A CASE REPORT ON BENIGN PROSTATIC HYPERPLASIA WITH HOMEOPATHIC REMEDIES

Benign prostatic hyperplasia (BPH) is characterized by proliferation of the cellular elements of the prostate. The complications faced by elderly people need to be minimized and most of elderly don not prefer a surgical approach. Therefore, treatment of BPH with medicines is prioritized by elderly people. The present case report adds a little to the field that how to treat BPH cases in elderly without surgical approach but with homeopathic formulations. Case report presented here is diagnosed case of BPH having grade III prostatomegaly on USG. Patient presented with increased frequency of urination in feeble stream and sudden urging occasionally. Patient was treated with homoeopathic medication and assessed using Ultrasonography, International Prostate Symptom Score, and Uroflowmetry with significant improvement. Hence, it is suggestive that homoeopathic treatment could be effective in the management of cases of BPH in elderly people. Keywords: Homoeopathy, BPH, Uroflowmetry, International Prostate Symptom Score (IPSS), Constitutional medicine, Organopathic medicine, Sabal serrulat

Properties and physiological effects of dietary fiber-enriched meat products: a review

Meat is a rich source of high biological proteins, vitamins, and minerals, but it is devoid of dietary fiber, an essential non-digestible carbohydrate component such as cellulose, hemicellulose, pectin, lignin, polysaccharides, and oligosaccharides. Dietary fibers are basically obtained from various cereals, legumes, fruits, vegetables, and their by-products and have numerous nutritional, functional, and health-benefiting properties. So, these fibers can be added to meat products to enhance their physicochemical properties, chemical composition, textural properties, and organoleptic qualities, as well as biological activities in controlling various lifestyle ailments such as obesity, certain cancers, type-II diabetes, cardiovascular diseases, and bowel disorders. These dietary fibers can also be used in meat products as an efficient extender/binder/filler to reduce the cost of production by increasing the cooking yield as well as by reducing the lean meat content and also as a fat replacer to minimize unhealthy fat content in the developed meat products. So, growing interest has been observed among meat processors, researchers, and scientists in exploring various new sources of dietary fibers for developing dietary fiber-enriched meat products in recent years. In the present review, various novel sources of dietary fibers, their physiological effects, their use in meat products, and their impact on various physicochemical, functional, and sensory attributes have been focused

A comparative study of hepatic mitochondrial oxygen consumption in four vertebrates by using Clark-type electrode

The present study was undertaken to establish a comparative account on hepatic mitochondrial oxygen consumption of Clarias gariepinus (fish), Bufo melanostictus (amphibian), Gallus gallus (bird) and Rattus norvegicus (mammal) and to correlate it with their specific metabolic rate (SMR). Mitochondrial oxygen consumption was measured with a Clarke-type electrode with succinate and pyruvate/malate as substrates. ADP was used to start state-III respiration. The results show that rats and chickens have higher oxygen consumption rate than that of fish and toads. Similarly, a species and substrate specific difference was also noticed in P/O (phosphate utilized per oxygen atom) ratio and respiratory control index. In case of rat, a significant negative correlation was noticed between P/O ratio and SMR with succinate as substrate. It is surmised that the observed difference in the mitochondrial respiration and P/O ratio in the above vertebrates is due to the difference in their metabolic activities

BENIGN PROSTATIC HYPERPLASIA AND HOMOEOPATHIC TREATMENT: CASE STUDY WITH OF A 64 YEARS OLD PATIENT

Benign Prostatic hyperplasia (BPH) is a nodular hyperplasia, in which there is enlargement of the gland due to the formation of one or more nodules. Case report presented here is a diagnosed case of BPH having grade IV prostatomegaly on USG. Patient presented with the complaint of thin and feeble stream of urine along with frequent urination and sudden urging for urination Patient was treated with homoeopathic medication (constitutional medicine followed by organ remedy) and assessed with the help of ultrasonography, International Prostate Symptom Score (IPSS)& Uroflowmetry which showed significant improvement. Thus, homeopathic treatment can reduce urinary frequency, improve urine flow and reduce the size of enlarged prostate. Keywords: Homoeopathy, BPH, uroflowmetry, USG, IPSS questionnaire, constitutional medicine, Hydrangea arborescen

Investigating the Conformational Structure and Potential Site Interactions of SOD Inhibitors on Ec-SOD in Marine Mud Crab Scylla serrata: A Molecular Modeling Approach

© 2015, International Association of Scientists in the Interdisciplinary Areas and Springer-Verlag Berlin Heidelberg. Superoxide dismutases (SODs) act as a first line of the enzymatic antioxidant defense system to control cellular superoxide anion toxicity. Previously, several inhibitors have been widely identified and catalogued for inhibition of SOD activity; however, still the information about the mechanism of interaction and points toward the inhibitor interactions in structures of SODs in general and in extracellular (Ec)-SOD in particular is still in naive. In the present research, we present an insight to elucidate the molecular basis of interactions of SOD inhibitors with Ec-SOD in mud crab Scylla serrata using molecular modeling and docking approaches. Different inhibitors of SOD such as hydrogen peroxide ( H 2O2) , potassium cyanide, sodium dodecyl sulfate (SDS), β-mercaptoethanol and dithiocarbamate were screened to understand the potential sites that may act as sites for cleavage or blocking in the protein. SOD–SDS and SOD - H 2O2 complex interactions indicate residues Pro72 and Asp102 of the predicted crab Ec-SOD as common targets. The GOLD result indicates that Pro72, Asp102 and Thr103 are commonly acting as the site of interaction in Ec-SOD of S. serrata with SOD inhibitors. For the first time, the results of this study provide an insight into the structural properties of Ec-SOD of S. serrata and define the possible involvements between the amino acids present in its active sites, i.e., in the regions from 70 to 84 and from 101 to 103 and different inhibitors

Pulsed laser surface treatment of magnesium alloy: Correlation between thermal model and experimental observations

The effect of deposition of Al +Al2O3 on MRI 153 M Mg alloy processed using a pulsed Nd:YAG laser is presented in this study. A composite coating with metallurgical joint to the substrate was formed. The microstructure and phase constituents were characterized and correlated with the thermal predictions. The laser scan speed had an effect on the average melt depth and the amount of retained and/or reconstituted alumina in the final coating. The coating consisted of alumina particles and highly refined dendrites formed due to the extremely high cooling rates (of the order of 10(8) K/s). The microhardness of the coating was higher and several fold improvement of wear resistance compared to the substrate was observed for the coatings. These microstructural features and physical properties were correlated with the effects predicted by a thermal model