A prospective comparative study to evaluate the efficacy and safety of mifepristone with misoprostol over misoprostol alone in induction of labour

Background: The clinical requirement for induction of labour arises from circumstances in which it is predicted that the outcome of the pregnancy will be better if it is artificially interrupted rather than being left to follow its natural course. The combination of Mifepristone and Misoprostol is now an established and highly effective and safe method for second and third trimester termination of pregnancy and also significantly reduces the induction delivery interval, has fewer side effects and complications and also reduces the dose of Misoprostol. Hence, an attempt is made in the present study to assess the efficacy of combination of Mifepristone and Misoprostol versus single drug Misoprostol alone for induction of labor.Methods: A prospective comparative study of 50 cases in each study group, one under Misoprostol induction (group 1) and one under Mifepristone plus Misoprostol induction (group 2) were done and observations made in terms of improvement in Bishop’s score, induction-delivery interval and requirement of subsequent doses of Misoprostol.Results: 64% of the patients were observed with improved Bishop’s score. Induction delivery interval was shorter in the group 2 and noteworthy feature is 46% patients did not require even a single dose of Misoprostol after cervical ripening with Mifepristone suggesting that only Mifepristone may be only drug required in future for induction.Conclusions: Mifepristone with Misoprostol is efficient combination for induction of labour as compared to Misoprostol alone

A study of tropical tropopause using MST radar

International audienceUsing the MST radar data of vertical wind, the characteristics of the tropical tropopause, following four different definitions, depending on 1) temperature lapse rate, 2) cold point, 3) convective outflow and 4) potential temperature lapse rate minimum, are studied. From the vertical wind data of the radar, the altitude profiles of temperature and horizontal divergence are derived, from which the tropopause levels corresponding to i) the lapse rate ii) cold point iii) convective outflow level and iv) potential temperature lapse rate minimum are determined. The convective outflow level and hence the convective tropopause altitude is determined, for the first time using the MST radar data. The tropopause altitudes and temperatures obtained following the four definitions are compared on a day-to-day basis for the summer and winter seasons. Winter and summer differences in the tropopause altitude and temperature are also studied. Keywords. Meteorology and atmospheric dynamics (convective process; middle atmosphere dynamics; tropical meteorology

Research Issues in Cloud Computing

Cloud computing moved away from personal computers and the individual enterprise application server to services provided by the cloud of computers The emergence of cloud computing has made a tremendous impact on the Information Technology IT industry over the past few years Currently IT industry needs Cloud computing services to provide best opportunities to real world Cloud computing is in initial stages with many issues still to be addressed The objective of this paper is to explore the different issues of cloud computing and identify important research opportunities in this increasingly important area We present different design challenges categorized under security challenges Data Challenges Performance challenges and other Design Challenge

Observational constrained F(R,G)F(R, \mathcal{G}) gravity cosmological model and the dynamical system analysis

In this paper, we have analyzed the geometrical and dynamical parameters of $\mathcal{F}(R, \mathcal{G})=\alpha R^2 \mathcal{G}^\beta$ cosmological model, ($R$, $\mathcal{G}$ being the Ricci scalar and Gauss-Bonnet invariant respectively), constraining the parameters through the cosmological data sets. It is exhibited that the model admits a viable radiation era, and early deceleration followed by late-time acceleration in the matter-dominated era. From the phase-space, portrait stability criterion has been analysed, restricting the parameter $\beta$, different from $\beta=-1$. Additionally, we have explored the stability of the model from the behavior of critical points and obtained the present value of the density parameter for matter-dominated and dark energy components, which are identical to those obtained through cosmological data sets.Comment: 22 pages, 6 figure

Effect of tool pin diameters on friction stir welding of Aluminium alloy 5083

Friction stir welding is a solid-state welding process invented by the welding institute (TWI) of UK in 1991. The main objective is to study the effect of rotational speed and tool pin diameters of straight cylindrical tool on mechanical properties of Aluminium Alloy5083. Three different tool pin diameters (2.5mm,4mm,6mm) have been used to fabricate the joints at three different tool rotational speeds (710,1120 and 1400rpm) by keeping the constant welding speed and axial force. Tensile properties and micro hardness of the joints have been evaluated

The Origin of X-shaped Radio Galaxies: Clues from the Z-symmetric Secondary Lobes

Existing radio images of a few X-shaped radio galaxies reveal Z-symmetric morphologies in their weaker secondary lobes which cannot be naturally explained by either the galactic merger or radio-lobe backflow scenarios, the two dominant models for these X-shaped radio sources. We show that the merger picture can explain these morphologies provided one takes into account that, prior to the coalescence of their supermassive black holes, the smaller galaxy releases significant amounts of gas into the ISM of the dominant active galaxy. This rotating gas, whose angular momentum axis will typically not be aligned with the original jets, is likely to provide sufficient ram pressure at a distance ~10 kpc from the nucleus to bend the extant jets emerging from the central engine, thus producing a Z-symmetry in the pair of radio lobes. Once the two black holes have coalesced some 10^7 yr later, a rapid reorientation of the jets along a direction close to that of the orbital angular momentum of the swallowed galaxy relative to the primary galaxy would create the younger primary lobes of the X-shaped radio galaxy. This picture naturally explains why such sources typically have powers close to the FR I/II break. We suggest that purely Z-symmetric radio sources are often en route to coalescence and the concomitant emission of substantial gravitational radiation, while X-shaped ones have already merged and radiated.Comment: 12 pages, 1 compressed figure; accepted for publication in ApJ Letter

Classification of Acute Leukemia using Fuzzy Neural Networks

Accurate classification of cancers based on microarray gene expressions is very important for doctors to choose a proper treatment. In this paper, we compared ten filter based gene selection methods in order to differentiate acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) in leukemia dataset. Dimensionality reduction methods, such as Spearman Correlation Coefficient and Wilcoxon Rank Sum Statistics are used for gene selection. The experimental results showed that the proposed gene selection methods are efficient, effective, and robust in identifying differentially expressed genes. Adopting the existing SVM-based and KNN-based classifiers, the selected genes by filter based methods in general give more accurate classification results, typically when the sample class sizes in the training dataset are unbalanced