Dress and address in hospital psychiatry: an issue?

Background and aims: To assess the preferences of Dutch psychiatric patients in three general hospital psychiatric settings for the dress of psychiatrists and patients preference to be addressed by psychiatrists. To assess the associations concerning different clothing styles and the attributes of the patient-doctor relationship. Methods: One hundred and seventy-three adults, in and outpatients (aged 18-89 years) attending the psychiatry departments of three general hospitals, were included during the period June 2015 to May 2016. In these hospitals, the psychiatrist staff has different clothing policies. Data were analyzed with SPSS21. Results: Divided over the three hospitals, 173 patients were included, 96 inpatients and 77 outpatients. The patients' opinions on the psychiatrists' dress differed significantly between the hospitals in line with the local hospital clothing policy (p = 0.002 for the male psychiatrists, p = 0.000 for the female psychiatrists). The patients' ethnicity significantly influenced their preferences for dress and address, as a majority of the patients with a non-Dutch ethnic background expressed a preference for white coats, and address by surname (RR = 2.0, p = 0.003 for male and RR = 2.1 p = 0.002 for female psychiatrists). A significant difference in preference for being addressed by their first names by the psychiatrist was found between Dutch and non-native Dutch patients (RR = 2.6, p = 0.005). According to patients, the male psychiatrist in trousers and a long sleeve shirt and female psychiatrist in casual clothing were most often associated as being the friendliest, a white coat as being the most competent, and wearing smart attire as being the most accessible. Conclusion: Patients' preferences are in line with current local clothing habits. Ethnicity, setting and country influence a patient's preferences. Casual clothing for psychiatrists is assessed as being the friendliest but as the least competent, and white coats are assessed as being the most competent but as being less friendly and less accessible

Sport en criminaliteit

ARTIKELEN: R. Stokvis - Sport en corruptie B. Heere - Malversaties in de voetbalwereld; amateurisme, verdeeldheid en de schimmige transfermarkt J. de Boer - Scoren met kinderen; handel in jeugdige voetballers H.T. van Staveren - De juridische basis van het 'dopingverbod' in de sport W. Bos, H. de Doelder - Berechting van 'sportief' wangedrag; aspecten van straf- en tuchtrecht in de sport M. Theeboom - Vechtsporten; leren vechten of ... leren niet te vechten? SAMENVATTING: Met de toenemende verzakelijking van de sport komen steeds meer zaken aan het licht die moeilijk anders dan crimineel genoemd kunnen worden. Dit themanummer van Justitiële verkenningen werpt vanuit verschillende invalshoeken nader licht op de combinatie sport en criminaliteit

Crise hystéro-confusionnelle, comme réaction névrotique de fuite ou de défense: contribution à la psychodynamique des états de panique

Relation détaillée clinico-psychologique d'une crise hystéro-confusionnelle survenue brusquément à la suite d'un choc émotif chez une célibataire de 30 ans. L'étude des antécédentes, très riches en traumatismes psychiques, a permis de jeter une lumière sur les mécanismes intimes de la réaction névrotique de fuite ou de défense (Sturmbewegung, de Kretschmer) devant une situation considérée comme insuportable. Ainsi est apporté une contribution à la psychologie dynamique des états de panique. Leur thérapeutique psychologique est d'autant plus aisée que l'on a affaire à des personnalités différenciées. D'ici le succès obtenu dans le cas présent

Stable isotope dilution assay for the accurate determination of mycotoxins in maize by UHPLC-MS/MS

A fast, easy-to-handle and cost-effective analytical method for 11 mycotoxins currently regulated in maize and other cereal-based food products in Europe was developed and validated for maize. The method is based on two extraction steps using different acidified acetonitrile–water mixtures. Separation is achieved using ultrahigh-performance liquid chromatography (UHPLC) by a linear water–methanol gradient. After electrospray ionisation, tandem mass spectrometric detection is performed in dynamic multiple reaction monitoring mode. Since accurate mass spectrometric quantification is hampered by matrix effects, uniformly [13C]-labelled mycotoxins for each of the 11 compounds were added to the sample extracts prior to UHPLC-MS/MS analysis. Method performance parameters were obtained by spiking blank maize samples with mycotoxins before as well as after extraction on six levels in triplicates. The twofold extraction led to total recoveries of the extraction steps between 97% and 111% for all target analytes, including fumonisins. The [13C]-labelled internal standards efficiently compensated all matrix effects in electrospray ionisation, leading to apparent recoveries between 88% and 105% with reasonable additional costs. The relative standard deviations of the whole method were between 4% and 11% for all analytes. The trueness of the method was verified by the measurement of several maize test materials with well-characterized concentrations. In conclusion, the developed method is capable of determining all regulated mycotoxins in maize and presuming similar matrix effects and extraction recovery also in other cereal-based foods

Spisulosine (ES-285) given as a weekly three-hour intravenous infusion: results of a phase I dose-escalating study in patients with advanced solid malignancies

Spisulosine is a marine compound that showed antitumor activity in preclinical studies. We report results of a phase I trial performed in patients with advanced solid tumors with the marine compound, with the aim to determine the maximum tolerated dose (MTD) of a weekly 3-h intravenous (iv.) infusion, and to evaluate the safety, efficacy, and pharmacokinetics (PK) of the compound. Two centers contributed 25 patients to the trial, and 7 dose levels were explored. In dose levels ranging from 4 to 128 mg/mA(2)/day, no dose-limiting toxicities (DLT) were observed. One patient had DLT at 200 mg/mA(2), a reversible grade 3 ALT increase. The MTD was not reached due to early termination of the Spisulosine trial program but is considered to be likely in the range of 200 mg/mA(2) for this schedule. Drug-related adverse reactions included mild to moderate nausea, pyrexia, injection site reactions, and vomiting. One case of grade 4 peripheral motor and sensory neuropathy associated with general weakness and pain was observed during treatment cycle 4 and possibly contributed to the death of the patient. Grade 3 laboratory abnormalities included anemia and lymphopenia and increases in liver enzymes (alkaline phosphatase, transaminases, and bilirubin). Objective responses were not observed, and only four patients had short-lasting stable disease (< 3 months). The PK data indicated a wide distribution, a long residence time, and dose proportionality of the agent. Hepato- and neuro-toxicity are schedule independent dose-limiting adverse events for this marine compound, as illustrated by this and other early clinical trials

How to Influence National Pride? The Olympic Medal Index as a Unifying Narrative

Elite sport is often regarded as one of the main vehicles for articulating national pride and stimulating national cohesion. In this article, we explore a variety of different notions of pride and nationality as related to success in elite sport. We present the results of a public survey, which measured some of the effects on national pride in the Netherlands, related to the men's European Football Championships, the Tour de France, Wimbledon and the Olympic Games in Beijing (all in the summer of 2008). The results suggest that a sense of belonging is a necessary condition that precedes rather than results from sport-related pride. This supports the notion of national pride being a rather stable characteristic of countries, notwithstanding specific situations (such as sport success) that may lead to minor and temporary fluctuations. There seems to be no empirical evidence for the - primarily quantitatively understood - concept of pride (as a 'bucket-notion'), which is often implicit to the political rhetoric used to increase sport funding with the aim of winning more medals to generate an increase in national pride. © The Author(s) 2010

Measuring the restoration trajectory of invertebrates in the Winstone Aggregates Hunua quarry site

In this study we surveyed Winstone Aggregates Hunua Quarry restoration plantings for invertebrates. We wanted to measure the restoration success and used an unplanted control site and a mature forest site in the same area as a comparison. Using different entomological surveying techniques we found that ground beetle and centipede numbers increased from the control site through to the mature forest. Tree weta was well represented in the restored area, while ants, earthworms and rove beetles resulted in a downwards trend from the mature area to the control site. Five native species of snail were found only in the mature forest. Previous studies such as Bowie et al. (2012) Punakaiki restoration project, found similar trends. Both this study and the Punakaiki project are baseline studies. Further research is proposed for the future