385 research outputs found

    Instagram as a Co-Creation Space for Tourist Destination Image-Building: Algarve and Costa del Sol Case Studies

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    Instagram is a popular social media platform. Its ability to convey feelings through photographs has become a valuable communication tool for tourism destination branding. The cases of two destinations in Southern Europe provide an understanding of how Instagram can be used to promote a destination’s image by Destination Management Organizations (DMOs). For this purpose, a content analysis is carried out, first of the official Instagram accounts of Algarve (Portugal) and Costa del Sol (Spain), and then of the most popular hashtags related to them, showing User-Generated Content (UGC) from the points of view of both destination managers and tourists. The results show that Instagram is a strategic social media platform for enhancing the brand image by engaging customers. Destinations seize content generated by tourists; therefore, the hermeneutic circle of representation is inverted, as photos taken by tourists aim to reproduce the perceived image of a destination and motivate tourists to capture their experiences with the best picture. Additionally, it is worth highlighting, as a main finding, the role of sustainability as a key factor in UGC for DMOs and for Instagram users. This research provides valuable information about designing promotion strategies for DMOs, in order to understand the potential of Instagram in building a destination’s image and inspiring tourism through images.This research received funds from a Plan Propio of the University of Malag

    Reading Strategies for Children with Developmental Language Disorder

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    Developmental language disorder (DLD) is considered a neurodevelopmental disorder that compromises language comprehension and/or expression and constitutes a risk factor for learning to read. The aim of the present study was to analyse the reading strategies used by students with DLD to read sentences. There is evidence in the literature that, when linguistic resources are insufficient, the keyword strategy (identifying some of the words in the sentence with their own semantic content, with barely no processing of the function words) is used to read sentences. A total of 31 primary and secondary school students diagnosed with DLD were evaluated using the PEALE battery. The results reveal that students with DLD present heterogeneous profiles that are below the established reading level for their age. In addition, children with DLD and better reading skills use the keyword strategy to read sentences. In conclusion, clinical and educational implications for reading intervention in individuals with DLD are discussed

    Métodos alternativos de muestreo para estimar la estructura y caracteres reproductivos de bosques

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    Aleppo pine had a large forest cover in North Africa and along the Mediterranean basin which management is not fully developed and new forest tools are required. In this research, the forest structure, epidometric characteristics and allometric relationships were studied in 79 plots covering four bioclimatic zones from natural even aged forests of Aleppo pine located between eastern Algeria to the western coastal part of Tunisia. To characterize the forest structure three sampling methods were carried out: classical inventories (recording all pine trees), and two simplified approach using one average size or five dominant pine tree per plot. Annual growth increment and cone production were only calculated for the average size tree. Furthermore, the analysis of variance showed non-significant differences recorded between bioclimatic zones in trunk or crown diameter using the two simplified approach. Moreover, a significant decrease from wetter to drier areas in total height, crown height, cone seed production was observed only for average size tree method. However, the analysis of covariance showed significant differences between both approaches in total height, trunk diameter and crown coverage which were largely influenced by the pine tree density. In future investigations, we confirmed previous research that the dominant tree is a good sampling method to examine the site fertility, whereas the average size tree constitutes a valuable approach to study the population growth and reproduction.El pino carrasco muestra una gran cobertura forestal, tanto en el norte de África como en toda la Cuenca Mediterránea, cuyo manejo no está totalmente desarrollado lo que requiere nuevas herramientas de manejo. En esta investigación, se estudiaron la estructura forestal, las características epidométricas y las relaciones alométricas de 79 parcelas distribuidas a lo largo de cuatro zonas bioclimáticas en bosques regulares de pino carrasco situados entre el este de Argelia y la costa este de Túnez. Para caracterizar la estructura forestal se aplicaron tres métodos de muestreo: inventario clásico (midiendo todos los pies) y dos propuestas más sencillas, usando un árbol medio o cinco pies dominantes por parcela. El análisis de varianza no mostraba diferencias significativas de las mediciones de diámetro de tronco y de copa realizadas entre las distintas zonas bioclimáticas usando ambos métodos. Por otra parte, se observó una disminución significativa de las zonas más húmedas a las más secas en altura toral, altura de copa y producción de semillas fue observada aplicando el método de árbol medio. Además, el análisis de covarianzas mostraba diferencias significativas, usando ambas metodologías, en los valores medios de altura total, diámetro de tronco y cobertura de copa que mostraron estar influenciados por los valores de la densidad de arbolado de cada zona. Para futuras investigaciones, confirmamos estudios previos que apuntaban que la propuesta de muestreo de árboles dominantes como un buen método de muestreo para caracterizar la calidad de sitio mientras que la de árbol medio constituye una valiosa propuesta para el estudio del crecimiento de poblaciones y sus características reproductivas

    Zirconia-Based Ultra-Thin Compact Flexible CPW-Fed Slot Antenna for IoT

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    An ultra-thin compact flexible CPW-fed slot monopole antenna suitable for the Internet of Things (IoT) applications was achieved as a result of exploring the use of Zirconia-based ENrG’s Thin E-Strate® for the antenna’s design. The electromagnetic characterization of the novel material at the frequency range of interest was analyzed. A comparison was made concerning the required dimensions and the simulation results regarding impedance matching and radiation properties, for three different dielectric substrates: Novel flexible ceramic (ENrG’s Thin E-Strate), rigid Arlon 25N, and flexible Polypropylene (PP). Two different metallization techniques—electrotextile-based and inkjet printing—were used in the fabrication of prototypes based on ENrG’s Thin E-Strate. Return losses measured results for the fabricated prototypes with both procedures was compared, as well as with simulation. The best prototype on the ENrG’s Thin E-Strate was compared with one on Arlon 25N, in terms of radiation properties in an anechoic chamber, and conclusions were drawn

    The success of Quercus ilex plantations in agricultural fields in eastern Spain

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    Twenty-five years after planting, we measured the survival, growth and reproduction of 153 Quercus ilex plantations promoted by the afforestation programme of the European Union’s Common Agricultural Policy in agricultural fields in the east of the Iberian Peninsula, as a function of climatic aridity and stand characteristics related to water supply and competition among trees for water. Using field sampling, we found that, on average, 80% of the trees in plantations survived, more than 55% had already produced acorns and the tallest tree in each field exceeded 4 m, which are all higher values than those reported for forest plantations of this species in the same area and which represent the overcoming of the limitations imposed by climatic aridity on the natural regeneration of the species. A small proportion of the variation in all success variables was explained by water-related plantation characteristics, such as planting density, drought intensity in the year after planting, and soil permeability. However, climatic aridity only influenced the proportion of reproductive trees, but not the other variables of plantation success. However, most of the variation in planting success variables was linked to who owned the field, which nursery produced the seedlings, and the year of planting. Our results support the idea that the deep soils of agricultural fields counteract the negative effect of climatic aridity on plant performance, but that it is necessary to standardise nursery and planting practices, adapt planting density to the environmental characteristics of the site and provide irrigation supply in the early years to ensure the success of future plantations

    Labdane diterpenes protect against anoxia/reperfusion injury in cardiomyocytes: involvement of AKT activation

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    Several labdane diterpenes exert anti-inflammatory and cytoprotective actions; therefore, we have investigated whether these molecules protect cardiomyocytes in an anoxia/reperfusion (A/R) model, establishing the molecular mechanisms involved in the process. The cardioprotective activity of three diterpenes (T1, T2 and T3) was studied in the H9c2 cell line and in isolated rat cardiomyocyte subjected to A/R injury. In both cases, treatment with diterpenes T1 and T2 protected from A/R-induced apoptosis, as deduced by a decrease in the percentage of apoptotic and caspase-3 active positive cells, a decrease in the Bcl-2/Bax ratio and an increase in the expression of antiapoptotic proteins. Analysis of cell survival signaling pathways showed that diterpenes T1 and T2 added after A/R increased phospho-AKT and phospho-ERK 1/2 levels. These cardioprotective effects were lost when AKT activity was pharmacologically inhibited. Moreover, the labdane-induced cardioprotection involves activation of AMPK, suggesting a role for energy homeostasis in their mechanism of action. Labdane diterpenes (T1 and T2) also exerted cardioprotective effects against A/R-induced injury in isolated cardiomyocytes and the mechanisms involved activation of specific survival signals (PI3K/AKT pathways, ERK1/2 and AMPK) and inhibition of apoptosis

    A multistage sequencing strategy pinpoints novel candidate alleles for Emery-Dreifuss muscular dystrophy and supports gene misregulation as its pathomechanism

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    BACKGROUND: As genome-wide approaches prove difficult with genetically heterogeneous orphan diseases, we developed a new approach to identify candidate genes. We applied this to Emery-Dreifuss muscular dystrophy (EDMD), characterised by early onset contractures, slowly progressive muscular wasting, and life-threatening heart conduction disturbances with wide intra- and inter-familial clinical variability. Roughly half of EDMD patients are linked to six genes encoding nuclear envelope proteins, but the disease mechanism remains unclear because the affected proteins function in both cell mechanics and genome regulation. METHODS: A primer library was generated to test for mutations in 301 genes from four categories: (I) all known EDMD-linked genes; (II) genes mutated in related muscular dystrophies; (III) candidates generated by exome sequencing in five families; (IV) functional candidates - other muscle nuclear envelope proteins functioning in mechanical/genome processes affected in EDMD. This was used to sequence 56 unlinked patients with EDMD-like phenotype. FINDINGS: Twenty-one patients could be clearly assigned: 18 with mutations in genes of similar muscular dystrophies; 3 with previously missed mutations in EDMD-linked genes. The other categories yielded novel candidate genes, most encoding nuclear envelope proteins with functions in gene regulation. INTERPRETATION: Our multi-pronged approach identified new disease alleles and many new candidate EDMD genes. Their known functions strongly argue the EDMD pathomechanism is from altered gene regulation and mechanotransduction due to connectivity of candidates from the nuclear envelope to the plasma membrane. This approach highlights the value of testing for related diseases using primer libraries and may be applied for other genetically heterogeneous orphan diseases. FUNDING: The Wellcome Trust, Muscular Dystrophy UK, Medical Research Council, European Community's Seventh Framework Programme "Integrated European -omics research project for diagnosis and therapy in rare neuromuscular and neurodegenerative diseases (NEUROMICS)"
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