnant women with threatening premature birth and chronic fetoplacental insufficiency including 90 patients who received ozone therapy in combination with Utrozhestan, 90 pregnant women who received traditional therapy, and 51 woman with an uncomplicated pregnancy (control group). Corrective and. stimulating effect of ozone therapy and. Utrozhestan. on hormonal function fetoplacental complex was revealed

Stochastic contraction of myosin minifilaments drives evolution of microridge protrusion patterns in epithelial cells

Actin-based protrusions vary in morphology, stability, and arrangement on cell surfaces. Microridges are laterally elongated protrusions on mucosal epithelial cells, where they form evenly spaced, mazelike patterns that dynamically remodel by fission and fusion. To characterize how microridges form their highly ordered, subcellular patterns and investigate the mechanisms driving fission and fusion, we imaged microridges in the maturing skin of zebrafish larvae. After their initial development, microridge spacing and alignment became increasingly well ordered. Imaging F-actin and non-muscle myosin II (NMII) revealed that microridge fission and fusion were associated with local NMII activity in the apical cortex. Inhibiting NMII blocked fission and fusion rearrangements, reduced microridge density, and altered microridge spacing. High-resolution imaging allowed us to image individual NMII minifilaments in the apical cortex of cells in live animals, revealing that minifilaments are tethered to protrusions and often connect adjacent microridges. NMII minifilaments connecting the ends of two microridges fused them together, whereas minifilaments oriented perpendicular to microridges severed them or pulled them closer together. These findings demonstrate that as cells mature, cortical NMII activity orchestrates a remodeling process that creates an increasingly orderly microridge arrangement

Crystal field and exchange interactions in the SmFe3(BO 3)4 multiferroic

The optical spectra of oriented SmFe3(BO3) 4 single crystals are studied in the region of the f-f transitions in the Sm3+ ion by Fourier spectroscopy. The energies, the symmetry properties, and the exchange splittings of the Stark sublevels of the ground and 17 excited multiplets of the Sm3+ ion in a crystal field of symmetry D 3 are determined from the measured temperature dependences of polarized-radiation absorption spectra. The parameters of the crystal field acting on samarium ions and the parameters of the exchange interaction between Sm3+ and Fe3+ ions are found. The anisotropy of the effective exchange interaction is shown to be substantially stronger than the magnetic anisotropy, due to a strong crystal-field-induced mixing of the ground and excited multiplets. © 2014 Pleiades Publishing, Inc

Holmium iron borate: High-resolution spectroscopy and crystal-field parameters

© The Authors, published by EDP Sciences.High-resolution transmission spectra of HoFe3(BO3)4 single crystals were measured in broad spectral (5000-23000 cm-1) and temperature (1.7-300 K) ranges. Crystal-field energies of the Ho3+ ions were determined for a paramagnetic and easy-Axis antiferromagnetic phases of the compound. On the basis of these data and of preliminary crystal-field calculations in the frame of the exchange-charge model, crystal-field parameters were found. A parameter of the isotropic Ho-Fe exchange interaction was estimated

Nonlinear interaction of elastic waves in solid porous material under the condition of phase-group synchronism

Nonlinear interaction of quasiharmonic longitudinal waves, which propagate in solid porous material, was investigated theoretically. It was shown that as a result of such interaction between low-frequency waves (vibration field) and high-frequency waves (ultrasound) an ultrasound wave of summarized frequency would be generated. This newly generated wave can be in a phase-group synchronism with the vibration field. Analytical analysis qualitatively agrees with experimental data of ultrasound generation through seismic load

AN ANALYSIS OF REGIONAL ECONOMIC GROWTH AND CAPITAL EXPENDITURE ON SELF-GENERATED REVENUE IN SUPIORI REGENCY

The purpose of this research is to evaluate the effect of the economic growth and the capital expenditures on self-generated revenue of Supiori Regency during 2008 to 2014 partially and simultaneously. This research was a causative research aims to test hypotheses and explain the phenomenon in relation of the research variables. Data collected was from secondary sources such as government publication documents comprise of economic growth information, the amount of capital expenditures, and the region self-generated revenue. The population in this study was Audited Budget Realization Report and economic growth of Supiori Regency and Papua Province from 2008 to 2014. While the sample consisted of economic growth information based on accepted prices, capital expenditures and self-generated revenue of Supiori Regency and Papua province from 2008 to 2014. All these data being analyzed used a classical assumption test and path analysis. According to the analysis, the results showed that the economic growth of Supiori Regency has a positive and significant effect on self-generated revenue of Supiori partially and simultaneously in 2008 to 2014. While the allocation for capital expenditures from 2008 to 2014 has positive effect but not significant on the regional self-generated revenue in Supiori partially and simultaneously. Also, the allocation of capital expenditure and the economic development from 2008 to 2014 have positive but not significant effect on the regional self-generated revenue in Supiori partially and simultaneously. As can be seen from the pattern of correlation from each variables, this study concluded that the capital expenditures was not the intervening variables to the progress of the region self-generated revenue in Supiori Regency. Keywords : Self-Generated Revenue, Economic Growth, Capital Expenditur

Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling

Epithelial cell–cell junctions remodel in response to mechanical stimuli to maintain barrier function. Previously, we found that local leaks in tight junctions (TJs) are rapidly repaired by local, transient RhoA activation, termed “Rho flares,” but how Rho flares are regulated is unknown. Here, we discovered that intracellular calcium flashes and junction elongation are early events in the Rho flare pathway. Both laser-induced and naturally occurring TJ breaks lead to local calcium flashes at the site of leaks. Additionally, junction elongation induced by optogenetics increases Rho flare frequency, suggesting that Rho flares are mechanically triggered. Depletion of intracellular calcium or inhibition of mechanosensitive calcium channels (MSCs) reduces the amplitude of calcium flashes and diminishes the sustained activation of Rho flares. MSC-dependent calcium influx is necessary to maintain global barrier function by regulating reinforcement of local TJ proteins via junction contraction. In all, we uncovered a novel role for MSC-dependent calcium flashes in TJ remodeling, allowing epithelial cells to repair local leaks induced by mechanical stimuli

Evidence for a collinear easy-plane magnetic structure of multiferroic EuF e3(B O3)4: Spectroscopic and theoretical studies

© 2016 American Physical Society.We performed high-resolution polarized optical transmission spectroscopy and theoretical studies of multiferroic EuFe3(BO3)4 single crystals in the three phases: paramagnetic R32(T>Ts=84K) and P3121(Ts>T>TN=34K), and antiferromagnetic (T<TN) ones. The analysis of the spectra reveals interesting details of the magnetic structure, namely, a collinear arrangement of the iron magnetic moments along the C2 symmetry axis in the ab crystallographic plane of EuFe3(BO3)4 below TN. Spectral signatures of the phase transitions and the spin-phonon interaction are observed and discussed. Reliable crystal-field and exchange-interaction parameters are obtained and used to model the magnetic susceptibility of the compound. The results of detailed calculations of the electric polarization of EuFe3(BO3)4 in the R32 phase are presented, and mechanisms of the magnetoelectric response are discussed. We detect a strong effect of impurities (that enter the crystal from a flux in the course of the crystal growth) on the structural phase-transition temperature and demonstrate a coexistence of both R32 and P3121 phases down to the lowest temperatures in a EuFe3(BO3)4 crystal grown with the Bi2Mo3O12 based flux, due to inhomogeneous distribution of impurity Bi3+ ions. Our study can be considered as a demonstration of the abilities of optical spectroscopy in delivering new information on a magnetic compound, even in the case when other methods fail

Surface hardening of stainless steel by runaway electronspreionized diffuse discharge in air atmosphere

In this paper we present microhardness measurements of stainless steel surface treated by diffuse discharge in air atmosphere. The cleaning from carbon in comparison to the initial sample was observed at a depth exceeding 20 nm. The oxygen concentration was also increased in comparison to that in the initial sample at a depth of up to about 50 nm. Comparative analysis shows that after treatment the microhardness of stainless steel surface increased in 2 times due to interaction of near-surface layers with product of plasma chemical reactions produced in diffuse discharge