3,188 research outputs found
Transition from rotating waves to modulated rotating waves on the sphere
We study non-resonant and resonant Hopf bifurcation of a rotating wave in
SO(3)-equivariant reaction-diffusion systems on a sphere. We obtained reduced
differential equations on so(3), the characterization of modulated rotating
waves obtained by Hopf bifurcation of a rotating wave, as well as results
regarding the resonant case. Our main tools are the equivariant center manifold
reduction and the theory of Lie groups and Lie algebras, especially for the
group SO(3) of all rigid rotations on a sphere
Risk of miscarriage following amniocentesis or chorionic villus sampling: systematic review of literature and updated meta-analysis
Objectives: To estimate the procedure-related risks of miscarriage after amniocentesis and trans-abdominal chorionic villus sampling (CVS) based on a systematic review of the literature and an updated meta-analysis.
Methods: A search of MEDLINE, EMBASE, and The Cochrane Library was carried out to identify studies reporting complications following CVS or amniocentesis. The inclusion criteria for the systematic review were studies reporting results from large controlled studies and those reporting data for pregnancy loss prior to 24 weeks’ gestation. Study authors were contacted when required to identify additional necessary data. Data for cases that had invasive procedure and controls groups were inputted in contingency tables and risk of miscarriage was estimated for each study. Summary statistics based on a fixed and random effects model were calculated after taking into account the weighting for each study included in the systematic review. Procedure-related risk of miscarriage was estimated as a weighted risk difference from the summary statistics for cases and controls. A subgroup analyses according to the similarity risk levels in the invasive testing and control groups was performed. Heterogeneity was assessed using Cochrane’s Q and I2 statistic. Egger Bias was estimated to assess reporting bias in published studies. Summary statistics for procedure-related risk of miscarriage were graphically represented in Forest plots.
Results: The electronic search from the databases yielded 2,943 potential citations, from which, we selected 20 controlled studies for inclusion in the systematic review to estimate the procedure-related risk of miscarriage from invasive procedures. There were a total of 580 miscarriages from 63,273 amniocentesis procedures with a weighted risk of pregnancy loss of 0.91% (95%CI: 0.73 to 1.09). In the control group, there were 1,726 miscarriages in 330,469 pregnancies with a loss rate of 0.58% (95CI%: 0.47 to 0.70). The weighted procedure-related risk of miscarriage was 0.30% (95%CI: 0.11 to 0.49, I2=70.1%). There were a total of 163 miscarriages from 13,011 CVS procedures with a risk of pregnancy loss of 1.39% (95%CI: 0.76 to 2.02). In the control group, there were 1,946 miscarriages in 232,680 pregnancies with a loss rate of 1.23% (95CI%: 0.86 to 1.59). The weighted procedure-related risk of miscarriage following CVS was 0.20% (95%CI: -0.12 to 0.52, I2=51.9%). However, when only studies with similar risk profiles between the intervention and control groups were considered, the procedure related risk for amniocentesis became 0.03% (95%CI -0.08 to 0.14, I2=0%) and for CVS -0.38 (95% CI -1.12 to 0.36, I2=0%).
Conclusion: The procedure-related risks of miscarriage following amniocentesis and CVS are lower than currently quoted to women. The risk appears to be negligible when these interventions are compared to control groups of the same risk profile
Forced Symmetry Breaking from SO(3) to SO(2) for Rotating Waves on the Sphere
We consider a small SO(2)-equivariant perturbation of a reaction-diffusion
system on the sphere, which is equivariant with respect to the group SO(3) of
all rigid rotations. We consider a normally hyperbolic SO(3)-group orbit of a
rotating wave on the sphere that persists to a normally hyperbolic
SO(2)-invariant manifold . We investigate the effects of this
forced symmetry breaking by studying the perturbed dynamics induced on
by the above reaction-diffusion system. We prove that depending
on the frequency vectors of the rotating waves that form the relative
equilibrium SO(3)u_{0}, these rotating waves will give SO(2)-orbits of rotating
waves or SO(2)-orbits of modulated rotating waves (if some transversality
conditions hold). The orbital stability of these solutions is established as
well. Our main tools are the orbit space reduction, Poincare map and implicit
function theorem
Monte Carlo study of the evaporation/condensation transition on different Ising lattices
In 2002 Biskup et al. [Europhys. Lett. 60, 21 (2002)] sketched a rigorous
proof for the behavior of the 2D Ising lattice gas, at a finite volume and a
fixed excess \delta M of particles (spins) above the ambient gas density
(spontaneous magnetisation). By identifying a dimensionless parameter \Delta
(\delta M) and a universal constant \Delta_c, they showed in the limit of large
system sizes that for \Delta < \Delta_c the excess is absorbed in the
background (``evaporated'' system), while for \Delta > \Delta_c a droplet of
the dense phase occurs (``condensed'' system).
To check the applicability of the analytical results to much smaller,
practically accessible system sizes, we performed several Monte Carlo
simulations for the 2D Ising model with nearest-neighbour couplings on a square
lattice at fixed magnetisation M. Thereby, we measured the largest minority
droplet, corresponding to the condensed phase, at various system sizes (L=40,
>..., 640). With analytic values for for the spontaneous magnetisation m_0, the
susceptibility \chi and the Wulff interfacial free energy density \tau_W for
the infinite system, we were able to determine \lambda numerically in very good
agreement with the theoretical prediction.
Furthermore, we did simulations for the spin-1/2 Ising model on a triangular
lattice and with next-nearest-neighbour couplings on a square lattice. Again,
finding a very good agreement with the analytic formula, we demonstrate the
universal aspects of the theory with respect to the underlying lattice. For the
case of the next-nearest-neighbour model, where \tau_W is unknown analytically,
we present different methods to obtain it numerically by fitting to the
distribution of the magnetisation density P(m).Comment: 14 pages, 17 figures, 1 tabl
Research on a superconducting niobium-thorium eutectic alloy and superconducting composites
Superconducting niobium-thorium eutectic alloy and composite
Quantum-Assisted Solution Paths for the Capacitated Vehicle Routing Problem
Many relevant problems in industrial settings result in NP-hard optimization
problems, such as the Capacitated Vehicle Routing Problem (CVRP) or its reduced
variant, the Travelling Salesperson Problem (TSP). Even with today's most
powerful classical algorithms, the CVRP is challenging to solve classically.
Quantum computing may offer a way to improve the time to solution, although the
question remains open as to whether Noisy Intermediate-Scale Quantum (NISQ)
devices can achieve a practical advantage compared to classical heuristics. The
most prominent algorithms proposed to solve combinatorial optimization problems
in the NISQ era are the Quantum Approximate Optimization Algorithm (QAOA) and
the more general Variational Quantum Eigensolver (VQE). However, implementing
them in a way that reliably provides high-quality solutions is challenging,
even for toy examples. In this work, we discuss decomposition and formulation
aspects of the CVRP and propose an application-driven way to measure solution
quality. Considering current hardware constraints, we reduce the CVRP to a
clustering phase and a set of TSPs. For the TSP, we extensively test both QAOA
and VQE and investigate the influence of various hyperparameters, such as the
classical optimizer choice and strength of constraint penalization. Results of
QAOA are generally of limited quality because the algorithm does not reach the
energy threshold for feasible TSP solutions, even when considering various
extensions such as recursive, warm-start and constraint-preserving mixer QAOA.
On the other hand, the VQE reaches the energy threshold and shows a better
performance. Our work outlines the obstacles to quantum-assisted solutions for
real-world optimization problems and proposes perspectives on how to overcome
them.Comment: Submitted to the IEEE for possible publicatio
Spontaneous Breakdown of Superhydrophobicity
In some cases water droplets can completely wet micro-structured
superhydrophobic surfaces. The {\it dynamics} of this rapid process is analyzed
by ultra-high-speed imaging. Depending on the scales of the micro-structure,
the wetting fronts propagate smoothly and circularly or -- more interestingly
-- in a {\it stepwise} manner, leading to a growing {\it square-shaped} wetted
area: entering a new row perpendicular to the direction of front propagation
takes milliseconds, whereas once this has happened, the row itself fills in
microseconds ({\it ``zipping''})Comment: Accepted for publication in Physical Review Letter
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