Optical Properties of Zirconium Doped Sodium-Boro-Zinc Fluoride Glasses

Effect of Zirconium doped sodium borate glasses with zinc fluoride and without zinc fluoride glasses were prepared individually by conventional melt quench method. All the Samples were analyzed using certain measurements like UV-Visible and Photoluminescence. UV-Visible spectra evidences that after 1mol% incorporation to glass matrix there exist 3F2-3P1 transition due to Zr2+ ions in both Zr:Zf glass series. Further; using Tauc's equation direct and indirect band gaps were estimated for all samples. Upon the excitation 365nm and 383nm the PL studies were carried out to know the possible transitions and the role of Zirconium in both glass series for the same CIE diagram was done

Automated ECG Analysis for Localizing Thrombus in Culprit Artery Using Rule Based Information Fuzzy Network

Cardio-vascular diseases are one of the foremost causes of mortality in today’s world. The prognosis for cardiovascular diseases is usually done by ECG signal, which is a simple 12-lead Electrocardiogram (ECG) that gives complete information about the function of the heart including the amplitude and time interval of P-QRST-U segment. This article recommends a novel approach to identify the location of thrombus in culprit artery using the Information Fuzzy Network (IFN). Information Fuzzy Network, being a supervised machine learning technique, takes known evidences based on rules to create a predicted classification model with thrombus location obtained from the vast input ECG data. These rules are well-defined procedures for selecting hypothesis that best fits a set of observations. Results illustrate that the recommended approach yields an accurateness of 92.30%. This novel approach is shown to be a viable ECG analysis approach for identifying the culprit artery and thus localizing the thrombus

Effect of calcium channel blocker as anticonvulsant and its potentiating effect when used along with sodium valproate in pentylenetetrazole induced seizures in Albino rats

Background: Many antiepileptic drugs were introduced for the treatment of epilepsy. Ideal antiepileptic drug should not only prevent but also correct the underlying pathophysiology without altering the normal neurotransmission. Calcium channel blockers may form such group because initiation of seizure is associated intrinsic burst firing which is triggered by large inward calcium current, so this study was done to evaluate the anticonvulsant effect of amlodipine in albino rats.Methods: A total of 42 adult albino rats were included in the study and divided into 7 groups, each containing 6 rats. Group 1 received distilled water, group 2,3 received sodium valproate 50mg/kg and 100mg/kg, group 4-6 received amlodipine 1, 2, 4mg/kg and group 7 received combination of Amlodipine 1 mg/kg and sodium valproate 50mg/kg. Pentylenetetrazole induced seizures model was done and onset of myoclonic jerks, onset of clonic convulsions and duration of clonic convulsions was studied.Results: There was a significant anticonvulsant effect in Amlodipine doses 2, 4mg/kg (p <0.001). The combination of Amlodipine (1mg/kg) and Sodium valproate (50mg/kg) also had significant anticonvulsant effect.Conclusions: Amlodipine, a calcium channel blocker has anticonvulsant effect and also potentiated the anticonvulsant effect of low dose sodium valproate

Bruxism: Prevalence among Software Professionals

Background: Software professionals perform boundary-spanning activities and are always at the fear of job security and cost cut-offs. These characteristics of the software professionals are bound to have massive impact on their healthy living. Many studies have related bruxism with stress. Thus, this study is conducted to know the prevalence of bruxism among software professionals. Aims: To know the prevalence of bruxism among software professionals. Methods: A total of 232 randomly selected software professionals working for NASSCOM registered Bangalore based software companies were considered for the study. A questionnaire was specially developed to know the study subject&rsquo;s demographic data, self reported bruxism data, details on personal habits and other details. The bruxism was recorded as per the ASDA clinical research diagnostic criteria for bruxism. The data was subjected to statistical analysis. &nbsp;Results: In the study sample, prevalence of bruxism was 35.5% with no difference between genders. Bruxism rarely occurs alone. Conclusion: The prevalence of bruxism in the study population is 35.5%.The results of this study raise an important concern about the prevalence of bruxism among software professionals

Evaluation of anticonvulsant activity of amlodipine in albino rats

Background: The objective of the study was to evaluate the anticonvulsant activity of amlodipine in albino rats.Methods: Anticonvulsant activity of amlodipine was done in three graded doses (1 mg/kg, 2 mg/kg, 4 mg/kg), and combination group with low dose of amlodipine (1 mg/kg) and standard drug (phenytoin) in maximal electroshock seizures (MES) experimental animal model.Results: Amlodipine in dose of 2, 4 mg/kg showed dose dependent significant anticonvulsant effect and combination of low dose amlodipine and low dose of standard drug also showed significant anticonvulsant effect in MES model.Conclusions: Amlodipine is having anticonvulsant activity and also potentiated the anticonvulsant effect of phenytoin in MES model.

Efficacy of 5HT3 receptor antagonist ondansetron antidepressant activity in physical induced albino mice

Background: The objective of this study was to evaluate efficacy of 5HT3 receptor antagonist ondansetron antidepressant activity in physical induced swiss albino mice.Methods: Study was placebo controlled, randomized laboratory based comparative study with prior permission of Institutional animal ethical committee. Experimental animals were divided in to seven groups as control (distilled water 10ml/kg), standard Fluoxetine two doses (10mg/kg and 20mg/kg) , test drug ondansetron three doses (0.5mg/kg, 1mg/kg and 2mg/kg) and combinations of test and standard (0.5mg/kg + 10mg/kg).The drugs were administered intraperitonium and antidepressant activity was recorded using physically induced depression models tail suspension test and despair swim test.Results: Ondansetron treated albino mice groups with dose dependent increase of 0.5mg/kg, 1.0mg/kg and 2.0mg/kg showed significant decrease in antidepressant activity and increase in catalepsy score when compared with fluoxetine 10mg/kg and 20mg/kg. Combination doses showed stastically significant antidepressant activity.Conclusions: The present study indicates ondansetron showed promising antidepressant activity due to its ability to modulate serotonergic system and has proved to be safe in the dose range of 0.5mg/kg, 1mg/kg and 2mg/kg in mice

Addressing the challenges of Visually Impaired using IoT

Internet of Things is a new revolution of the Internet. IoT allows networked objects to be sensed and controlled remotely, creating opportunities for more direct integration of the physical world into computer-based systems, resulting in reduced human intervention. People with complete blindness or low vision often have a difficult time self-navigating in unusual environments. In fact, mobility is one of the biggest challenges for visually Impaired. IoT offers the assistance and support to the visually impaired people to achieve a quality life allowing them to involve in social activities. Assistive IoT technologies are powerful tools to increase independence and improve participation. Therefore, the purpose of this paper is to analyze how people with visual impairment can interact with and benefit from the IoT

CBDC: EMPIRICAL STUDY ON DETERMINANTS OF CBDC USAGE PURPOSE AMONG CONSUMERS

Abstract The initiative from the government of India in making India into a digitally vibrant nation is highly admirable. India economic growth over the decade is raising at higher rate, it due to adoption of digitalization in every part of economy from banking, business, and international payment. Banks are updating according to needs and demands of the consumers providing amenable services at finger tips of the consumers. From small vendor to high business transitions are carry forward with the help of digital transition or digital currency. The primary objective of the study is determining CBDC usage purpose among consumers. The study used convenient sampling method and covered 160 banking consumers using digital banking. The findings of the study show Determinants of CBDC Usage Purpose among Consumers have been segregated into two dominant dimensions namely Payment Terminal and Financial Statibility Factor which dealing with cost of using online banking, usage of the same at all branches both nationally and internationally and security of the banking. The second factor is Usage and Payment Efficiency Factor which deals with usage of the digital banking, efficiency of the payment over the geographical location and ability of use the same without internet connections. Consumer Perception on CBDC have been segregated into two dominant dimensions namely Expectancy and Performance Factor which deals with expectancy of the consumers over usage of CBDC, knowledge on using digital currency and trust over the banking while using digital currency. A positive and significant impact of Consumer Perception on CBDC on Determinants of CBDC Usage Purpose among Consumers has been identified

Solitary Mandibular Lesion as the Presenting Sign of Multiple Myeloma: A Rare Case Report

Multiple myeloma (MM) is a rare hematological malignancy caused by monoclonal proliferation of plasma cells in the marrow of various bones. It is more common in men in the sixth and seventh decade of life. Patients usually present with bone pain, fatigue, recurrent infections, renal failure and nervous system dysfunction. Rarely, oral lesions may be the initial sign of multiple myeloma presenting with pain, jaw swelling, tooth mobility, multiple punched out radiolucencies and parasthesia. A case of multiple myeloma occurring in a 71 year old male patient who presented with a solitary lesion in the mandible is presented here. This paper highlights the importance of knowing oral manifestations of multiple myeloma and interdisciplinary approach required for early diagnosis

CIRCULARLY POLARIZED U SLOT MICROSTRIP PATCH ANTENNA

A novel miniaturized circularly polarized microstrip patch antenna with improved characteristics operating at 2.3 GHz using IE3D software is proposed. An asymmetrical U-slot is discussed to generate the two orthogonal modes for circular polarization without cutting a sloping edge to any corner of the probe fed square patch antenna. Circular polarization reduces the loss caused by the misalignment between the signal and the receiving antenna. The center frequency of the designed antenna is widely applied to applications such as satellite communication systems like MSAT and GPS. A parametric study has been carried out to investigate the effects caused by different arm lengths of U-slot, width of slot, height of slot and gap between the arms of U-slot